Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Skin Hydration Effect of Brasenia schreberi Mucilage Polysaccharide Extract

순채 점액질 다당체 추출물의 피부 보습 효과 연구

  • Ahn, Seyeon (Research Park, LG Household & Health Care Ltd.) ;
  • Gil, Soyeon (Research Park, LG Household & Health Care Ltd.) ;
  • Kwon, Ohsun (Research Park, LG Household & Health Care Ltd.) ;
  • Chang, Yunhee (Research Park, LG Household & Health Care Ltd.) ;
  • Jin, Mu Hyun (Research Park, LG Household & Health Care Ltd.)
  • 안세연 ((주)LG생활건강 기술연구원) ;
  • 길소연 ((주)LG생활건강 기술연구원) ;
  • 권오선 ((주)LG생활건강 기술연구원) ;
  • 장윤희 ((주)LG생활건강 기술연구원) ;
  • 진무현 ((주)LG생활건강 기술연구원)
  • Received : 2017.07.28
  • Accepted : 2017.09.08
  • Published : 2017.09.30
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Abstract

In this study, we evaluated the skin moisturizing effect of Brasenia schreberi (B. schreberi) mucilage polysaccharide on human skin and in vitro and the potent cosmetic ingredient for skin. To protect skin from various environmental stresses and aging, we should increase moisture content of skin and prevent water loss. We have found that polysaccharides extracted from mucilage of B. schreberi improved the roughness of skin with its lubricating behavior. In vitro, the expression of transglutaminase 1 (TGM1) gene, which plays a role in cross-linking the skin barrier, was increased when the keratinocytes were treated with B. schreberi polysaccharides. In addition, the expression of hyaluronan synthase 3 (HAS3) gene, an enzyme that synthesizes water-binding matrix hyaluronic acid, aquaporin 3 (AQP3), which regulates the movement of water and glycerol were also increased. In addition, an experiment to evaluate its potential as a cosmetic ingredient has shown anti-inflammatory and collagen synthesis-promoting effects. As a result, the mucilaginous polysaccharide from natural products which has not existed before, showed moisturizing effect, anti-inflammation and collagen synthesis-promoting effects for skin protection and hydration.

본 연구는 순채 점액질 다당체의 인체 피부와 in vitro에서의 피부 보습효과를 확인하고 화장품 원료로서의 가능성을 평가하기 위한 것이다. 다양한 환경적 스트레스와 노화로부터 피부를 보호하기 위해서는 피부의 수분 보유량을 증가시키고 수분의 손실을 예방해야 한다. 본 연구진은 순채의 점액질로부터 추출한 다당체를 인체 피부에 도포했을 때, 특이적인 윤활성으로 피부에서의 거칠기(roughness)를 개선시켰다는 것을 확인했다. In vitro에서 각질형성세포에 순채 점액질 다당체를 처리했을 때, 피부장벽의 가교 역할을 하는 transglutaminase 1 (TGM1) 유전자의 발현이 증가하였다. 또한 물과 글리세롤의 이동을 조절하는 막관통 단백질 aquaporin 3 (AQP3)와 수분 보유 기질 히알루론산을 합성하는 효소인 hyaluronan synthase 3 (HAS3) 유전자의 발현 또한 증가함을 확인했다. 추가적으로 화장품 원료로서의 가능성을 평가하기 위한 실험에서, 항염증과 콜라겐 합성 촉진 효능을 보였다. 결과적으로 순채의 점액질 다당체는 기존에 없는 새로운 천연 원료로서, 피부에 보습 효과와 항염증, 콜라겐 합성 촉진 효능이 있음을 밝혔다.

Keywords

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