Quantitative Analysis of Icariside E5 and Vanilloyl Icariside E5 from the Seed of Capsicum annuum. L

고추씨로부터 Icariside E5와 Vanilloyl Icariside E5의 함량분석

  • Youn, Sung Hye (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Yin, Jun (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Ahn, Hye Shin (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Tam, Le Thi (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University) ;
  • Kwon, Suk Hyung (Novarex) ;
  • Min, Bokkee (Novarex) ;
  • Yun, Seong Ho (Novarex) ;
  • Kim, Hwa Yeon (Novarex) ;
  • Lee, Min Won (Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University)
  • Received : 2017.05.18
  • Accepted : 2017.06.12
  • Published : 2017.06.30

Abstract

Capsicum annuum L. (CA) is reported to be the most widely cultivated species of the Capsicum throughout the world. Its fruit and the seeds have been used as spice after drying and grinding. It is reported that the fruit and seeds contain capsaicinoid such as capsaicin and dihydrocapsaicin, carotenoid such as capsanthin and ${\beta}$-carotene with its anti-tumor effect, anti-obesity effect, anti-diabetic action. Present study, we isolated two lignans, icariside $E_5$ and vanilloyl icariside $E_5$ from the seed of CA and validation and content determination were confirmed using High-Performance Liquid Chromatography (HPLC). As a result, the contents of the lignans, icariside $E_5$ and vanilloyl icariside $E_5$ were 0.28%, 0.085%, respectively in the extract.

Keywords

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