The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Prevalence and risk factors for reduced pulmonary function in diabetic patients: The Korea National Health and Nutrition Examination Survey

  • Kim, Hee Yeon (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Sohn, Tae Seo (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Seok, Hannah (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Yeo, Chang Dong (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Kim, Young Soo (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Song, Jae Yen (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Young Bok (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Dong-Hee (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Jae-Im (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Tae-Kyu (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Jeong, Seong Cheol (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Hong, Mihee (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea) ;
  • Chae, Hiun Suk (Epidemiology Study Cluster of Uijeongbu St. Mary's Hospital, College of Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea)
  • Received : 2016.02.15
  • Accepted : 2016.05.03
  • Published : 2017.07.01
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Abstract

Background/Aims: An association between reduced pulmonary function and diabetes has been observed. Our aim was to evaluate the prevalence and risk factors associated with reduced pulmonary function in diabetic patients. Methods: We analyzed data from the Korea National Health and Nutrition Examination Survey 2011 to 2013. The study population included data from 8,784 participants (including 1,431 diabetics) aged ${\geq}40years$. Reduced pulmonary function was defined as patients with restrictive (forced expiratory volume in 1 second/forced vital capacity $[FEV_1/FVC]{\geq}0.7$ and FVC < 80% of predicted value) or obstructive ($FEV_1/FVC$ < 0.7) patterns. Results: Subjects with diabetes had a higher prevalence of restrictive (18.4% vs. 9.4%, p < 0.001) and obstructive impairments (20% vs. 12.6%, p < 0.001) than those without diabetes. The adjusted odds ratios (aORs) (95% confidence interval [CI]) for obstructive and restrictive pulmonary impairment were 0.91 (0.75 to 1.11) and 1.57 (1.30 to 1.89), respectively. In the diabetes population, age (aOR, 1.04; 95% CI, 1.02 to 1.06), male sex (aOR, 1.40; 95% CI, 1.04 to 1.88), and body mass index (aOR, 1.15; 95% CI, 1.10 to 1.21) were independently associated with restrictive pulmonary impairment. Age (aOR, 1.12; 95% CI, 1.09 to 1.14), male sex (aOR, 4.24; 95% CI, 2.42 to 7.44), and smoking at any point (ever-smoker: aOR, 1.96; 95% CI, 1.16 to 3.33) were independent risk factors for obstructive pulmonary impairment in diabetics. Diabetes duration or glycated hemoglobin had no association with pulmonary impairment in diabetes. Conclusions: Subjects with diabetes had a higher risk of restrictive pulmonary impairment than those without diabetes after adjusting for confounding factors. Older age, male sex, body mass index, and smoking were associated with reduced lung function in diabetes.

Keywords

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