Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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A pediatric case of relapsed pulmonary alveolar proteinosis despite successful whole lung lavage

  • Jin, Seung Young (Department of Pediatrics, Seoul National University Hospital) ;
  • Yun, Hye Ri (Department of Pediatrics, Seoul National University Hospital) ;
  • Choi, Yun Jung (Department of Pediatrics, Seoul National University Hospital) ;
  • Park, Jun Dong (Department of Pediatrics, Seoul National University Hospital) ;
  • Kim, Jin Tae (Department of Anesthesiology and Pain Medicine, Seoul National University Hospital) ;
  • Kang, Chang Hyun (Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital) ;
  • Park, Young Sik (Department of Internal Medicine and Lung Institute, Seoul National University Hospital) ;
  • Choi, Young Hun (Department of Radiology, Seoul National University Hospital) ;
  • Kim, Woo Sun (Department of Radiology, Seoul National University Hospital) ;
  • Suh, Dong In (Department of Pediatrics, Seoul National University Hospital)
  • Received : 2017.02.20
  • Accepted : 2017.05.17
  • Published : 2017.07.15
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Abstract

Pulmonary alveolar proteinosis (PAP) is a rare disease in children characterized by intra-alveolar accumulation of surfactant proteins, which severely reduces gaseous exchange. Whole lung lavage (WLL) is the preferred technique for the treatment of severe PAP. Herein, we present a pediatric case of PAP treated with WLL. An 11-year-old boy was admitted with the chief complaint of a dry cough lasting 6 months. He developed symptoms of dyspnea on exertion and had difficulty in climbing stairs. He was ultimately diagnosed with PAP through video-assisted thoracoscopic lung biopsy. As first-line of treatment for PAP, he underwent therapeutic WLL for each of his lungs on separate days. After a brief recovery, his symptoms gradually worsened; therefore, he underwent a second WLL. This is the first pediatric case of PAP relapse despite successful WLL in Korea.

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References

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