Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Association between Quality of Life and Symptom Severity in Obsessive-Compulsive Disorder Patients Using EQ-5D

EQ-5D를 이용한 강박장애 환자의 삶의 질과 증상 중증도의 연관성 연구

  • Kim, Sung Nyun (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Moon, Woori (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Han, Jaewook (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Lee, Junhee (Department of Neuropsychiatry, Seoul National University Hospital)
  • 김성년 (서울대학교병원 정신건강의학과) ;
  • 문우리 (서울대학교병원 정신건강의학과) ;
  • 한재욱 (서울대학교병원 정신건강의학과) ;
  • 이준희 (서울대학교병원 정신건강의학과)
  • Received : 2017.05.21
  • Accepted : 2017.05.31
  • Published : 2017.08.31
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Abstract

Objectives Obsessive-compulsive disorder (OCD) is a disabling psychiatric disorder, and more attention is recently paid on the quality of life (QoL) in OCD patients. The Euro-QoL-5D (EQ-5D) is a widely used self-report to calculate a single score which represents 'health utilities'. The aim of this study was to assess the health-related QoL for patients with OCD using the EQ-5D and to examine the relationship between health-related QoL and symptom severity. Methods Seventy-three patients with a Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnosis of OCD were recruited from the outpatient clinic in Seoul National University Hospital. Symptom severity was assessed using the Yale-Brown Obsessive-Compulsive Scale (YBOCS), and QoL was assessed with the EQ-5D-5L questionnaire. Using Korean valuation study, a single score of QoL was calculated. Results Most of the OCD patients were relatively young (< 45 years) with the mean YBOCS total score of 19.33. The mean EQ-5D score was 0.71 and significantly correlated with symptom severity (r = -0.483, p < 0.001). 25% of the EQ-5D score was predicted by the YBOCS total score (b = -0.011, p < 0.001) by regression analysis. Conclusions OCD patients suffer from lower health-related QoL and QoL significantly decreased as symptom severity increased. The results of the EQ-5D would enable further studies on QoL comparison across medical disease and mental disorders.

Keywords

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