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Differentiation of Deep Subcortical Infarction Using High-Resolution Vessel Wall MR Imaging of Middle Cerebral Artery

  • Bae, Yun Jung (Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Choi, Byung Se (Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Jung, Cheolkyu (Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Yoon, Yeon Hong (Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Sunwoo, Leonard (Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Bae, Hee-Joon (Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Kim, Jae Hyoung (Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital)
  • 투고 : 2016.10.07
  • 심사 : 2017.04.16
  • 발행 : 2017.12.01

초록

Objective: To evaluate the utility of high-resolution vessel wall imaging (HR-VWI) of middle cerebral artery (MCA), and to compare HR-VWI findings between striatocapsular infarction (SC-I) and lenticulostriate infarction (LS-I). Materials and Methods: This retrospective study was approved by the Institutional Review Board, and informed consent was waived. From July 2009 to February 2012, 145 consecutive patients with deep subcortical infarctions (SC-I, n = 81; LS-I, n = 64) who underwent HR-VWI were included in this study. The degree of MCA stenosis and the characteristics of MCA plaque (presence, eccentricity, location, extent, T2-high signal intensity [T2-HSI], and plaque enhancement) were analyzed, and compared between SC-I and LS-I, using Fisher's exact test. Results: Stenosis was more severe in SC-I than in LS-I (p = 0.040). MCA plaque was more frequent in SC-I than in LS-I (p = 0.028), having larger plaque extent (p = 0.001), more T2-HSI (p = 0.001), and more plaque enhancement (p = 0.002). The eccentricity and location of the plaque showed no significant difference between the two groups. Conclusion: Both SC-I and LS-I have similar HR-VWI findings of the MCA plaque, but SC-I had more frequent, larger plaques with greater T2-HSI and enhancement. This suggests that HR-VWI may have a promising role in assisting the differentiation of underlying pathophysiological mechanism between SC-I and LS-I.

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참고문헌

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  3. MR Intracranial Vessel Wall Imaging: A Systematic Review vol.30, pp.4, 2017, https://doi.org/10.1111/jon.12719
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