Natural Product Sciences

  • 제23권1호
  • /
  • Pages.69-74
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  • 2017
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  • 1226-3907(pISSN)
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  • 2288-9027(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
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DOI QR코드

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Anti-microbial and Anti-inflammatory Activity of New 4-methoxy-3-(methoxymethyl) Phenol and (E)-N'-(5-bromo-2-methoxybenzylidene)-4-methoxy Benzohydrazide Isolated from Calotropis gigantean white

  • Manivannan, R. (Department of Chemistry, Government Arts College (Autonomous)) ;
  • Shopna, R. (Department of Chemistry, Government Arts College (Autonomous))
  • 투고 : 2016.11.01
  • 심사 : 2017.01.12
  • 발행 : 2017.03.31
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초록

A new phenol and hydrazide derivatives were obtained for the first time from the C. giganteawhite by silica gel column chromatography. The structure of the isolated compounds was identified by UV, IR NMR and MS. C. gigantea was scientifically reported for several medicinal properties viz. analgesic, antimicrobial and cytotoxic. In this screening work, anti-microbial activity of test compounds was found to be active against all organisms. Additionally, anti-inflammatory activity of the test groups has reduced the thickness of edema of the hind paw compared to the control group.

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피인용 문헌

  1. Structure Elucidation of New Flavone and Antioxidant, Anti-Inflammatory Activities from Leaves of Vitex negundo Linn. vol.32, pp.5, 2017, https://doi.org/10.14233/ajchem.2020.22519
  2. Genus Calotropis: A Hub of Medicinally Active Phytoconstituents vol.6, pp.4, 2017, https://doi.org/10.2174/2215083805666190619095933
  3. Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE i vol.12, pp.1, 2022, https://doi.org/10.1039/d1ra07221h