Abstract
The main function of an infuser is to ensure constant dosage of a drug. Elastomer drug infusers have been used widely owing to their economic advantages. The mechanism of the device is primarily based on the pressure created from the elastic material that contains the drugs. However, as the drug is infused and the internal pressure is reduced, the drug is not linearly infused at all times. This study involves investigating factors to improve the design of the infuser. The first factor is the range of proper deformation, which does not affect a significant amount of stress variation during infusion. The second is concerned with the flow restrictor and the associated design variables are recommended by employing finite element analysis and the factorial experiment technique. The last factor is related to the spring device connected to balloon. The results showed that the drug reservoir can compensate for unexpected pressure gradient drops.