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Metronomic chemotherapy with capecitabine for metastatic colorectal cancer in very elderly patients

  • Jung, Yun Hwa (Division of Medical Oncology, Department of Internal Medicine, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Won Jik (Division of Medical Oncology, Department of Internal Medicine, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea) ;
  • Byeon, Jae Ho (Division of Medical Oncology, Department of Internal Medicine, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, In Kyu (Department of Surgery, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea) ;
  • Han, Chi Wha (Department of Internal Medicine, Cheju Halla General Hospital) ;
  • Woo, In Sook (Division of Medical Oncology, Department of Internal Medicine, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea)
  • Received : 2015.03.02
  • Accepted : 2015.06.17
  • Published : 2017.09.01

Abstract

Keywords

References

  1. Dotan E, Browner I, Hurria A, Denlinger C. Challenges in the management of older patients with colon cancer. J Natl Compr Canc Netw 2012;10:213-224. https://doi.org/10.6004/jnccn.2012.0020
  2. Feliu J, Escudero P, Llosa F, et al. Capecitabine as firstline treatment for patients older than 70 years with metastatic colorectal cancer: an oncopaz cooperative group study. J Clin Oncol 2005;23:3104-3111. https://doi.org/10.1200/JCO.2005.06.035
  3. Sun W. Evolution of capecitabine dosing in colorectal cancer. Clin Colorectal Cancer 2010;9:31-39. https://doi.org/10.3816/CCC.2010.n.004
  4. Andre N, Carre M, Pasquier E. Metronomics: towards personalized chemotherapy? Nat Rev Clin Oncol 2014;11:413-431. https://doi.org/10.1038/nrclinonc.2014.89
  5. Nannini M, Nobili E, Di Cicilia R, et al. To widen the setting of cancer patients who could benefit from metronomic capecitabine. Cancer Chemother Pharmacol 2009;64:189-193. https://doi.org/10.1007/s00280-009-0930-z

Cited by

  1. Clinical characteristics and treatment propensity in elderly patients aged over 80 years with colorectal cancer vol.33, pp.6, 2018, https://doi.org/10.3904/kjim.2016.181