DOI QR코드

DOI QR Code

Utilization of multivalent vaccine on sows ante partum for the prevention of piglet enteritis

  • Oh, Yeonsu (Department of Veterinary Pathology, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Kim, Myung-Hyee (College of Veterinary Medicine, Konkuk University and Hipra Korea) ;
  • Han, Jeong-Hee (Department of Veterinary Pathology, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • Received : 2017.06.22
  • Accepted : 2017.06.27
  • Published : 2017.06.30

Abstract

Three swine farms which were suffering from slight economic loss due to suckling piglets' diarrhea, were selected to apply commercialized multivalent vaccine for sow use; $SUISENG^{(R)}$ (Hipra, Spain). Farms were pre-diagnosed with clinical symptoms and molecular detection of C. perfringens Type A and C and E. coli pili by PCR. Sows were vaccinated twice 2 ml of the vaccine at 6 and 3 weeks ante partum intramuscularly according to the manufacturer's instruction. All vaccinated sows did not show any adverse reaction or clinical signs; hypersensitivity, fever, granuloma or abscess on the injection site, appetite loss, and so on. Also, no reproductive disorder was appeared in vaccinated sows compared with non-vaccinated control sows. The results suggested that piglets born from vaccinated sows show significantly better performance in regard of the diarrhea index and mean daily weight gain compared with piglets from non-vaccinated sows. Therefore, the commercial vaccine for the prevention of neonatal diarrhea is found to be effective in reducing diarrhea in the first suckling period of piglets after birth.

Keywords

References

  1. Baker AA, Davis E, Reberger T, Rosener D. 2010. Prevalence and diversity of toxigenic Clostridium perfringens and Clostridium difficile among swine herds in the midwest. Appl Environ Microbiol 76: 2961-2967. https://doi.org/10.1128/AEM.02459-09
  2. Chan G, Farzan A, Prescott JF, Friendship R. 2013. How do swine practitioners and veterinary pathologists arrive at a diagnosis of Clostridium perfringens type A enteritis in neonatal piglets? Can Vet J 54: 504-506.
  3. Goede D, Murtaugh MP, Nerem J, Yeske P, Rossow K, Morrison R. 2015. Previous infection of sows with a "mild" strain of porcine epidemic diarrhea virus confers protection against infection with a ''severe'' strain. Vet Microbiol 176: 161-164. https://doi.org/10.1016/j.vetmic.2014.12.019
  4. Hammer JM, Fuhrman M, Walz M. 2008. Serological evaluation of a Clostridium perfringens type A toxoid in a commercial swine herd. J Swine Health Prod 16: 37-40.
  5. Han SJ, Oh Y, Lee CY, Han JH. 2016. Efficacy of dietary supplementation of bacteriophages in treatment of concurrent infections with enterotoxigenic Escherichia coli K88 and K99 in postweaning pigs. J Swine Health Prod 24: 259-263.
  6. Kongsted H, Toft N, Nielsen JP. 2014. Risk factors and epidemiological characteristics of new neonatal porcine diarrhea syndrome in four Danish herds. BMC Vet Res 10: 151. https://doi.org/10.1186/1746-6148-10-151
  7. Marquardt RR, Jin LZ, Kim JW, Fang L, Frohlich AA, Baidoo SK. 1999. Passive protective effect of egg-yolk antibodies against enterotoxigenic Escherichia coli K88+ infection in neonatal and early-weaned piglets. FEMS Immunol Med Microbiol 23: 283-288. https://doi.org/10.1111/j.1574-695X.1999.tb01249.x
  8. Ogawa H, Taira O, Hirai T, Takeuchi H, Nagao A, Ishikawa Y, Tuchiya K, Nunoya T, Ueda S. 2009. Multiplex PCR and multiplex RT-PCR for inclusive detection of major swine DNA and RNA viruses in pigs with multiple infections. J Virol Methods 160: 210-214. https://doi.org/10.1016/j.jviromet.2009.05.010
  9. Oh Y, Seo HW, Han K, Park C, Chae C. 2012. Protective effect of the maternally derived porcine circovirus type 2 (PCV2)-specific cellular immune response in piglets by dam vaccination against PCV2 challenge. J Gen Virol 93: 1556-1562. https://doi.org/10.1099/vir.0.041749-0
  10. Parra GI, Vidales G, Gomez JA, Fernandez FM, Parreno V, Bok K. 2008. Phylogenetic analysis of porcine rotavirus in Argentina: Increasing diversity of G4 strains and evidence of interspecies transmission. Vet Microbiol 126: 243-250. https://doi.org/10.1016/j.vetmic.2007.06.006
  11. Sjolund M, Zoric M, Wallgren P. Financial impact of disease on pig production. Part III. Gastrointestinal disorders. In: Proceedings of 6th European Symposium of Porcine Health Management, Sorrento, Italy, 2014, p. 189.
  12. Uzal FA. 2004. Diagnosis of Clostridium perfringens intestinal infections in sheep and goats. Anaerobe 10: 135-143. https://doi.org/10.1016/j.anaerobe.2003.08.005
  13. Vemulapalli R, Gulani J, Santrich C. 2009. A real-time TaqMan RT-PCR assay with an internal amplification control for rapid detection of transmissible gastroenteritis virus in swine fecal samples. J Virol Methods 162: 231-235. https://doi.org/10.1016/j.jviromet.2009.08.016
  14. Wang X, Ren W, Nie Y, Cheng L, Tan W, Wang C, Wei L, Zhang R, Yan G. 2013. A novel watery diarrhea caused by the co-infection of neonatal piglets with Clostridium perfringens type A and Escherichia coli (K88, 987P). 197: 812-816. https://doi.org/10.1016/j.tvjl.2013.05.023
  15. Westin R, Holmgren N, Hultgren J, Ortman, K, Linder A, Algers, B. 2015. Post-mortem findings and piglet mortality in relation to strategic use of straw at farrowing. Prev Vet Med 119: 141-152. https://doi.org/10.1016/j.prevetmed.2015.02.023
  16. Wise R, Hart T, Cars O, Streulens M, Helmuth R, Huovinen P, Sprenger M. 1998. Antimicrobial resistance: is a major threat to public health. BMJ: British Medical Journal 317: 609-610. https://doi.org/10.1136/bmj.317.7159.609
  17. Zanelloa G, Meurens F, Serreau D, Chevaleyre C, Melo S, Berri M, D’Inca R, Auclaira E, Salmon H. 2012. Effects of dietary yeast strains on immunoglobulin in colostrum and milk of sows. Vet Immunol Immunopathol 152: 20-27.