Mass Spectrometry Letters

  • 제8권1호
  • /
  • Pages.18-22
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  • 2017
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  • 2233-4203(pISSN)
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  • 2093-8950(eISSN)
한국질량분석학회 (Korean Society for Mass Spectrometry)
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Comparative Study of Extracting Fragrance Allergens by GC-MS/MS

  • Lee, In Ja (Seoul Water Institute, Seoul Metropolitan Government) ;
  • Ahn, Jae-Chan (Seoul Water Institute, Seoul Metropolitan Government) ;
  • Kim, Bogsoon (Seoul Water Institute, Seoul Metropolitan Government) ;
  • Chung, Deukmo (Seoul Water Institute, Seoul Metropolitan Government)
  • 투고 : 2017.03.06
  • 심사 : 2017.03.20
  • 발행 : 2017.03.30
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초록

Products containing any one or more of 26 fragrance allergens likely to cause contact allergies, are required under the 2008 domestic cosmetic law to be labeled when their concentrations exceed a certain range. This study focuses on the comparison and development of analytical methods based on headspace-solid phase micro extraction (HS-SPME) and liquid-liquid extraction (LLE) methods followed by GC-MS/MS for 24 of the fragrance allergens excepting for two natural materials in water samples. Using the developed HS-SPME method, 15 of the 24 fragrance allergens were analyzed and 9 compounds which have relatively low $logK_{OW}$ values (below about 2.5) were not extracted, and the correlation coefficient ($r^2$) of the calibration curve for quantification showed linearity of 0.9969 or more, and the method detection limits (MDL) and the limits of quantification (LOQ) were $0.078{\sim}0.582{\mu}g/L$ and $0.261{\sim}1.940{\mu}g/L$, respectively. In the case of using the optimized LLE method, all 24 fragrance allergens were analyzed, and the correlation coefficient ($r^2$) of the calibration curve for quantification showed linearity of 0.9957 or more, MDL and LOQ were $0.020{\sim}0.138{\mu}g/L$ and $0.065{\sim}0.440{\mu}g/L$, respectively.

키워드

참고문헌

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피인용 문헌

  1. Determining Collision Cross-Sections of Aromatic Compounds in Crude Oil by Using Aromatic Compound Mixture as Calibration Standard vol.40, pp.2, 2018, https://doi.org/10.1002/bkcs.11653