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The Effect of Traditional Korean Medicine Treatment on CREST Syndrome: A Case Report

  • Joung, Jin-yong (Dept. of Internal Medicine, Dae-Jeon Oriental Hospital of Dae-Jeon University) ;
  • Seo, Hyun-sik (Dept. of Internal Medicine, Dae-Jeon Oriental Hospital of Dae-Jeon University) ;
  • Son, Chang-gue (Dept. of Internal Medicine, Dae-Jeon Oriental Hospital of Dae-Jeon University) ;
  • Lee, Nam-hun (Dept. of Internal Medicine, Dae-Jeon Oriental Hospital of Dae-Jeon University) ;
  • Cho, Jung-hyo (Dept. of Internal Medicine, Dae-Jeon Oriental Hospital of Dae-Jeon University)
  • Received : 2017.03.10
  • Accepted : 2017.05.25
  • Published : 2017.05.30

Abstract

CREST syndrome is a form of limited cutaneous scleroderma that occurs only in certain parts of the body, such as the skin of the hands and face. CREST refers to the five main features of the syndrome: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. Currently, there is no standard treatment for CREST syndrome, and there have been no studies of the use of traditional Korean medicine (TKM) for this disease. This study describes the effects of Keumsuyukun-jeon on CREST syndrome. The patient in this case had typical clinical symptoms of CREST syndrome. These symptoms improved within a relatively short period of receiving the TKM treatment. The results of Anti-centromere antibody (AI) and high sensitivity C-reactive protein (mg/L) also improved.

Keywords

References

  1. Allanore Y, Simms R, Distler O, Trojanowska M, Pope J, Denton CP, et al. Systemic sclerosis. Nat Rev Dis Primer 2015;23(1):15002.
  2. Winterbauer RH. Multiple telangiectasia, Raynaud's phenomenon, Sclerodactyly, and Subcutanious Cacinosis: A Syndrome Mimicking Hereditary Hemorrhagic Telangiectasia. Bull Johns Hopkins Hosp 1964;114:361-83.
  3. Steen VD, Powell DL, Medsger TA Jr. Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis. Arthritis Rheum 1988;31(2):196-203. https://doi.org/10.1002/art.1780310207
  4. Mayes MD, Lacey JV Jr, Beebe-Dimmer J, Gillespie BW, Cooper B, Laing TJ, et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 2003;48(8):2246-55. https://doi.org/10.1002/art.11073
  5. Huskisson EC. Measurement of pain. Lancet Lond Engl 1974;2(7889):1127-31.
  6. Velayos EE, Masi AT, Stevens MB, Shulman LE. The 'CREST' syndrome. Comparison with systemic sclerosis (scleroderma). Arch Intern Med 1979;139(11):1240-4. https://doi.org/10.1001/archinte.1979.03630480030012
  7. van Paassen P, Damoiseaux J, Tervaert JW. Laboratory assessment in musculoskeletal disorders. Best Pract. Res. Clin Rheumatol 2003;17(3):475-94. https://doi.org/10.1016/S1521-6942(03)00029-9
  8. Aeschlimann A, Meyer O, Bourgeois P, Haim T, Belmatoug N, Palazzo E, et al. Anti-Scl-70 antibodies detected by immunoblotting in progressive systemic sclerosis: specificity and clinical correlations. Ann. Rheum Dis 1989;48(12):992-7. https://doi.org/10.1136/ard.48.12.992
  9. Muangchan C, Harding S, Khimdas S, Bonner A, Baron M, Pope J. Association of C-reactive protein with high disease activity in systemic sclerosis: results from the Canadian Scleroderma Research Group. Arthritis Care Res 2012;64(9):1405-14. https://doi.org/10.1002/acr.21716
  10. Buchanan RR, Riglar AG. The titre of anticentromere antibodies: its relationship to Raynaud's phenomenon and vascular occlusion. Br J Rheumatol 1989;28(3):221-6. https://doi.org/10.1093/rheumatology/28.3.221
  11. Shim YS, Kim GB, Han JH, Kim SH, Kim EG, Kim SU, et al. A Case Report of Korean Traditional Medical Therapy on Gastric Dysmotility Involved in Patient with Systemic Sclerosis Sine Scleroderma. J Int Korean Med 2004;25(2):344-51.
  12. Kim MK, Jeong JG, Kim KM, Kim HJ, Kim JH, Kim YI, et al. The Effect of Korean Medical Treatment on Systemic Sclerosis : A Case Report. The Acupuncture 2016;33(3):207-18. https://doi.org/10.13045/acupunct.2016048
  13. KimCS, Choi HY, KimJD. Effects of Kumsooyukkunjeon on Asthma Induced by Ovalbumin in Mice. J Korean Orient Med 2002;23(3):104-18.
  14. Jo JK, An CG, Kim KJ, Kim NK, Park MC. Effects of Kumsooyukkun-jeon extract on the Ovalbumin-Induced Allergic Asthma in Mice. J Korean Med Ophthalmol Otolaryngol Dermatol 2007;20(3):107-17.
  15. Song JJ, Park YC, Kim BT, Kim SH, Keum BT, Keum SH. Effect of Kamkeumsooyukkunjeon on Allergy and Lung Damage. Korean J Orient Physiol & Pathol 2000;14(2):70-9.
  16. Hui KK, Johnston MF, Brodsky M, Tafur J, Kim Ho M. Scleroderma, Stress and CAM Utilization. Evid-Based Complement Altern Med 2009;6(4):503-6. https://doi.org/10.1093/ecam/nem142
  17. Szalai AJ. C-reactive protein (CRP) and autoimmune disease: facts and conjectures. Clin Dev Immunol 2004;11(3-4):221-6. https://doi.org/10.1080/17402520400001751