References
- Bae, K.H., Kwon, Y.D., Shin, H.C., Hwang, M.S., Ryu, E.H., Park, K.S., Yang, H.Y., Lee, D.K., Lee, Y., Park, J., et al. (2003). Human zinc fingers as building blocks in the construction of artificial transcription factors. Nat. Biotechnol. 21, 275-280. https://doi.org/10.1038/nbt796
- Bailus, B.J., and Segal, D.J. (2014). The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disorders. BMC Neurosci. 15, 76. https://doi.org/10.1186/1471-2202-15-76
- Beerli, R.R., and Barbas, C.F., 3rd (2002). Engineering polydactyl zincfinger transcription factors. Nat. Biotechnol. 20, 135-141. https://doi.org/10.1038/nbt0202-135
- Beerli, R.R., Segal, D.J., Dreier, B., and Barbas, C.F., 3rd (1998). Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks. Proc. Natl. Acad. Sci. USA 95, 14628-14633. https://doi.org/10.1073/pnas.95.25.14628
- Beerli, R.R., Dreier, B., and Barbas, C.F., 3rd (2000). Positive and negative regulation of endogenous genes by designed transcription factors. Proc. Natl. Acad. Sci. USA 97, 1495-1500. https://doi.org/10.1073/pnas.040552697
- Bhakta, M.S., and Segal, D.J. (2010). The generation of zinc finger proteins by modular assembly. Methods Mol. Biol. 649, 3-30.
- Boch, J., Scholze, H., Schornack, S., Landgraf, A., Hahn, S., Kay, S., Lahaye, T., Nickstadt, A., and Bonas, U. (2009). Breaking the code of DNA binding specificity of TAL-type III effectors. Science 326, 1509-1512. https://doi.org/10.1126/science.1178811
- Camenisch, T.D., Brilliant, M.H., and Segal, D.J. (2008). Critical parameters for genome editing using zinc finger nucleases. Mini Rev. Med. Chem. 8, 669-676. https://doi.org/10.2174/138955708784567458
- Cermak, T., Doyle, E.L., Christian, M., Wang, L., Zhang, Y., Schmidt, C., Baller, J.A., Somia, N.V., Bogdanove, A.J., and Voytas, D.F. (2011). Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res. 39, e82. https://doi.org/10.1093/nar/gkr218
- Curtin, S.J., Zhang, F., Sander, J.D., Haun, W.J., Starker, C., Baltes, N.J., Reyon, D., Dahlborg, E.J., Goodwin, M.J., Coffman, A.P., et al. (2011). Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases. Plant Physiol. 156, 466-473. https://doi.org/10.1104/pp.111.172981
- Deng, D., Yan, C., Pan, X., Mahfouz, M., Wang, J., Zhu, J.K., Shi, Y., and Yan, N. (2012). Structural basis for sequence-specific recognition of DNA by TAL effectors. Science 335, 720-723. https://doi.org/10.1126/science.1215670
- Dreier, B., Segal, D.J., and Barbas, C.F., 3rd (2000). Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains. J. Mol. Biol. 303, 489-502. https://doi.org/10.1006/jmbi.2000.4133
- Dreier, B., Beerli, R.R., Segal, D.J., Flippin, J.D., and Barbas, C.F., 3rd (2001). Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors. J. Biol. Chem. 276, 29466-29478. https://doi.org/10.1074/jbc.M102604200
- Dreier, B., Fuller, R.P., Segal, D.J., Lund, C.V., Blancafort, P., Huber, A., Koksch, B., and Barbas, C.F., 3rd (2005). Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors. J. Biol. Chem. 280, 35588-35597. https://doi.org/10.1074/jbc.M506654200
- Engler, C., Kandzia, R., and Marillonnet, S. (2008). A one pot, one step, precision cloning method with high throughput capability. PLoS One 3, e3647. https://doi.org/10.1371/journal.pone.0003647
- Feng, X., Bednarz, A.L., and Colloms, S.D. (2010). Precise targeted integration by a chimaeric transposase zinc-finger fusion protein. Nucleic Acids Res. 38, 1204-1216. https://doi.org/10.1093/nar/gkp1068
- Gaj, T., Guo, J., Kato, Y., Sirk, S.J., and Barbas, C.F., 3rd (2012). Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. Nat. Methods 9, 805-807. https://doi.org/10.1038/nmeth.2030
- Gaj, T., Gersbach, C.A., and Barbas, C.F., 3rd (2013a). ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol. 31, 397-405. https://doi.org/10.1016/j.tibtech.2013.04.004
- Gaj, T., Mercer, A.C., Sirk, S.J., Smith, H.L., and Barbas, C.F., 3rd (2013b). A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells. Nucleic Acids Res. 41, 3937-3946. https://doi.org/10.1093/nar/gkt071
- Gaj, T., Liu, J., Anderson, K.E., Sirk, S.J., and Barbas, C.F., 3rd (2014a). Protein delivery using Cys2-His2 zinc-finger domains. ACS Chem. Biol. 9, 1662-1667. https://doi.org/10.1021/cb500282g
- Gaj, T., Sirk, S.J., Tingle, R.D., Mercer, A.C., Wallen, M.C., and Barbas, C.F., 3rd (2014b). Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign. J. Am. Chem. Soc. 136, 5047-5056. https://doi.org/10.1021/ja4130059
- Gersbach, C.A., Gaj, T., and Barbas, C.F., 3rd (2014). Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. Acc. Chem. Res. 47, 2309-2318. https://doi.org/10.1021/ar500039w
- Ghosh, I., Stains, C.I., Ooi, A.T., and Segal, D.J. (2006). Direct detection of double-stranded DNA: Molecular methods and applications for DNA diagnostics. Mol. Biosyst. 2, 551-560. https://doi.org/10.1039/b611169f
- Gordley, R.M., Smith, J.D., Graslund, T., and Barbas, C.F., 3rd (2007). Evolution of programmable zinc finger-recombinases with activity in human cells. J. Mol. Biol. 367, 802-813. https://doi.org/10.1016/j.jmb.2007.01.017
- Gordley, R.M., Gersbach, C.A., and Barbas, C.F., 3rd (2009). Synthesis of programmable integrases. Proc. Natl. Acad. Sci. USA 106, 5053-5058. https://doi.org/10.1073/pnas.0812502106
- Graslund, T., Li, X., Magnenat, L., Popkov, M., and Barbas, C.F., 3rd (2005). Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease. J. Biol. Chem. 280, 3707-3714. https://doi.org/10.1074/jbc.M406809200
- Grindley, N.D., Whiteson, K.L., and Rice, P.A. (2006). Mechanisms of site-specific recombination. Annu. Rev. Biochem. 75, 567-605. https://doi.org/10.1146/annurev.biochem.73.011303.073908
- Hockemeyer, D., Wang, H., Kiani, S., Lai, C.S., Gao, Q., Cassady, J.P., Cost, G.J., Zhang, L., Santiago, Y., Miller, J.C., et al. (2011). Genetic engineering of human pluripotent cells using TALE nucleases. Nat. Biotechnol. 29, 731-734. https://doi.org/10.1038/nbt.1927
- Holt, N., Wang, J., Kim, K., Friedman, G., Wang, X., Taupin, V., Crooks, G.M., Kohn, D.B., Gregory, P.D., Holmes, M.C., et al. (2010). Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo. Nat. Biotechnol. 28, 839-847. https://doi.org/10.1038/nbt.1663
- Jiang, F., and Doudna, J.A. (2015). The structural biology of CRISPRCas systems. Curr. Opin. Struct. Biol. 30, 100-111. https://doi.org/10.1016/j.sbi.2015.02.002
- Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J.A., and Charpentier, E. (2012). A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821. https://doi.org/10.1126/science.1225829
- Joung, J.K., Ramm, E.I., and Pabo, C.O. (2000). A bacterial twohybrid selection system for studying protein-DNA and protein-protein interactions. Proc. Natl. Acad. Sci. USA 97, 7382-7387. https://doi.org/10.1073/pnas.110149297
- Kim, M.S., Stybayeva, G., Lee, J.Y., Revzin, A., and Segal, D.J. (2011). A zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applications. Nucleic Acids Res. 39, e29. https://doi.org/10.1093/nar/gkq1214
- Kolb, A.F., Coates, C.J., Kaminski, J.M., Summers, J.B., Miller, A.D., and Segal, D.J. (2005). Site-directed genome modification: nucleic acid and protein modules for targeted integration and gene correction. Trends Biotechnol. 23, 399-406. https://doi.org/10.1016/j.tibtech.2005.06.005
- Li, H., Haurigot, V., Doyon, Y., Li, T., Wong, S.Y., Bhagwat, A.S., Malani, N., Anguela, X.M., Sharma, R., Ivanciu, L., et al. (2011a). In vivo genome editing restores haemostasis in a mouse model of haemophilia. Nature 475, 217-221. https://doi.org/10.1038/nature10177
- Li, T., Huang, S., Zhao, X., Wright, D.A., Carpenter, S., Spalding, M.H., Weeks, D.P., and Yang, B. (2011b). Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes. Nucleic Acids Res. 39, 6315-6325. https://doi.org/10.1093/nar/gkr188
- Li, L., Krymskaya, L., Wang, J., Henley, J., Rao, A., Cao, L.F., Tran, C.A., Torres-Coronado, M., Gardner, A., Gonzalez, N., et al. (2013). Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases. Mol. Ther. 21, 1259-1269. https://doi.org/10.1038/mt.2013.65
- Maeder, M.L., Thibodeau-Beganny, S., Osiak, A., Wright, D.A., Anthony, R.M., Eichtinger, M., Jiang, T., Foley, J.E., Winfrey, R.J., Townsend, J.A., et al. (2008). Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol. Cell 31, 294-301. https://doi.org/10.1016/j.molcel.2008.06.016
- Maeder, M.L., Thibodeau-Beganny, S., Sander, J.D., Voytas, D.F., and Joung, J.K. (2009). Oligomerized pool engineering (OPEN): an 'opensource' protocol for making customized zinc-finger arrays. Nat. Protoc. 4, 1471-1501. https://doi.org/10.1038/nprot.2009.98
- Maeder, M.L., Linder, S.J., Reyon, D., Angstman, J.F., Fu, Y., Sander, J.D., and Joung, J.K. (2013). Robust, synergistic regulation of human gene expression using TALE activators. Nat. Methods 10, 243-245. https://doi.org/10.1038/nmeth.2366
- Mahfouz, M.M., Li, L., Piatek, M., Fang, X., Mansour, H., Bangarusamy, D.K., and Zhu, J.K. (2012). Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein. Plant Mol. Biol. 78, 311-321. https://doi.org/10.1007/s11103-011-9866-x
- Mak, A.N., Bradley, P., Cernadas, R.A., Bogdanove, A.J., and Stoddard, B.L. (2012). The crystal structure of TAL effector PthXo1 bound to its DNA target. Science 335, 716-719. https://doi.org/10.1126/science.1216211
- Mak, A.N., Bradley, P., Bogdanove, A.J., and Stoddard, B.L. (2013). TAL effectors: function, structure, engineering and applications. Curr. Opin. Struct. Biol. 23, 93-99. https://doi.org/10.1016/j.sbi.2012.11.001
- Mercer, A.C., Gaj, T., Fuller, R.P., and Barbas, C.F., 3rd (2012). Chimeric TALE recombinases with programmable DNA sequence specificity. Nucleic Acids Res. 40, 11163-11172. https://doi.org/10.1093/nar/gks875
- Miller, J.C., Tan, S., Qiao, G., Barlow, K.A., Wang, J., Xia, D.F., Meng, X., Paschon, D.E., Leung, E., Hinkley, S.J., et al. (2011). A TALE nuclease architecture for efficient genome editing. Nat. Biotechnol. 29, 143-148. https://doi.org/10.1038/nbt.1755
- Moore, M., Klug, A., and Choo, Y. (2001). Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units. Proc. Natl. Acad. Sci. USA 98, 1437-1441. https://doi.org/10.1073/pnas.98.4.1437
- Morbitzer, R., Elsaesser, J., Hausner, J., and Lahaye, T. (2011). Assembly of custom TALE-type DNA binding domains by modular cloning. Nucleic Acids Res. 39, 5790-5799. https://doi.org/10.1093/nar/gkr151
- Moscou, M.J., and Bogdanove, A.J. (2009). A simple cipher governs DNA recognition by TAL effectors. Science 326, 1501. https://doi.org/10.1126/science.1178817
- Mussolino, C., Morbitzer, R., Lutge, F., Dannemann, N., Lahaye, T., and Cathomen, T. (2011). A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity. Nucleic Acids Res. 39, 9283-9293. https://doi.org/10.1093/nar/gkr597
- Ooi, A.T., Stains, C.I., Ghosh, I., and Segal, D.J. (2006). Sequenceenabled reassembly of beta-lactamase (SEER-LAC): a sensitive method for the detection of double-stranded DNA. Biochemistry 45, 3620-3625. https://doi.org/10.1021/bi0517032
- Ousterout, D.G., Perez-Pinera, P., Thakore, P.I., Kabadi, A.M., Brown, M.T., Qin, X., Fedrigo, O., Mouly, V., Tremblay, J.P., and Gersbach, C.A. (2013). Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients. Mol. Ther. 21, 1718-1726. https://doi.org/10.1038/mt.2013.111
- Owens, J.B., Urschitz, J., Stoytchev, I., Dang, N.C., Stoytcheva, Z., Belcaid, M., Maragathavally, K.J., Coates, C.J., Segal, D.J., and Moisyadi, S. (2012). Chimeric piggyBac transposases for genomic targeting in human cells. Nucleic Acids Res. 40, 6978-6991. https://doi.org/10.1093/nar/gks309
- Owens, J.B., Mauro, D., Stoytchev, I., Bhakta, M.S., Kim, M.S., Segal, D.J., and Moisyadi, S. (2013). Transcription activator like effector (TALE)-directed piggyBac transposition in human cells. Nucleic Acids Res. 41, 9197-9207. https://doi.org/10.1093/nar/gkt677
- Perez, E.E., Wang, J., Miller, J.C., Jouvenot, Y., Kim, K.A., Liu, O., Wang, N., Lee, G., Bartsevich, V.V., Lee, Y.L., et al. (2008). Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat. Biotechnol. 26, 808-816. https://doi.org/10.1038/nbt1410
- Perez-Pinera, P., Ousterout, D.G., Brunger, J.M., Farin, A.M., Glass, K.A., Guilak, F., Crawford, G.E., Hartemink, A.J., and Gersbach, C.A. (2013). Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat. Methods 10, 239-242. https://doi.org/10.1038/nmeth.2361
- Reyon, D., Tsai, S.Q., Khayter, C., Foden, J.A., Sander, J.D., and Joung, J.K. (2012). FLASH assembly of TALENs for high-throughput genome editing. Nat. Biotechnol. 30, 460-465. https://doi.org/10.1038/nbt.2170
- Reyon, D., Maeder, M.L., Khayter, C., Tsai, S.Q., Foley, J.E., Sander, J.D., and Joung, J.K. (2013). Engineering customized TALE nucleases (TALENs) and TALE transcription factors by fast ligation-based automatable solid-phase high-throughput (FLASH) assembly. Curr. Protoc. Mol. Biol. Chapter 12, Unit 12 16.
- Rogers, J.M., Barrera, L.A., Reyon, D., Sander, J.D., Kellis, M., Joung, J.K., and Bulyk, M.L. (2015). Context influences on TALE-DNA binding revealed by quantitative profiling. Nat. Commun. 6, 7440. https://doi.org/10.1038/ncomms8440
- Sander, J.D., Cade, L., Khayter, C., Reyon, D., Peterson, R.T., Joung, J.K., and Yeh, J.R. (2011). Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat. Biotechnol. 29, 697-698. https://doi.org/10.1038/nbt.1934
- Sanjana, N.E., Cong, L., Zhou, Y., Cunniff, M.M., Feng, G., and Zhang, F. (2012). A transcription activator-like effector toolbox for genome engineering. Nat. Protoc. 7, 171-192. https://doi.org/10.1038/nprot.2011.431
- Sebastiano, V., Maeder, M.L., Angstman, J.F., Haddad, B., Khayter, C., Yeo, D.T., Goodwin, M.J., Hawkins, J.S., Ramirez, C.L., Batista, L.F., et al. (2011). In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells 29, 1717-1726. https://doi.org/10.1002/stem.718
- Segal, D.J., and Meckler, J.F. (2013). Genome engineering at the dawn of the golden age. Annu. Rev. Genomics Hum. Genet. 14, 135-158. https://doi.org/10.1146/annurev-genom-091212-153435
- Segal, D.J., Dreier, B., Beerli, R.R., and Barbas, C.F., 3rd (1999). Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences. Proc. Natl. Acad. Sci. USA 96, 2758-2763. https://doi.org/10.1073/pnas.96.6.2758
- Segal, D.J., Beerli, R.R., Blancafort, P., Dreier, B., Effertz, K., Huber, A., Koksch, B., Lund, C.V., Magnenat, L., Valente, D., et al. (2003). Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins. Biochemistry 42, 2137-2148. https://doi.org/10.1021/bi026806o
- Segal, D.J., Goncalves, J., Eberhardy, S., Swan, C.H., Torbett, B.E., Li, X., and Barbas, C.F., 3rd (2004). Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor. J. Biol. Chem. 279, 14509-14519. https://doi.org/10.1074/jbc.M400349200
- Segal, D.J., Crotty, J.W., Bhakta, M.S., Barbas, C.F., 3rd, and Horton, N.C. (2006). Structure of Aart, a designed six-finger zinc finger peptide, bound to DNA. J. Mol. Biol. 363, 405-421. https://doi.org/10.1016/j.jmb.2006.08.016
- Smith, M.C., and Thorpe, H.M. (2002). Diversity in the serine recombinases. Mol. Microbiol. 44, 299-307. https://doi.org/10.1046/j.1365-2958.2002.02891.x
- Soldner, F., Laganiere, J., Cheng, A.W., Hockemeyer, D., Gao, Q., Alagappan, R., Khurana, V., Golbe, L.I., Myers, R.H., Lindquist, S., et al. (2011). Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 146, 318-331. https://doi.org/10.1016/j.cell.2011.06.019
- Sun, N., Liang, J., Abil, Z., and Zhao, H. (2012). Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease. Mol. Biosyst. 8, 1255-1263. https://doi.org/10.1039/c2mb05461b
- Urnov, F.D., Rebar, E.J., Holmes, M.C., Zhang, H.S., and Gregory, P.D. (2010). Genome editing with engineered zinc finger nucleases. Nat. Rev. Genet. 11, 636-646. https://doi.org/10.1038/nrg2842
- Voigt, K., Gogol-Doring, A., Miskey, C., Chen, W., Cathomen, T., Izsvak, Z., and Ivics, Z. (2012). Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains. Mol. Ther. 20, 1852-1862. https://doi.org/10.1038/mt.2012.126
- Wilber, A., Tschulena, U., Hargrove, P.W., Kim, Y.S., Persons, D.A., Barbas, C.F., 3rd, and Nienhuis, A.W. (2010). A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts. Blood 115, 3033-3041. https://doi.org/10.1182/blood-2009-08-240556
- Wu, H., Yang, W.P., and Barbas, C.F., 3rd (1995). Building zinc fingers by selection: toward a therapeutic application. Proc. Natl. Acad. Sci. USA 92, 344-348. https://doi.org/10.1073/pnas.92.2.344
- Yusa, K., Rashid, S.T., Strick-Marchand, H., Varela, I., Liu, P.Q., Paschon, D.E., Miranda, E., Ordonez, A., Hannan, N.R., Rouhani, F.J., et al. (2011). Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells. Nature 478, 391-394. https://doi.org/10.1038/nature10424
- Zhang, F., Cong, L., Lodato, S., Kosuri, S., Church, G.M., and Arlotta, P. (2011). Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat. Biotechnol. 29, 149-153. https://doi.org/10.1038/nbt.1775
- Zou, J., Mali, P., Huang, X., Dowey, S.N., and Cheng, L. (2011). Sitespecific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood 118, 4599-4608. https://doi.org/10.1182/blood-2011-02-335554
Cited by
- The conserved basic residues and the charged amino acid residues at the α-helix of the zinc finger motif regulate the nuclear transport activity of triple C2H2 zinc finger proteins vol.13, pp.1, 2018, https://doi.org/10.1371/journal.pone.0191971
- Zinc finger domains as therapeutic targets for metal-based compounds – an update pp.1756-591X, 2018, https://doi.org/10.1039/C8MT00262B
- Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip vol.143, pp.17, 2018, https://doi.org/10.1039/C8AN00395E
- The Arms Race Between KRAB-Zinc Finger Proteins and Endogenous Retroelements and Its Impact on Mammals vol.53, pp.1, 2017, https://doi.org/10.1146/annurev-genet-112618-043717
- Chimerization Enables Gene Synthesis and Lentiviral Delivery of Customizable TALE-Based Effectors vol.21, pp.3, 2017, https://doi.org/10.3390/ijms21030795
- Recent advances in genome editing of stem cells for drug discovery and therapeutic application vol.209, pp.None, 2017, https://doi.org/10.1016/j.pharmthera.2020.107501
- Induced Methylation in Plants as a Crop Improvement Tool: Progress and Perspectives vol.10, pp.10, 2017, https://doi.org/10.3390/agronomy10101484
- Delivery technologies for T cell gene editing: Applications in cancer immunotherapy vol.67, pp.None, 2017, https://doi.org/10.1016/j.ebiom.2021.103354
- Genomics in medicine: A new era in medicine vol.11, pp.5, 2017, https://doi.org/10.5662/wjm.v11.i5.231
- Application of Engineered Zinc Finger Proteins Immobilized on Paramagnetic Beads for Multiplexed Detection of Pathogenic DNA vol.31, pp.9, 2017, https://doi.org/10.4014/jmb.2106.06057