References
- Leung DYM, Bieber T. Atopic dermatitis. Lancet 2003;361:151-60. https://doi.org/10.1016/S0140-6736(03)12193-9
- Novak N. New insights into the mechanism and management of allergic diseases: atopic dermatitis. Allergy 2009;64:265-75. https://doi.org/10.1111/j.1398-9995.2008.01922.x
- Sebastiani S, Albanesi C, De PO, Puddu P, Cavani A, Girolomoni G. The role of chemokines in allergic contact dermatitis. Arch Dermatol Res 2002;293:552-9. https://doi.org/10.1007/s00403-001-0276-9
- Grone A. Keratinocytes and cytokines. Vet Immunol Immunopathol 2002;88:1-12. https://doi.org/10.1016/S0165-2427(02)00136-8
- Uchi H, Terao H, Koga T, Furue M. Cytokines and chemokines in the epidermis. J Dermatol Sci 2000;24(Suppl. 1):S29-38. https://doi.org/10.1016/S0923-1811(00)00138-9
- Barker JN, Jones ML, Mitra RS, Crockett-Torabe E, Fantone JC, Kunkel SL, Warren JS, Dixit VM, Nickoloff BJ. Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes. Am J Pathol 1991;139:869-76.
- Horikawa T, Nakayama T, Hikita I, Yamada H, Fujisawa R, Bito T, Harada S, Fukunaga A, Chantry D, Gray PW, et al. IFN-gamma-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis. Int Immunol 2002;14:767-73. https://doi.org/10.1093/intimm/dxf044
- Galli SJ, Kalesnikoff J, Grimbaldeston MA, Piliponsky AM, Williams CM, Tsai M. Mast cells as ”tunable“ effector and immunoregulatory cells: recent advances. Annu Rev Immunol 2005;23:749-86. https://doi.org/10.1146/annurev.immunol.21.120601.141025
- Kawakami T, Ando T, Kimura M, Wilson BS, Kawakami Y. Mast cells in atopic dermatitis. Curr Opin Immunol 2009;21:666-78. https://doi.org/10.1016/j.coi.2009.09.006
- Theoharides TC, Alysandratos KD, Angelidou A, Delivanis DA, Sismanopoulos N, Zhang B, Asadi S, Vasiadi M, Weng Z, Miniati A, et al. Mast cells and inflammation. Biochim Biophys Acta 2012;1822:21-33. https://doi.org/10.1016/j.bbadis.2010.12.014
- Galli SJ, Tsai M. Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity. Eur J Immunol 2010;40:1843-51. https://doi.org/10.1002/eji.201040559
- Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002;298:1911-2. https://doi.org/10.1126/science.1072682
- Hommes DW, Peppelenbosch MP, van Deventer SJ. Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets. Gut 2003;52:144-51. https://doi.org/10.1136/gut.52.1.144
- May MJ, Ghosh S. Signal transduction through NF-kappa B. Immunol Today 1998;19:80-8. https://doi.org/10.1016/S0167-5699(97)01197-3
- Arthur JS, Ley SC. Mitogen-activated protein kinases in innate immunity. Nat Rev Immunol 2013;13:679-92. https://doi.org/10.1038/nri3495
- Finco TS, Baldwin AS. Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis. Immunity 1995;3:263-72. https://doi.org/10.1016/1074-7613(95)90112-4
- Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-71. https://doi.org/10.1056/NEJM199704103361506
- Barnes PJ. Pathophysiology of allergic inflammation. Immunol Rev 2011;242:31-50. https://doi.org/10.1111/j.1600-065X.2011.01020.x
- Choi J, Kim TH, Choi TY, Lee MS. Ginseng for health care: a systematic review of randomized controlled trials in Korean literature. PLoS ONE 2013;8:e59978. https://doi.org/10.1371/journal.pone.0059978
- Heo JH, Lee ST, Oh MJ, Park HJ, Shim JY, Chu K, Kim M. Improvement of cognitive deficit in Alzheimer's disease patients by long term treatment with Korean Red Ginseng. J Ginseng Res 2011;35:457-61. https://doi.org/10.5142/jgr.2011.35.4.457
- Park JB, Kwon SK, Nagar H, Jung SB, Jeon BH, Kim CS, Oh JH, Song HJ, Kim CS. Rg3-enriched Korean Red Ginseng improves vascular function in spontaneously hypertensive rats. J Ginseng Res 2014;38:244-50. https://doi.org/10.1016/j.jgr.2014.05.011
- Jung JH, Kang IG, Kim DY, Hwang YJ, Kim ST. The effect of Korean Red Ginseng on allergic inflammation in a murine model of allergic rhinitis. J Ginseng Res 2013;37:167-75. https://doi.org/10.5142/jgr.2013.37.167
- Lee EJ, Song MJ, Kwon HS, Ji GE, Sung MK. Oral administration of fermented red ginseng suppressed ovalbumin-induced allergic responses in female BALB/c mice. Phytomedicine 2012;19:896-903. https://doi.org/10.1016/j.phymed.2012.04.008
- Im EJ, Yayeh T, Park SJ, Kim SH, Goo YK, Hong SB, Son YM, Kim SD, Rhee MH. Antiatherosclerotic effect of Korean Red Ginseng extract involves regulator of g-protein signaling 5. Evid Based Complement Alternat Med 2014;2014:985174.
- Han JY, Ahn SY, Oh EH, Nam SY, Hong JT, Oh KW, Lee MK. Red ginseng extract attenuates kainate-induced excitotoxicity by antioxidative effects. Evid Based Complement Alternat Med 2012;2012:479016.
- Jhun J, Lee J, Byun JK, Kim EK, Woo JW, Lee JH, Kwok SK, Ju JH, Park KS, Kim HY, et al. Red ginseng extract ameliorates autoimmune arthritis via regulation of STAT3 pathway, Th17/Treg balance, and osteoclastogenesis in mice and human. Mediators Inflamm 2014;2014:351856.
- Kim SJ, Kee JY, Choi IY, Kim MC, Kim DS, Jeon YD, Kim SG, Kim BS, Jung HJ, Kim HM, et al. Insamhodo-tang, a traditional Korean medicine, regulates mast cell-mediated allergic inflammation in vivo and in vitro. J Ethnopharmacol 2011;134:339-47. https://doi.org/10.1016/j.jep.2010.12.023
- Albanesi C. Keratinocytes in allergic skin diseases. Curr Opin Allergy Clin Immunol 2010;10:452-6. https://doi.org/10.1097/ACI.0b013e32833e08ae
- Ko HM, Joo SH, Kim P, Park JH, Kim HJ, Bahn GH, Kim HY, Lee J, Han SH, Shin CY, et al. Effects of Korean Red Ginseng extract on tissue plasminogen activator and plasminogen activator inhibitor-1 expression in cultured rat primary astrocytes. J Ginseng Res 2013;37:401-12. https://doi.org/10.5142/jgr.2013.37.401
- Im GJ, Chang JW, Choi J, Chae SW, Ko EJ, Jung HH. Protective effect of Korean Red Ginseng extract on cisplatin ototoxicity in HEI-OC1 auditory cells. Phytother Res 2010;24:614-21.
- Mitev V, Miteva L. Signal transduction in keratinocytes. Exp Dermatol 1999;8:96-108. https://doi.org/10.1111/j.1600-0625.1999.tb00355.x
- Duan W, Wong WS. Targeting mitogen-activated protein kinases for asthma. Curr Drug Targets 2006;7:691-8. https://doi.org/10.2174/138945006777435353
- Lee JH, Cho SH. Korean Red Ginseng extract ameliorates skin lesions in NC/Nga mice: an atopic dermatitis model. J Ethnopharmacol 2011;133:810-7. https://doi.org/10.1016/j.jep.2010.11.020
- Cho E, Cho SH. Effects of Korean Red Ginseng extract on the prevention of atopic dermatitis and its mechanism on early lesions in a murine model. J Ethnopharmacol 2013;145:294-302. https://doi.org/10.1016/j.jep.2012.11.006
- Sohn EH, Jang SA, Lee CH, Jang KH, Kang SC, Park HJ, Pyo S. Effects of Korean Red Ginseng extract for the treatment of atopic dermatitis-like skin lesions in mice. J Ginseng Res 2011;35:479-86. https://doi.org/10.5142/jgr.2011.35.4.479
- Pease JE, Williams TJ. Chemokines and their receptors in allergic disease. J Allergy Clin Immunol 2006;118:305-18. https://doi.org/10.1016/j.jaci.2006.06.010
- Saeki H, Tamaki K. Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseases. J Dermatol Sci 2006;43:75-84. https://doi.org/10.1016/j.jdermsci.2006.06.002
- Kimata H, Lindley I. Detection of plasma interleukin-8 in atopic dermatitis. Arch Dis Child 1994;70:119-22. https://doi.org/10.1136/adc.70.2.119
- Jahnz-Rozyk K, Targowski T, Paluchowska E, Owczarek W, Kucharczyk A. Serum thymus and activation-regulated chemokine, macrophage-derived chemokine and eotaxin as markers of severity of atopic dermatitis. Allergy 2005;60:685-8. https://doi.org/10.1111/j.1398-9995.2005.00774.x
- Shimada Y, Takehara K, Sato S. Both Th2 and Th1 chemokines (TARC/CCL17, MDC/CCL22, and Mig/CXCL9) are elevated in sera from patients with atopic dermatitis. J Dermatol Sci 2004;34:201-8. https://doi.org/10.1016/j.jdermsci.2004.01.001
- Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988;106:761-71. https://doi.org/10.1083/jcb.106.3.761
- Pastore S, Lulli D, Potapovich AI, Fidanza P, Kostyuk VA, Dellambra E, De Luca C, Maurelli R, Korkina LG. Differential modulation of stress-inflammation responses by plant polyphenols in cultured Normal human keratinocytes and immortalized HaCaT cells. J Dermatol Sci 2011;63:104-14.
- Hamann K, Grabbe J, Welker P, Haas N, Algermissen B, Czarnetzki BM. Phenotypic evaluation of cultured human mast and basophilic cells and of Normal human skin mast cells. Arch Dermatol Res 1994;286:380-5. https://doi.org/10.1007/BF00371797
- Navi D, Saegusa J, Liu FT. Mast cells and immunological skin diseases. Clin Rev Allergy Immunol 2007;33:144-55. https://doi.org/10.1007/s12016-007-0029-4
- Hong CE, Lyu SY. Anti-inflammatory and anti-oxidative effects of Korean Red Ginseng extract in human keratinocytes. Immune Netw 2011;11:42-9. https://doi.org/10.4110/in.2011.11.1.42
- Qi XF, Kim DH, Yoon YS, Li JH, Song SB, Jin D, Huang XZ, Teng YC, Lee KJ. The adenylyl cyclase-cAMP system suppresses TARC/CCL17 and MDC/CCL22 production through p38 MAPK and NF-kappaB in HaCaT keratinocytes. Mol Immunol 2009;46:1925-34. https://doi.org/10.1016/j.molimm.2009.03.018
- Yano C, Saeki H, Komine M, Kagami S, Tsunemi Y, Ohtsuki M, Nakagawa H. Mechanism of macrophage-derived chemokine/CCL22 production by HaCaT keratinocytes. Ann Dermatol 2015;27:152-6. https://doi.org/10.5021/ad.2015.27.2.152
Cited by
- Neuroprotective effects of Rg3-enriched Korean Red Ginseng on alcohol-induced apoptosis in PC12 Cells vol.18, pp.12, 2017, https://doi.org/10.5762/kais.2017.18.12.521
- Current Status of Research on Ginseng Cosmetics vol.16, pp.4, 2018, https://doi.org/10.20402/ajbc.2018.0249
- Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin vol.21, pp.None, 2017, https://doi.org/10.1016/j.redox.2018.101080
- Taeumjowi-tang, a Traditional Korean Sasang Remedy, Improves Obesity-Atopic Dermatitis Comorbidity by Regulating Hypoxia-Inducible Factor 1 Alpha vol.10, pp.None, 2017, https://doi.org/10.3389/fphar.2019.01458
- Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells vol.11, pp.3, 2017, https://doi.org/10.3390/nu11030573
- Atopic Dermatitis-Related Inflammation in Macrophages and Keratinocytes: The Inhibitory Effects of Bee Venom vol.36, pp.2, 2019, https://doi.org/10.13045/jar.2019.00038
- Ginsenoside Rh2 Ameliorates Atopic Dermatitis in NC/Nga Mice by Suppressing NF-kappaB-Mediated Thymic Stromal Lymphopoietin Expression and T Helper Type 2 Differentiation vol.20, pp.24, 2017, https://doi.org/10.3390/ijms20246111
- Anti-Inflammatory Effects of Bee Venom on Phthalic Anhydride-Induced Atopic Dermatitis vol.37, pp.1, 2017, https://doi.org/10.13045/jar.2019.00087
- 국내 한의학 학술지에 발표된 항염증 한약재 및 한약처방 연구동향 - 2015년 이후 발표된 실험논문을 중심으로 - vol.36, pp.1, 2017, https://doi.org/10.6116/kjh.2021.36.1.19.
- Effect of Korean Red Ginseng and Rg3 on Asian Sand Dust-Induced MUC5AC, MUC5B, and MUC8 Expression in Bronchial Epithelial Cells vol.26, pp.7, 2017, https://doi.org/10.3390/molecules26072002
- Inhibition of Angiogenic Factor Productions by Quercetin In Vitro and In Vivo vol.8, pp.5, 2017, https://doi.org/10.3390/medicines8050022
- Skullcapflavone II Suppresses TNF-α/IFN-γ-Induced TARC, MDC, and CTSS Production in HaCaT Cells vol.22, pp.12, 2021, https://doi.org/10.3390/ijms22126428
- Effects of Deacetylasperulosidic Acid on Atopic Dermatitis through Modulating Immune Balance and Skin Barrier Function in HaCaT, HMC-1, and EOL-1 Cells vol.26, pp.11, 2021, https://doi.org/10.3390/molecules26113298
- Inhibitory effect of paeoniflorin on IgE-dependent and IgE-independent mast cell degranulation in vitro and vivo vol.12, pp.16, 2017, https://doi.org/10.1039/d1fo01421h
- Alpinia officinarum water extract inhibits the atopic dermatitis-like responses in NC/Nga mice by regulation of inflammatory chemokine production vol.144, pp.None, 2021, https://doi.org/10.1016/j.biopha.2021.112322
- Effect of steam-processing of the Panax ginseng root on its inducible activity on granulocyte-colony stimulating factor secretion in intestinal epithelial cells in vitro vol.287, pp.None, 2017, https://doi.org/10.1016/j.jep.2021.114927