Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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A Case of Meningoencephalitis Managed with Imatinib Mesylate in a Maltese Dog; Clinical and Serial Magnetic Resonance Imaging Findings

말티즈 견에서 발생한 뇌수막염에서 이마티닙을 적용한 증례; 임상적 그리고 연속적인 자기공명영상 결과

  • Jung, Dong-In (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • An, Su-Jin (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Hwang, Tae-Sung (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Song, Joong-Hyun (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Cho, Kyu-Woan (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University)
  • 정동인 (경상대학교 수의과대학 동물의학연구소) ;
  • 안수진 (경상대학교 수의과대학 동물의학연구소) ;
  • 황태성 (경상대학교 수의과대학 동물의학연구소) ;
  • 이희천 (경상대학교 수의과대학 동물의학연구소) ;
  • 송중현 (경상대학교 수의과대학 동물의학연구소) ;
  • 조규완 (경상대학교 수의과대학 동물의학연구소)
  • Received : 2016.12.05
  • Accepted : 2017.03.30
  • Published : 2017.04.28
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Abstract

A 5-year-old intact female Maltese dog was referred to us with a history of left side head tilt and ataxia. Based on magnetic resonance imaging (MRI) and cerebrospinal fluid analysis results, the patient was tentatively diagnosed to meningoencephalitis of unknown etiology (MUE). Clinical signs were gradually improved and diminished after imatinib mesylate plus prednisolone therapy. At 90 days after treatment, we performed MRI recheck and brain inflammatory lesions were significantly improved compared with initial MRI results. However, the present patient showed head turn and tetraparesis after anesthesia and euthanized according to client's request. This report describes the clinical findings, serial magnetic resonance imaging characteristics under imatinib mesylate treatment in a MUE case.

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References

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