생물정신의학 (Korean Journal of Biological Psychiatry)

  • 제24권4호
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  • Pages.167-174
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  • 2017
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  • 1225-8709(pISSN)
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  • 2005-7571(eISSN)
대한생물정신의학회 (The Korean Society of Biological Psychiatry)
권호 표지

정신질환에서 뇌자극술의 적용

The Application of Brain Stimulation in Psychiatric Disorders : An Overview

  • 노대영 (한림대학교 의과대학 춘천성심병원 정신건강의학교실) ;
  • 강리영 (한림대학교 의과대학 춘천성심병원 정신건강의학교실) ;
  • 김도훈 (한림대학교 의과대학 춘천성심병원 정신건강의학교실)
  • Roh, Daeyoung (Department of Psychiatry, Hallym University College of Medicine, Chuncheon Sacred Heart Hospital) ;
  • Kang, Lee Young (Department of Psychiatry, Hallym University College of Medicine, Chuncheon Sacred Heart Hospital) ;
  • Kim, Do Hoon (Department of Psychiatry, Hallym University College of Medicine, Chuncheon Sacred Heart Hospital)
  • 투고 : 2017.06.09
  • 심사 : 2017.07.26
  • 발행 : 2017.11.30
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초록

Based on advances in biotechnology and neuroscience, neuromodulation is poised to gain clinical importance as a treatment modality for psychiatric disorders. In addition to old-established electroconvulsive therapy (ECT), clinicians are expected to understand newer forms of neurostimulation, such as deep brain stimulation (DBS), vagus nerve stimulation (VNS), repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS). Given the growing interest in non-invasive neuromodulation technologies, clinicians may seek sufficient information about neuromodulation to inform their clinical practice. A growing literature suggests that applications of non-invasive neuromodulation have evidence particularly for indications where treatments are currently insufficient, such as drug-resistant depression. However, positive neuromodulation studies require replication, and the precise interactions among stimulation, antidepressant medication, and psychotherapy are unknown. Further studies of long-term safety and the impact on the developing brain are needed. Non-invasive neuromodulatory devices could enable more individualized treatment. However, do-it-yourself (DIY) stimulation kits require a better understanding of the effects of more frequent patterns of stimulation and raise concerns about clinical supervision, regulation, and reimbursement. Wide spread enthusiasm for therapeutic potential of neuromodulation in clinical practice settings should be mitigated by the fact that there are still research gaps and challenges associated with non-invasive neuromodulatory devices.

키워드

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