The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Review of Clinical Researches for Herbal Medicine Treatment on Cerebral Palsy

뇌성마비의 한약치료에 대한 임상연구 동향 -중의학 논문을 중심으로-

  • Lee, Boram (Department of Korean Pediatrics, Graduate School, Kyung Hee University) ;
  • Shin, Hye Jin (Department of Korean Pediatrics, Graduate School, Kyung Hee University) ;
  • Lee, Jihong (Department of Korean Pediatrics, Graduate School, Kyung Hee University) ;
  • Chang, Gyu Tae (Department of Korean Pediatrics, Graduate School, Kyung Hee University)
  • 이보람 (경희대학교 대학원 소아과학교실) ;
  • 신혜진 (경희대학교 대학원 소아과학교실) ;
  • 이지홍 (경희대학교 대학원 소아과학교실) ;
  • 장규태 (경희대학교 대학원 소아과학교실)
  • Received : 2017.07.17
  • Accepted : 2017.08.11
  • Published : 2017.08.31
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Abstract

Objectives The purpose of this study is to provide clinical evidence of herbal medicine treatment for cerebral palsy by reviewing randomized controlled trials conducted in China. Methods We searched literatures dated up to 17 May, 2017 in China National Knowledge Infrastructure (CNKI), and evaluated methodological quality of those studies using 'Risk of Bias' tool. Results Sixteen studies were selected for analysis. These studies indicated that the total effective rate, motor function, self-care, muscle spasticity were significantly improved in the herbal medicine treatment group, as compared to the control group. The most-commonly-used herbs were Poria (茯?), Astragali Radix (黃?), Glycyrrhizae Radix (甘草), and Atractylodis Rhizoma Alba (白朮). There were no serious adverse events found that were associated with herbal medicine treatment. The methodological quality of included studies was generally unclear or low. Conclusions This study shows that the herbal medicine treatment can be effective and safe in treating cerebral palsy. Further well-designed clinical trials with high methodological quality and appropriate assessment tools need to be performed to solidify these findings.

Keywords

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