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Comment on "Hypogonadotrophic hypogonadism due to a mutation in the luteinizing hormone β-subunit gene"

Valdes-Socin, Hernan (Department of Endocrinology, University Hospital Center of Liege, University of Liege) ;
Daly, Adrian F. (Department of Endocrinology, University Hospital Center of Liege, University of Liege) ;
Beckers, Albert (Department of Endocrinology, University Hospital Center of Liege, University of Liege)

Song JW, Hwang HJ, Lee CM, et al. Hypogonadotrophic hypogonadism due to a mutation in the luteinizing hormone $\beta$-subunit gene. Korean J Intern Med 2017 Jan 16 [Epub]. https://doi.org/10.3904/kjim.2015.373.
Bougneres P, Francois M, Pantalone L, et al. Effects of an early postnatal treatment of hypogonadotropic hypogonadism with a continuous subcutaneous infusion of recombinant follicle-stimulating hormone and luteinizing hormone. J Clin Endocrinol Metab 2008;93:2202-2205. https://doi.org/10.1210/jc.2008-0121
Valdes-Socin H, Salvi R, Daly AF, et al. Hypogonadism in a patient with a mutation in the luteinizing hormone beta-subunit gene. N Engl J Med 2004;351:2619-2625. https://doi.org/10.1056/NEJMoa040326
Valdes-Socin H, Salvi R, Thiry A, et al. Testicular effects of isolated luteinizing hormone deficiency and reversal by long-term human chorionic gonadotropin treatment. J Clin Endocrinol Metab 2009;94:3-4. https://doi.org/10.1210/jc.2008-1584
Potorac I, Rivero-Muller A, Trehan A, et al. A vital region for human glycoprotein hormone trafficking revealed by an LHB mutation. J Endocrinol 2016;231:197-207. https://doi.org/10.1530/JOE-16-0384

Homozygous nonsense mutation Trp28X in the LHB gene causes male hypogonadism vol.35, pp.5, 2017, https://doi.org/10.1007/s10815-018-1133-5
Male hypogonadism caused by a homozygous missense mutation of the LHB gene vol.36, pp.6, 2017, https://doi.org/10.3904/kjim.2021.086