한국환경보건학회지 (Journal of Environmental Health Sciences)

  • 제43권4호
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  • Pages.280-297
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  • 2017
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  • 1738-4087(pISSN)
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  • 2233-8616(eISSN)
한국환경보건학회 (Korean Society of Environmental Health)
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시설 고추와 오이, 과수 재배 농업인의 유기인계 및 피레스로이드 살충제 노출 수준과 관련 농작업 특성

Exposure Level to Organophosphate and Pyrethroid Pesticides and Related Agricultural Factors in Chili and Cucumber Cultivation among Greenhouse and Orchard Farmers

  • 김신아 (단국대학교병원 농업안전보건센터) ;
  • 노상철 (단국대학교 의과대학 직업환경의학교실)
  • Kim, Shinah (Center for Farmers' Safety and Health, Dankook University Hospital) ;
  • Roh, Sangchul (Department of Occupational and Environment Medicine, College of Medicine, Dankook University)
  • 투고 : 2017.07.21
  • 심사 : 2017.08.19
  • 발행 : 2017.08.28
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초록

Objectives: We assessed pesticide exposure levels according to cultivation and crop type and investigated agricultural factors related to exposure. Methods: The participants, 341 male and 127 female farmers, were divided into three groups by cultivation crop type: chili greenhouse, cucumber greenhouse, and orchard. We collected questionnaires, socioeconomic characteristics and agricultural factors, and spot urine. Pesticide exposure was examined using four organophosphate and four pyrethroids urinary metabolites: dimethylphosphate, dimethylthiophosphate, diethylphosphate, diethylthiophosphate, Cis and Trans-3-(2-2dichlorovinyl)-2, 2-dimethylcyclopropane carboxylic acid, 3-phenoxybenzoic acid (3-PBA), Cis-3-(2-2dibrmovinyl)-2, and 2-dimethylcyclopropane carboxylic acid. Each metabolite was summed ${\Sigma}DAP$ and ${\Sigma}PY$ according to the chemical class. Results: Urinary metabolite detection rates and concentrations were similar between the greenhouse groups, but the orchard group was different. Similar 3-PBA detection rates were found in the three groups, but the geometric mean was very high in the orchard group compared to the two greenhouse groups. 3-PBA concentration in the orchard group was $4.11{\mu}g/g$ creatinine; the chili and cucumber greenhouse groups were 1.27 and $1.16{\mu}g/g$ creatinine, respectively. ${\Sigma}DAP$ was significantly associated with cultivation crop type and seasonal variation, but ${\Sigma}PY$ was not relevant. Conclusions: Our results suggest that cultivation and crop type may be correlated with different pesticide types and exposure levels. Furthermore, seasonal factors were related as potential factors influencing the level of organophosphate metabolites, but not for pyrethroid metabolites.

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참고문헌

  1. Roberts JR, Reigart JR. Recognition and Management of Pesticide Poisonings [Internet]. 6th ed. Washington, DC: U.S. Environmental Protection Agency; 2013. 212-238.
  2. Siemiatycki J, Richardson L, Straif K, Latreille B, Lakhani R, Campbell S, et al. Listing occupational carcinogens. Environ Health Perspect. 2004; 112(15): 1447-1459. https://doi.org/10.1289/ehp.7047
  3. Alavanja MCR, Bonner MR. Occupational Pesticide Exposures and Cancer Risk: A Review. J Toxicol Environ Heal Part B. 2012; 15(4): 238-263. https://doi.org/10.1080/10937404.2012.632358
  4. Barr DB, Bravo R, Weerasekera G, Caltabiano LM, Whitehead RD, Olsson A, et al. Concentrations of dialkyl phosphate metabolites of organophosphorus pesticides in the U.S. population. Environ Health Perspect. 2004; 112(2): 186-200. https://doi.org/10.1289/ehp.6503
  5. Cha ES, Jeong M, Lee WJ. Agricultural Pesticide Usage and Prioritization in South Korea. Vol. 19, Journal of Agromedicine. 2014; 19: 281-293. https://doi.org/10.1080/1059924X.2014.917349
  6. Lee WJ. Pesticides and Health in Public Health. Seoul: Korea University Press; 2013. 99-112.
  7. Hofmann JN, Beane Freeman LE, Lynch CF, Andreotti G, Thomas KW, Sandler DP, et al. The Biomarkers of Exposure and Effect in Agriculture (BEEA) Study: Rationale, design, methods, and participant characteristics. J Toxicol Environ Health A. 2015; 78(21-22): 1338-1347. https://doi.org/10.1080/15287394.2015.1091414
  8. Song JS, Ki S, Kwon D, Choi HS, Yu HY. Biological Monitoring of the Exposure Level of Organophosphorus and Pyrethroid Pesticides in Floriculture Workers and Florists. Korean J Pestic Sci. 2014; 18(1): 41-47. https://doi.org/10.7585/kjps.2014.18.1.41
  9. Song JS, Choi HS, Yu HY, Park BG, Kwon D. Evaluation of Exposure to Pyrethroid Pesticides according to Sprayer Type using Biological Monitoring. Korean J Pestic Sci. 2016; 20(4): 300-304. https://doi.org/10.7585/kjps.2016.20.4.300
  10. Kim JH, Kim J, Cha ES, Ko Y, Kim DH, Lee WJ. Work-related risk factors by severity for acute pesticide poisoning among male farmers in South Korea. Int J Environ Res Public Health. 2013; 10(3): 1100-1112. https://doi.org/10.3390/ijerph10031100
  11. Bravo R, Caltabiano LM, Weerasekera G, Whitehead RD, Fernandez C, Needham LL, et al. Measurement of dialkyl phosphate metabolites of organophosphorus pesticides in human urine using lyophilization with gas chromatography-tandem mass spectrometry and isotope dilution quantification. J Expo Anal Environ Epidemiol. 2004; 14(3): 249-259. https://doi.org/10.1038/sj.jea.7500322
  12. Schettgen T, Koch HM, Drexler H, Angerer J. New gas chromatographic-mass spectrometric method for the determination of urinary pyrethroid metabolites in environmental medicine. J Chromatogr B. 2002; 778(1): 121-130. https://doi.org/10.1016/S0378-4347(01)00452-2
  13. Ueyama J, Saito I, Kamijima M, Nakajima T, Gotoh M, Suzuki T, et al. Simultaneous determination of urinary dialkylphosphate metabolites of organophosphorus pesticides using gas chromatography- mass spectrometry. J Chromatogr B. 2006; 832(1): 58-66. https://doi.org/10.1016/j.jchromb.2005.12.030
  14. Arcury TA, Laurienti PJ, Chen H, Howard TD, Barr DB, Mora DC, et al. Organophosphate Pesticide Urinary Metabolites Among Latino Immigrants. J Occup Environ Med. 2016; 58(11): 1079- 1086. https://doi.org/10.1097/JOM.0000000000000875
  15. Prapamontol T, Sutan K, Laoyang S, Hongsibsong S, Lee G, Yano Y, et al. Cross validation of gas chromatography-flame photometric detection and gas chromatography-mass spectrometry methods for measuring dialkylphosphate metabolites of organophosphate pesticides in human urine. Int J Hyg Environ Health. 2014; 217(4-5): 554-566. https://doi.org/10.1016/j.ijheh.2013.10.005
  16. International Agency for Research on Cancer. IARC Monographs Volume 112: evaluation of five organophosphate insecticides and herbicides. Environ Heal. 2014; 112(1): 425-433.
  17. Park J. Environment and Health?: An Overview of Current Trends at WHO and OECD. J Environ Health Sci. 2013; 39(4): 299-311.
  18. Park C, Yu S Do. Status and Prospects of the Korean National Environmental Health Survey (KoNEHS). J Environ Health Sci. 2014; 40(1): 1-9.
  19. Schulz C, Angerer J, Ewers U, Heudorf U, Wilhelm M. Revised and new reference values for environmental pollutants in urine or blood of children in Germany derived from the German Environmental Survey on Children 2003-2006 (GerES IV). Int J Hyg Environ Health. 2009; 212(6): 637-647. https://doi.org/10.1016/j.ijheh.2009.05.003
  20. Korean Society of Environmental Health. 1st Korean National Environmental Health: Integrated analysis of survey data and preparation of national statistics. 2011.
  21. Osaka A, Ueyama J, Kondo T, Nomura H, Sugiura Y, Saito I, et al. Exposure characterization of three major insecticide lines in urine of young children in Japan-neonicotinoids, organophosphates, and pyrethroids. Environ Res. 2016; 147: 89-96. https://doi.org/10.1016/j.envres.2016.01.028
  22. Raymer JH, Studabaker W, Gardner M, Talton J, Quandt SA, Chen H, et al. Pesticide Exposures to Migrant Farmworkers in Eastern NC: Detection of metabolites in farmworker urine associated with housing violations and camp characteristics. Am J Ind Med. 2014; 57(3): 323-337. https://doi.org/10.1002/ajim.22284
  23. Ueyama J, Kimata A, Kamijima M, Hamajima N, Ito Y, Suzuki K, et al. Urinary excretion of 3-phenoxybenzoic acid in middle-aged and elderly general population of Japan. Environ Res. 2009; 109(2): 175-180. https://doi.org/10.1016/j.envres.2008.09.006
  24. Jang I, Kim H, Lee S, Choi K, Suh SJ. Analysis of Pesticide Applications on Apple Orchards in Geochang , Korea. Korean J Pestic Sci. 2015; 19(2): 93-100. https://doi.org/10.7585/kjps.2015.19.2.93
  25. Garfitt SJ, Jones K, Mason HJ, Cocker J. Exposure to the organophosphate diazinon: data from a human volunteer study with oral and dermal doses. Toxicol Lett. 2002; 134(1): 105-113. https://doi.org/10.1016/S0378-4274(02)00178-9
  26. Aprea C, Stridori A, Sciarra G. Analytical method for the determination of urinary 3-phenoxybenzoic acid in subjects occupationally exposed to pyrethroid insecticides. J Chromatogr B Biomed Sci Appl. 1997; 695(2): 227-236. https://doi.org/10.1016/S0378-4347(97)00190-4