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A Study on the Detection of Abnormal Tissues in Biological Tissue Using Temperature Distribution According to Light Irradiation

광 조사에 따른 온도분포를 이용한 생체조직 내 비정상조직 탐지에 대한 연구

  • Ko, Dong Guk (Dept. of Mechanical Engineering, College of Engineering, Chonbuk Nat'l Univ.) ;
  • Im, Ihk-Tae (Dept. of Mechanical Design Engineering, College of Engineering, Chonbuk Nat'l Univ.)
  • 고동국 (전북대학교 공과대학 기계공학과) ;
  • 임익태 (전북대학교 공과대학 기계설계공학부)
  • Received : 2016.07.28
  • Accepted : 2017.02.27
  • Published : 2017.05.01

Abstract

In this study, the characteristics of the temperature generated by light irradiation, on the surface of a biological tissue with an abnormal tissue part (paraffin) and at the surroundings of the abnormal tissue were studied by numerical and experimental methods. The temperature in the tissue was solved using the computational heat transfer and was compared with the temperature measured with thermocouples. The effects of the light wavelength and the irradiation time on the temperature distribution were analyzed. As a result, the temperature distribution from the irradiation of light in the biological tissue was different when there was an abnormal tissue part. The temperature in the biological tissue with the abnormal tissue part was higher than in a normal tissue.

본 연구에서는 비정상조직(파라핀)을 가진 생체조직에 광을 조사하고 그에 따른 조직의 표면온도와 비정상조직 주위에서의 온도분포를 실험과 해석적 방법을 통해 분석하였다. 파라핀을 이용하여 비정상 조직을 모사한 후 조사하는 광의 파장과 시간을 변화시키면서 조직 주위에서의 온도를 K형 열전대를 사용하여 측정하였다. 또한 전산열전달 기법을 이용하여 해석적으로 조직에 대한 온도분포를 예측하였다. 정상조직과 비정상조직의 주위에서의 온도는 차이가 있었으며, 비정상조직이 있는 경우 표면과 조직 주위의 온도가 높게 나타났다.

Keywords

References

  1. Ito, Y., Kennan, R. P., Watanabe, E. and Koizumi, H., 2000, "Assessment of Heating Effects in Skin During Continuous Wave Near Infrared Spectroscopy," Journal of Biomedical Optics, Vol. 5, No. 4, pp. 383-390. https://doi.org/10.1117/1.1287730
  2. Amber, L., Shada, Lynn T., Dengel, Gina, R., Petroni, Mark E, Smolkin, MS., Scott Acton, and Craig L, Slingluff Jr, 2013, "Infrared Thermography of Cutaneous Melanoma Metastases," Journal of Surgical Research, Vol. 82, pp. 9-14.
  3. Santa Cruz, G.A., Bertotti, J., Marin, J., Gonzalez, S.J., Gossio, S., Alvarez, D., Roth, B.M.C., Menendez, P., Pereira, M.D., Albero, M., Cubau, L., Orellano, P. and Liberman, S.J., 2009, "Dynamic Infrared Imaging of Cutaneous Melanoma and Normal Skin in Patients Treated with BNCT," Journal of applied radiation and isotopes, Vol. 67, pp. 554-558.
  4. Shih, T. C., Yuan, P., Lin, W. L. and Kou, H. S., 2007, "Analytical Analysis of the Pennes Bioheat Transfer Equation with Sinusoidal Heat Flux Condition on Skin Surface," Medical Engineering & Physics, Vol. 29, pp. 946-953. https://doi.org/10.1016/j.medengphy.2006.10.008
  5. Choi, W. L., Moon, S. D., Yoon, S. B. and Im, I. T., 2011, "Analysis of the Bioheat Equation Considering Tissue Layers with Sinusoidal Temperature Oscillation on the Skin," Trans. Korean Soc. Mech. Eng. B, Vol. 35, No. 8, pp. 757-762. https://doi.org/10.3795/KSME-B.2011.35.8.757
  6. Im, I. T., Yoon, S. B. and Kim, K. W., 2015, "Numerical Study on the Temperature Profiles and Degree of Burns in Human Skin Tissue during Thermal Therapy," Numerical Heat Transfer, Vol. 67, No. 9, pp. 921-933. https://doi.org/10.1080/10407782.2014.955338
  7. Ko, D. G., Bae, S. W. and Im, I. T., 2015, "A Study on the Boundary Condition for Analysis of Bio-heat Equation According to Light Irradiation," Trans. Korean Soc. Mech. Eng. B, Vol. 39, No. 11, pp. 853-859. https://doi.org/10.3795/KSME-B.2015.39.11.853
  8. Sid M. Becker and Andrey V. Kuznetsov., 2015, Heat Transfer and Fluid Flow in Biological Processes, Academic Press, London.
  9. Lee, J. H and Kim, T. H., 2001, "A Experimntal Study on the Ultrasonic Influence for Melting the Paraffin and the Ice," The Society of Air-Conditioning And Refrigerating Engineers of Korea, Vol. 13, No. 11, pp. 1106-1113.
  10. Jin, S. Y., Kim, M. H., Kim, H. J., Shim, D. T., Kim, S. W. and Kim, C. D., 2003, "Contemporary Augmentation Rhinoplasty with Autogenous Cartilage Grafts After Removal of Nasal Paraffinoma," Korean Society of Otorhinolaryngology-Head and Neck Surgery, Vol. 46. No. 9, pp. 752-757.
  11. Incropera, F. P. and Dewitt, D. P., 2008, Fundamentals of Heat and Mass Transfer, Fourth Edition, Willey, Toronto.