DOI QR코드

DOI QR Code

Usefulness of Color-overlay Pattern of Breast Elastic Ultrasonography

유방 탄성초음파의 Color overlay pattern에 대한 유용성

  • An, Hyun (Department of Radiology, Inje University Busan Paik Hospital) ;
  • Im, In-Chul (Department of Radiological Science, Dongeui University)
  • 안현 (인제대학교 부산백병원 영상의학과) ;
  • 임인철 (동의대학교 방사선학과)
  • Received : 2017.09.25
  • Accepted : 2017.10.31
  • Published : 2017.10.31

Abstract

Breast cancer rates are increasing every year, biopsy for diagnosing breast cancer is increasing as well. Biopsy also invasive test, have bad side effects from patients anxiety, infection, bleeding. In this study, Conduct a survey of 69 patients who brest lesion patient, both B-mode ultrasound and elastography exam and B-mode ultrasound was classified according to the BI-RADS category, and the elastography exam was classified according to the Color overlay pattern that the value of the kPa expressed in relation to the propagation velocity of Transverse waves. The optimal cut off value of the highest sensitivity and specificity was 54.70 kPa. In the color overlay pattern, Dark Blue 42 people, Light blue ~ Red 27 people classified results and BI-RADS classification results, benign 40 people and malignant 29 people classified results showed similar results. Therefore, It is judged that the color overlay pattern is positive when classified into Dark Blue, and malignant when classified into Light blue ~ Red. In conclusion, breast elastography is expected to play a innovative role in reducing the number of breast cancer examinations and classify between benign and malignant tumor.

유방암 발생률이 해마다 증가하여 그에 따라 유방 종양을 진단하는 검사인 조직검사의 횟수도 같이 증가하고 있다. 조직검사는 침습적 검사로써 환자들의 불안감과 감염, 출혈 등의 부작용이 발생하고 있다. 본 연구에서는 유방 병변 환자를 대상으로 회색조 초음파와 탄성초음파검사 모두 실시한 69명을 대상으로 회색조 초음파는 BI-RADS Category에 따라 분류하고, 탄성초음파검사는 횡파의 전파 속도를 환산하여 나타낸 kPa값을 Color overlay pattern으로 분류하였다. 민감도와 특이도의 합이 가장 높은 최적의 Cut-off value는 54.70 kPa로 나타났다. Color overlay pattern에서 Dark Blue 42명, Light blue ~ Red 27명으로 분류된 결과와 BI-RADS Category 분류 결과인 양성 40명, 악성 29명으로 분류된 결과가 유사하다. 따라서 Color overlay pattern에서 Dark Blue에 분류될 경우에는 양성, Light blue ~ Red에 분류될 경우에는 악성으로 의심할 수 있을 것으로 판단된다. 결론적으로 유방 탄성초음파는 무분별한 유방 조직검사의 횟수를 줄이고 양성종양과 악성종양을 구분하는데 획기적인 역할을 할 것으로 사료된다.

Keywords

References

  1. H. G. Kim, "FEM Breast Modeling for X-ray Elasto-Mammography", Department of Biomedical Engineering, Kyung Hee University, 2011.
  2. E. H. Yang, "Conventional Sonography and Sonoelastographic diagnostic performances in the patients of breast biopsy", Graduate School of Public Health Ajou University, 2017.
  3. J. H. Lee, S. H. Kim, B. J. Kang, et al. "Role and clinical usefulness of elastography in small breast masses" Academic Radiology, Vol. 18, No. 1, pp. 74-80, 2011. https://doi.org/10.1016/j.acra.2010.07.014
  4. T. Hall, W. Svensson, P, Von Behren, et al. "Lesion size ratio for differentiating breast masses". IEEE Ultrasonics Symposium, Vol. 2, pp. 1247-50, 2003.
  5. N. Cho, C. Y. Lyou, J. S. Park, et al. "Distinguishing benign from malignant masses at breast US: combined US elastography and color Doppler US-influence on radiologist accuracy". Radiology, Vol. 262, No. 1, pp. 80-90, 2012. https://doi.org/10.1148/radiol.11110886
  6. F. K. Schaefer, I. Heer, P. J. Schaefer, et al. "Breast ultrasound elastography-Results of 193 breast lesionsin a prospective study with histopathologic correlation", European Journal Radiology, Vol. 77, No. 3, pp. 450-456, 2011. https://doi.org/10.1016/j.ejrad.2009.08.026
  7. I. S. Woo, "Feasibility study for the breast ultrasound elastography in the diagnosis of breast cancer and assessment of the influence of the image acquisition direction, Department of Medical Imaging Engineering", The Graduate school of Bio-Medical sciences, Korea university, 2012.
  8. Y. S. Jung, H. Shim, M. G. Lee, Y. H. Kim, Y. S. Park, "Breast Cancer Diagnosis Using the Ultrasound Elastography", The Transactions of the Korean Institute of Electrical Engineers, Vol. 2014, No. 10, pp. 364-366. 2014.
  9. H. J. Shin, E. S. Ko, "Breast Cancer Screening in Korean Woman with Dense Breast Tissue", Journal of the Korean Radiological Society, Vol. 73, No. 5, pp. 279-286, 2015. https://doi.org/10.3348/jksr.2015.73.5.279
  10. J. Y. Park, "Analysis of diagnostic value and overlay color pattern of shear wave elastography in palpable breast mass", Korea University Graduate School Department of Medicine Department of Radiology, 2015.
  11. S. H. Lee, H. R. Koo, W. K. Moon etc. "Guideline for the Combined Elastography and Color Doppler Ultrasonography Examinations: KSBI/KSFBS 2013-02 Multicenter Study", Korean Journal of Breast Screening, Vol, 2, No. 10, pp. 136-144, 2013.
  12. J. Y. Park, W. O Hee, S. H Seon etc, "Diagnostic Performance and Color Overlay Pattern in Shear Wave Elastography for Palpable Breast mass", European Journal Radiology, Vol. 84, No. 10, pp. 1943-1948, 2015. https://doi.org/10.1016/j.ejrad.2015.06.020
  13. Y. J. Cha, J. H. Youk, B. G. Kim. "Lymphangiogenesis in Breast Cancer Correlates with Matrix Stiffness on Shear-Wave Elastography", Yonsei Medical university, Journal Vol. 57, No. 3, pp. 4-7, 2016.