Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Inherited Macrothrombocytopenia in a Cavalier King Charles Spaniel

  • Kim, Hyo-jin (Department of Veterinary Internal Medicine, College of Veterinary Medicine Konkuk University) ;
  • Choi, Seok-jin (Department of Veterinary Internal Medicine, College of Veterinary Medicine Konkuk University) ;
  • Kim, Seung-Gon (Department of Veterinary Internal Medicine, College of Veterinary Medicine Konkuk University) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine Konkuk University)
  • Received : 2017.01.31
  • Accepted : 2017.07.18
  • Published : 2017.08.31
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Abstract

A 1-year-old intact male Cavalier King Charles Spaniel was presented with a ruptured anal sac. On routine preanesthetic screening tests for surgical resection, the thrombocytopenia was observed by an impedance-type autoanalyzer. A peripheral blood smear was used as a follow-up test and giant platelets were seen on the smear. DNA assay of this patient confirmed that the cause of the platelet abnormalities in this patient was genetic mutation. To our knowledge, this is the first case report of macrothrombocytopenia confirmed based on the DNA assay results, in a Cavalier King Charles Spaniel in Korea.

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References

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