Biomolecules & Therapeutics

  • 제25권2호
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  • Pages.91-104
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  • 2017
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  • 1976-9148(pISSN)
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  • 2005-4483(eISSN)
한국응용약물학회 (The Korean Society of Applied Pharmacology)
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Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders

  • Kim, Hyun Pyo (College of Pharmacy, Kangwon National University) ;
  • Lim, Hyun (College of Pharmacy, Kangwon National University) ;
  • Kwon, Yong Soo (College of Pharmacy, Kangwon National University)
  • 투고 : 2016.08.18
  • 심사 : 2016.10.04
  • 발행 : 2017.03.01
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⟨ 이전 논문 다음 논문 ⟩

초록

Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These include coumarins, flavonoids, phenolics, iridoids, monoterpenes, diterpenes and triterpenoids. Some of them exerted inhibitory action mainly by inhibiting the mitogen-activated protein kinase pathway and nuclear transcription $factor-{\kappa}B$ activation. Especially, many flavonoid derivatives distinctly showed effectiveness on lung inflammation. In this review, the experimental data for plant extracts and their constituents showing therapeutic effectiveness on animal models of lung inflammation are summarized.

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참고문헌

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  3. Aurantio-obtusin, an anthraquinone from cassiae semen, ameliorates lung inflammatory responses vol.32, pp.8, 2018, https://doi.org/10.1002/ptr.6082
  4. Anti-Inflammatory and Anti-Oxidant Activity of Portulaca oleracea Extract on LPS-Induced Rat Lung Injury vol.24, pp.1, 2019, https://doi.org/10.3390/molecules24010139
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  8. Pharmacologic Activities of Plant-Derived Natural Products on Respiratory Diseases and Inflammations vol.2021, pp.None, 2021, https://doi.org/10.1155/2021/1636816
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  10. Herbal Medicine Compared to Placebo for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis vol.12, pp.None, 2017, https://doi.org/10.3389/fphar.2021.717570
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