DOI QR코드

DOI QR Code

Microwave Dielectric Absorption Spectroscopy Aiming at Novel Dosimetry Using DNAs

  • Received : 2015.07.17
  • Accepted : 2016.11.28
  • Published : 2017.03.31

Abstract

Background: We are developing L-band and S-band microwave dielectric absorption systems aiming novel dosimetry using DNAs, such as plasmid DNA and genomic DNA, and microwave technology. Materials and Methods: Each system is composed of a cavity resonator, analog signal generator, circulator, power meter, and oscilloscope. Since the cavity resonator is sensitive to temperature change, we have made great efforts to prevent the fluctuation of temperature. We have developed software for controlling and measurement. Results and Discussion: By using this system, we can measure the resonance frequency, f, and ${\Delta}Q$ (Q is a dimensionless parameter that describes how under-damped an oscillator or resonator is, and characterizes a resonator's bandwidth relative to its center frequency) within about 3 minutes with high accuracy. Conclusion: This system will be expected to be applicable to DNAs evaluations and to novel dosimetric system.

Keywords

References

  1. Ledoux M. Nuclear engineering handbook, Chap. 25. 2nd Ed. Boca Raton, FL. CRC Press. 2015;913-916.
  2. Tsoulfanidis N, Landsberger S. Measurement & detection of radiation, Chap. 16.9. 4th Ed. Boca Raton, FL. CRC Press. 2015;503-512.
  3. Woods PJ, Pikaev AK. Applied radiation chemistry: Radiation processing, Chap. 4. 1st Ed. New York, NY. John Wiley & Sons. 1994;90-125.
  4. Grigas J. Microwave dielectric spectroscopy of ferroelectrics and related materials, Chap. 3. 1st Ed. Amsterdam, Netherland. Gordon and Breach Publishers. 1996;23-46.
  5. Hirayama M., Matuo Y., Sunagawa T., Izumi Y., Evaluation of DNA damage using microwave dielectric absorption spectroscopy, J. Radiat. Prot. Res. 2016;41(4):339-343. https://doi.org/10.14407/jrpr.2016.41.4.339