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Comparative Study of Physical Properties of Functional Ophthalmic Hydrogel Lens Using Photo and Thermal Polymerization

  • Kim, Duck-Hyun (Optometry & Vision Science, Catholic University of Daegu) ;
  • Seok, Jae-Wuk (Optometry & Vision Science, Catholic University of Daegu) ;
  • Sung, A-Young (Optometry & Vision Science, Catholic University of Daegu)
  • Received : 2017.08.07
  • Accepted : 2017.09.25
  • Published : 2017.09.30

Abstract

In this study, HEMA, MMA, AA, and EGDMA were used as basic combinations for manufacturing hydrophilic lenses for ophthalmic applications. In addition, AIBN (thermal polymerization initiator), 2H2M (photo polymerization initiator), and 3-hydroxypyridine (additive) were used to manufacture hydrophilic ophthalmic lenses through thermal polymerization and photo polymerization before their physical properties were measured. The results showed that when ophthalmic lenses were prepared via thermal polymerization and photo polymerization using 3-hydroxypyridine as an additive, their optical and physical properties and surface structures were different in each case, but they all satisfied the physical properties required for ophthalmic lenses.

Keywords

References

  1. L. Lecamp, B. Youssef, C. Bunel, and P. Lebaudy, "Photoinitiated polymerization of a dimethacrylate oligomer: 1. Influence of photoinitiator concentration, temperature and light intensity", Polymer, Vol. 38, pp. 6089-6096, 1997. https://doi.org/10.1016/S0032-3861(97)00184-5
  2. W. D. Cook, "Thermal aspects of the kinetics of dimethacrylate photopolymerization", Polymer, Vol. 33, pp. 2152-2161, 1992. https://doi.org/10.1016/0032-3861(92)90882-W
  3. P. E. M. Allen, D. J. Bennett, S. Hagias, A. M. Hounslow, G. S. Ross, G. P. Simon, D. R. G. Williams, and E. H. Williams, "The radical polymerization of dimethacrylate monomers-the use of NMR spectrometry to follow the development of network structure", Eur. Polym. J., Vol. 25, pp. 785-789, 1989. https://doi.org/10.1016/0014-3057(89)90045-1
  4. G. P. Simon, P. E. M. Allen, D. J. Bennett, D. R. G. Williams, and E. H. Williams, "Nature of residual unsaturation during cure of dimethacrylates examined by CPPEMAS carbon-13 NMR and simulation using a kinetic gelation model", Macromolecules, Vol. 22, pp. 3555-3561, 1989. https://doi.org/10.1021/ma00199a010
  5. Y. Choe and B. K. Ryu, "Photopolymerization of reactive oligomers and Methacrylate/SBS blends", Polymer (Korea), Vol. 27, pp. 421-428, 2003.
  6. G. Smets, L. Convent, and X. Van der Borght, "Branching and graftcopolymerization of polyethyl-${\alpha}$-chloroacrylate", Macromol. Chem. Phys., Vol. 23, pp. 162-174, 1957. https://doi.org/10.1002/macp.1957.020230113
  7. R. J. Ceresa, "The physico-chemical synthesis of block copolymers", Polymer, Vol. 1, pp. 397-399, 1960. https://doi.org/10.1016/0032-3861(60)90049-5
  8. H. A. Dieu, "Etudes des solutions d'alcool polyvinylique", J. Polym. Sci. A Polym. Chem., Vol. 12, pp. 417-438, 1954.
  9. J. A. Hick and H. W. Melville, "A flow method for the synthesis of 'Block' copolymers", Nature, Vol. 171, pp. 300-301, 1953. https://doi.org/10.1038/171300a0
  10. S. Yamago, K. Iida, M. Nakajima, and J.-I. Yoshida, "Practical protocols for organotellurium-mediated living radical polymerization by in situ generated initiators from AIBN and ditellurides", Macromolecules, Vol. 36, pp. 3793-3796, 2003. https://doi.org/10.1021/ma034211a
  11. S. Washiro, M. Yoshizawa, H. Nakajima, and H. Ohno, "Highly ion conductive flexible films composed of network polymers based on polymerizable ionic liquids", Polymer, Vol. 45, pp. 1577-1582, 2004. https://doi.org/10.1016/j.polymer.2004.01.003
  12. K. Scharffetter-Kochanek, M. Wlaschek, P. Brenneisen, M. Schauen, R. Blaudschun, and J. Wenk, "UV-induced reactive oxygen species in photocarcinogenesis and photoaging", Biol. Chem., Vol. 378, pp. 1247-1258, 1997.
  13. E. Kvam and R. M. Tyrrell, "Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation", Carcinogenesis, Vol. 18, pp. 2379-2384, 1997. https://doi.org/10.1093/carcin/18.12.2379
  14. F. R. de Gruijl, "Photocarcinogenesis: UVA vs UVB", Methods Enzymol., Vol. 319, pp. 359-366, 2000.
  15. W. S. Duke-Elder, "The pathological action of light upon the eye", The Lancet, Vol. 207, pp. 1137-1141, 1926. https://doi.org/10.1016/S0140-6736(00)95309-1
  16. G. T. Wondrak, M. J. Roberts, M. K. Jacobson, and E. L. Jacobson, "3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells", J. Biol. Chem., Vol. 279, pp. 30009-30020, 2004. https://doi.org/10.1074/jbc.M404379200
  17. A. Y. Sung, T. H. Kim, and J. I. Kong, "Polymerization of hydrogel contact lens with high oxygen transmissibility", Journal of Korean Ophthalmic Optics Society, Vol. 11, pp. 49-53, 2006.
  18. S. A. Cho, S. Y. Park, T. H. Kim, and A. Y. Sung, "Characterization of physical properties of hydrogel contact lens materials containing 1,4-butanediol and (${\pm}$)-1,2,4-butanetriol for wettability improvement", The Korean Journal of Vision Science, Vol. 14, pp. 69-76, 2012.
  19. M. J. Lee, A. Y. Sung, and T. H. Kim, "Influence of wetting agents on physical properties of soft contact lens", Journal of Korean Ophthalmic Optics Society, Vol. 19, pp. 43-49, 2014. https://doi.org/10.14479/jkoos.2014.19.1.43
  20. D. H. Kim, A. Y. Sung, and T. H. Kim, "Antibacterial and characterization of high performance soft contact lens using fluoro- and carboxy-substituted pyridine as additive", Korean J. Vis. Sci. Vol. 16, pp. 89-97, 2014.
  21. T. H. Kim, K. H. Ye, and A. Y. Sung, "UV-Blocking effect of ophthalmic material containing benzophenone", Journal of the Korean Chemical Society, Vol. 53, pp. 391-394, 2009. https://doi.org/10.5012/jkcs.2009.53.3.391
  22. D. H. Kim and A. Y. Sung, "Application of hydroxylsubstituted benzophenone group for UV-block soft contact lens", The Korean Journal of Vision Science, Vol. 17, pp. 1-12, 2015.
  23. Y. Gan, J. Yin, and X. Jiana, "Self-wrinkling induced by the photopolymerization and self-assembly of fluorinated polymer at air/liquid interface", J. Mater. Chem. A, Vol. 2, pp. 18574-18582, 2014. https://doi.org/10.1039/C4TA03811H
  24. Y. S. Suh and S. H. Kim, "UV-cut effects of cotton fabrics treated with UV absorbents", J. Korea Society of Clothing and Texiles, Vol. 18, pp. 622-627, 1994.