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A comparative study of established z score models for coronary artery diameters in 181 healthy Korean children

  • Ryu, Kyungguk (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Yu, Jeong Jin (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jun, Hyun Ok (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shin, Eun Jung (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Heo, Young Hee (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Baek, Jae Suk (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Young-Hwue (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Ko, Jae-Kon (Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine)
  • Received : 2017.07.28
  • Accepted : 2017.09.21
  • Published : 2017.11.15

Abstract

Purpose: The aim of this study was to investigate the statistical properties of four previously developed pediatric coronary artery z score models in healthy Korean children. Methods: The study subjects were 181 healthy Korean children, whose age ranged from 1 month to 15 years. The diameter of each coronary artery was measured using 2-dimensional echocardiography and converted to the z score in the four models (McCrindle, Olivieri, Dallaire, and Japanese model). Descriptive statistical analyses and 1-sample t tests were performed. Results: All calculated z scores had P values of ${\geq}0.050$ using the Kolmogorov-Smirnov test. The one sample t test showed that the mean z scores did not converge to zero except in 1 model, and the mean right coronary artery (RCA) z score was less than zero in all 4 models. The smaller RCA diameter in this study could be associated with the more distal measuring point used to avoid the conal branch. The percentage of subjects with extreme z score values (${\geq}2.0$ and ${\geq}2.5$) for the left main coronary artery (LMCA) seems to be higher in the Dallaire (4.9% and 3.3%) and Japanese models (7.1% and 3.8%). Conclusion: All 4 models showed statistical feasibility of normal distribution. More precise instructions would be needed for the measurement of the RCA. The higher percentage of extreme z scores for the LMCA is compatible with the basic understanding of anatomic variation in the LMCA.

Keywords

References

  1. Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi 1967;16:178-222.
  2. McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association. Circulation 2017;135:e927-99.
  3. Suzuki A, Kamiya T, Kuwahara N, Ono Y, Kohata T, Takahashi O, et al. Coronary arterial lesions of Kawasaki disease: cardiac catheterization findings of 1100 cases. Pediatr Cardiol 1986;7:3-9. https://doi.org/10.1007/BF02315475
  4. Newburger JW, Takahashi M, Burns JC, Beiser AS, Chung KJ, Duffy CE, et al. The treatment of Kawasaki syndrome with intravenous gamma globulin. N Engl J Med 1986;315:341-7. https://doi.org/10.1056/NEJM198608073150601
  5. Dajani AS, Taubert KA, Takahashi M, Bierman FZ, Freed MD, Ferrieri P, et al. Guidelines for long-term management of patients with Kawasaki disease. Report from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 1994; 89:916-22. https://doi.org/10.1161/01.CIR.89.2.916
  6. Durongpisitkul K, Gururaj VJ, Park JM, Martin CF. The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment. Pediatrics 1995;96:1057-61.
  7. Japan Kawasaki Disease Research Committee. Report of subcommittee on standardization of diagnostic criteria and reporting of coronary artery lesions in Kawasaki disease. Tokyo: Ministry of Health and Welfare; 1984.
  8. de Zorzi A, Colan SD, Gauvreau K, Baker AL, Sundel RP, Newburger JW. Coronary artery dimensions may be misclassified as normal in Kawasaki disease. J Pediatr 1998;133:254-8. https://doi.org/10.1016/S0022-3476(98)70229-X
  9. Epstein ML, Goldberg SJ, Allen HD, Konecke L, Wood J. Great vessel, cardiac chamber, and wall growth patterns in normal children. Circulation 1975;51:1124-9. https://doi.org/10.1161/01.CIR.51.6.1124
  10. Kurotobi S, Nagai T, Kawakami N, Sano T. Coronary diameter in normal infants, children and patients with Kawasaki disease. Pediatr Int 2002;44:1-4. https://doi.org/10.1046/j.1442-200X.2002.01508.x
  11. Tan TH, Wong KY, Cheng TK, Heng JT. Coronary normograms and the coronary-aorta index: objective determinants of coronary artery dilatation. Pediatr Cardiol 2003;24:328-35. https://doi.org/10.1007/s00246-002-0300-7
  12. McCrindle BW, Li JS, Minich LL, Colan SD, Atz AM, Takahashi M, et al. Coronary artery involvement in children with Kawasaki disease: risk factors from analysis of serial normalized measurements. Circulation 2007;116:174-9. https://doi.org/10.1161/CIRCULATIONAHA.107.690875
  13. Olivieri L, Arling B, Friberg M, Sable C. Coronary artery Z score regression equations and calculators derived from a large heterogeneous population of children undergoing echocardiography. J Am Soc Echocardiogr 2009;22:159-64. https://doi.org/10.1016/j.echo.2008.11.003
  14. Dallaire F, Dahdah N. New equations and a critical appraisal of coronary artery Z scores in healthy children. J Am Soc Echocardiogr 2011;24:60-74. https://doi.org/10.1016/j.echo.2010.10.004
  15. Kobayashi T, Fuse S, Sakamoto N, Mikami M, Ogawa S, Hamaoka K, et al. A new Z score curve of the coronary arterial internal diameter using the Lambda-Mu-Sigma method in a pediatric population. J Am Soc Echocardiogr 2016;29:794-801.e29. https://doi.org/10.1016/j.echo.2016.03.017
  16. Yu JJ, Cho SK, Park YM, Lee R, Chung S, Bae SH. Coronary artery diameter of normal children aged 3 months to 6 years. Korean J Pediatr 2008;51:629-33. https://doi.org/10.3345/kjp.2008.51.6.629
  17. Haycock GB, Schwartz GJ, Wisotsky DH. Geometric method for measuring body surface area: a height-weight formula validated in infants, children, and adults. J Pediatr 1978;93:62-6. https://doi.org/10.1016/S0022-3476(78)80601-5
  18. Quinones MA, Otto CM, Stoddard M, Waggoner A, Zoghbi WA; Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr 2002;15:167-84. https://doi.org/10.1067/mje.2002.120202
  19. Seo JH, Yu JJ, Ko HK, Choi HS, Kim YH, Ko JK. Diagnosis of incomplete Kawasaki disease in infants based on an inflammation at the Bacille Calmette-Guerin inoculation site. Korean Circ J 2012;42:823-9. https://doi.org/10.4070/kcj.2012.42.12.823

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