Journal of Korean Neurosurgical Society

  • 제60권3호
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  • Pages.371-374
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  • 2017
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  • 2005-3711(pISSN)
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  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
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Giant Ganglioneuroma of Thoracic Spine : A Case Report and Review of Literature

  • Huang, Yong (Department of Orthopedics, The First Hospital of Jilin University) ;
  • Liu, Lidi (Department of Orthopedics, The First Hospital of Jilin University) ;
  • Li, Qiao (Department of Orthopedics, The First Hospital of Jilin University) ;
  • Zhang, Shaokun (Department of Orthopedics, The First Hospital of Jilin University)
  • 투고 : 2015.08.04
  • 심사 : 2016.02.19
  • 발행 : 2017.05.01
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초록

Ganglioneuroma (GN) is a rare benign tumor of neural crest origin usually found in the abdomen, but may occasionally present at uncommon sites including the cervical, lumbar, or sacral spine. However, GNs of thoracic spine are extremely rare. In this report, we describe a 12-year-old girl with giant GN in the thoracic spine, who underwent successful resection (T1-4 level) of the tumor. Histopathological examination confirmed the diagnosis. GN should be considered in the differential diagnosis of any paraspinal mass. A high index of suspicion and correlation of clinico-radiological findings is necessary in differentiating a large benign tumor from a malignant growth. Complete surgical excision is the treatment of choice; however tumor size and location need to be considered for the surgical approach (one-step or multiple surgeries). Close follow-up after surgery is mandatory.

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참고문헌

  1. Hioki A, Miyamoto K, Hirose Y, Kito Y, Fushimi K, Shimizu K : Cervical symmetric dumbbell ganglioneuromas causing severe paresis. Asian Spine J 8 : 74-78, 2014 https://doi.org/10.4184/asj.2014.8.1.74
  2. Kara T, Oztunali C : Radiologic findings of thoracic scoliosis due to giant ganglioneuroma. Clin Imaging 37 : 767-768, 2013 https://doi.org/10.1016/j.clinimag.2012.11.003
  3. Kyoshima K, Sakai K, Kanaji M, Oikawa S, Kobayashi S, Sato A, et al. : Symmetric dumbbell ganglioneuromas of bilateral C2 and C3 roots with intradural extension associated with von Recklinghausen's disease: case report. Surg Neurol 61 : 468-473; discussion 473, 2004 https://doi.org/10.1016/S0090-3019(03)00393-8
  4. Pang BC, Tchoyoson Lim CC, Tan KK : Giant spinal ganglioneuroma. J Clin Neurosci 12 : 967-972, 2005 https://doi.org/10.1016/j.jocn.2004.10.017
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  6. Tsai FJ, Kuo KL, Tzou RD, Cheng YH, Hwang SL, Lieu AS : A huge extradural ganglioneuroma of the lumbar spine. Formosan J Surg 47 : 160-165, 2014 https://doi.org/10.1016/j.fjs.2014.04.001
  7. Ugarriza LF, Cabezudo JM, Ramirez JM, Lorenzana LM, Porras LF : Bilateral and symmetric C1-C2 dumbbell ganglioneuromas producing severe spinal cord compression. Surg Neurol 55 : 228-231, 2001 https://doi.org/10.1016/S0090-3019(01)00363-9
  8. Vardas K, Manganas D, Papadimitriou G, Vougas V, Bakalis A, Chantziara M, et al. : Presacral ganglioneuroma: diagnostic considerations and therapeutic strategy. Case Rep Oncol 6 : 561-568, 2013 https://doi.org/10.1159/000356707

피인용 문헌

  1. Neuro-muscular rehabilitation approach with favorable results in a case of a tetraplegia after a cervical ganglioneuroma - case presentation vol.11, pp.4, 2017, https://doi.org/10.12680/balneo.2020.395
  2. Mediastinal ganglioneuroma with osseous invasion simulating malignant transformation of osteochondroma on CT imaging ☆ vol.16, pp.1, 2021, https://doi.org/10.1016/j.radcr.2020.10.010