DOI QR코드

DOI QR Code

Development of Mobile-application based Cognitive Training Program for Cancer Survivors with Cognitive Complaints

암 환자를 위한 앱 기반의 인지건강훈련 프로그램의 개발

  • Oh, Pok Ja (Department of Nursing, Sahmyook University) ;
  • Youn, Jung-Hae (Department of Medicine, Clinical & Counselling Psychology, CHA University) ;
  • Kim, Ji Hyun (Department of Nursing, Sahmyook University)
  • 오복자 (삼육대학교 간호학과) ;
  • 윤정혜 (차의과학대학교 의학대학원 임상상담심리) ;
  • 김지현 (삼육대학교 간호학과)
  • Received : 2017.03.31
  • Accepted : 2017.06.23
  • Published : 2017.04.30

Abstract

Purpose: The purpose of this study was to design a mobile-application of a cognitive training program for people who have chemo-related cognitive complaints. Methods: The program was developed based on the network-based instructional system design proposed by Jung. The program consisted of several tasks centered on four cognitive domains: learning, memory, working memory, and attention. For memory learning, a target-image and all its elements (color, position, and number) were presented on the screen that had to be recognized among a number of distractor-figures. In working memory training, the previous learned target-figure according to the level of difficulty had to be remembered among many different figures. In attention training named "Find the same figure," two identical symbols in a grid-pattern filled with different images were presented on the screen, and these had to be simultaneously touched. In attention training named "Find the different figure," a different symbol in a grid pattern filled with same figures had to be selected. This program was developed to train for a minimum of 20 min/day, four days/week for six weeks. Results: This cognitive training revealed statistically significant improvement in subjective cognitive impairments (t=3.88, p=.006) at six weeks in eight cancer survivors. Conclusion: This cognitive training program is expected to offer individualized training opportunities for improving cognitive function and further research is needed to test the effect in various settings.

Keywords

Acknowledgement

Supported by : 한국연구재단

References

  1. Wefel JS, Kesler SR, Noll KR, Schagen SB. Clinical characteristics, pathophysiology, and management of noncentral nervous system cancer-related cognitive impairment in adults. CA: A Cancer Journal for Clinicians. 2015;65(2):123-38. https://doi.org/10.3322/caac.21258
  2. Kanaskie ML. Chemotherapy-related cognitive change: a principle-based concept analysis. Oncology Nursing Forum. 2012; 39(3):E241-8. https://doi.org/10.1188/12.ONF.E241-E248
  3. Park JH, Bae SH. Jung YS, Jung YM. Prevalence and characteristics of chemotherapy-related cognitive impairment in patients with breast cancer. Journal of Korean Academy of Nursing. 2015;45(1):118-28. https://doi.org/10.4040/jkan.2015.45.1.118
  4. Schagen SB, Muller MJ, Boogerd W, Mellenbergh GJ, van Dam FS. Change in cognitive function after chemotherapy: a prospective longitudinal study in breast cancer patients. Journal of National Cancer Institute. 2006;98(23):1742-5. https://doi.org/10.1093/jnci/djj470
  5. Nelson CJ, Nandy N, Roth AJ. Chemotherapy and cognitive deficits: mechanisms, findings, and potential interventions. Palliative & Supportive Care. 2007;5(3):273-80. https://doi.org/10.1017/S1478951507000442
  6. Milbury K, Chaoul A, Biegler K, Wangyal T, Spelman A, Meyers CA, et al. Tibetan sound meditation for cognitive dysfunction: results of a randomized controlled pilot trial. Psycho-Oncology. 2013;22(10):2354-63. https://doi.org/10.1002/pon.3296
  7. Coyle H, Traynor V, Solowij N. Computerized and virtual reality cognitive training for individuals at high risk of cognitive decline: systematic review of the literature. The American Journal of Geriatric Psychiatry. 2015;23(4):335-59. https://doi.org/10.1016/j.jagp.2014.04.009
  8. Martin M, Clare L, Altgassen AM, Cameron MH, Zehnder F. Cognition-based interventions for healthy older people and people with mild cognitive impairment. Cochrane Database of Systematic Reviews. 2011;1:CD006220. https://doi.org/10.1002/14651858.CD006220.pub2
  9. Gates N, Valenzuela M. Cognitive exercise and its role in cognitive function in older adults. Current Psychiatry Reports. 2010;12(1):20-7. https://doi.org/10.1007/s11920-009-0085-y
  10. Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science. 2000;288(5472):1765-8. https://doi.org/10.1126/science.288.5472.1765
  11. Kim DH, Cho YN, Kwon HC. The effect of Rehacom on cognitive function and activities of daily living for traumatic brain injury. Journal of Special Education & Rehabilitation Science. 2013;52(1):197-216.
  12. Kim SY, Rhee KM. The effect of computer-based cognitive rehabilitation program on visual perception and ADL in children with intellectual disability. Journal of Rehabilitation Welfare Engineering & Assistive Technology. 2015;9(2):105-13.
  13. Shim JM, Kim HH, Lee YS. Effects of computerized neurocognitive function program induced memory and attention for patients with stroke. The Journal of Korean Society of Physical Therapy. 2007;19(4):25-32.
  14. Kim HJ, Yang YS, Choi KH, Kim TY. The effect of computerbased cognitive training program on cognition. Dementia and Neurocognitive Disorders. 2013;12(4):87-93. https://doi.org/10.12779/dnd.2013.12.4.87
  15. Oh PJ, Kim JH. The effects of nonpharmacologic interventions on cognitive function in patients with cancer: a meta-analysis. Oncology Nursing Forum. 2016;43(5):E205-17. https://doi.org/10.1188/16.ONF.E205-E217
  16. Kwon JS, Kim YG, Kim JY, Yuk JS, Cho HJ, Hong SP. Cognitive rehabilitation. Seoul: Pacific Books; 2008. p. 282.
  17. Jung IS. Network-based instructional system design. In: Na IJ, editor. Understanding of distance education. Seoul: Kyoyookbook; 1999. p. 77-99.
  18. Oh PJ, Kim IO, Shin SR, Jung HK. Development of web-based multimedia content for a physical examination and health assessment course. Journal of Korean Academy of Nursing. 2004; 34(6):994-1003. https://doi.org/10.4040/jkan.2004.34.6.994
  19. Wagner LI, Butt Z, Sweet JJ, Cella D. Measuring patient selfreported cognitive function: development of the functional assessment of cancer therapy-cognitive function instrument. The Journal of Supportive Oncology. 2009;7(6):W32-9.
  20. Park JH, Bae SH, Jung YS, Jung YM. The psychometric properties of the Korean version of the functional assessment of cancer therapy-cognitive (FACT-Cog) in Korean patients with breast cancer. Supportive Care in Cancer. 2015;23(9):2695-703. https://doi.org/10.1007/s00520-015-2632-x
  21. Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society. 2005;53(4):695-9. https://doi.org/10.1111/j.1532-5415.2005.53221.x
  22. Lee JY, Lee DW, Cho SJ, Na DL, Jeon HJ, Kim SK, et al. Brief screening for mild cognitive impairment in elderly outpatient clinic: validation of the Korean version of the montreal cognitive assessment. Journal of Geriatric Psychiatry and Neurology. 2008;21(2):104-10. https://doi.org/10.1177/0891988708316855
  23. Kwon JS, Kim YG, Kim JY, Yuk JS, Cho HJ, Hong SP. Cognitive rehabilitation. Seoul: Pacific Books; 2008. p. 199.
  24. Oh PJ, Lee JR. Effect of cancer symptoms and fatigue on chemotherapy-related cognitive impairment and depression in people with gastrointestinal cancer. Journal of Korean Academy of Nursing. 2016;46(3):420-30. https://doi.org/10.4040/jkan.2016.46.3.420
  25. Fougnie D. The relationship between attention and working memory. In: Noah B, Johansen, editors. New research on shortterm memory. New York: Nova Science Publishers; 2008. p.1-45.
  26. Kang MA, Baek YM. The neurocognitive function between the patients who had subjective memory impairment and mild cognitive impairment. Journal of the Korean Geriatrics Society. 2014;18(1):7-15. https://dx.doi.org/10.4235/jkgs.2014.18.1.7
  27. Damholdt MF, Mehlsen M, O'Toole MS, Andreasen RK, Pedersen AD, Zachariae R. Web-based cognitive training for breast cancer survivors with cognitive complaints-a randomized controlled trial. Psycho-Oncology. 2016;25(11):1293-300. https://doi.org/10.1002/pon.4058
  28. Kesler S, Hadi Hosseini SM, Heckler C, Janelsins M, Palesh O, Mustian K, et al. Cognitive training for improving executive function in chemotherapy-treated breast cancer survivors. Clinical Breast Cancer. 2013;13(4);299-306. https://doi.org/10.1016/j.clbc.2013.02.004
  29. Lampit A, Halllock H, Valenzuela M. Computerized cognitive training in cognitively healthy older adults: a systematic review and meta-analysis of effect modifiers. PLOS Medicine. 2014;11(11):e1001756. https://doi.org/10.1371/journal.pmed.1001756