The Korean Journal of Community Living Science (한국지역사회생활과학회지)

The Korean Society of Community Living Science (한국지역사회생활과학회)
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Evaluation of Antioxidant, Anti-Inflammatory, Antithrombotic, and Antiobesity Activities in Cultured Edible Plants to Increase Farm Income

농가소득 창출을 위한 식용식물의 항산화, 항염, 항혈전 및 항비만 효과 탐색

  • Lee, Seon-Hye (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Kim, Nam-Seok (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Choi, Bong-Kyoum (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Park, Yeon-Hee (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Kim, Jung-Bong (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Jang, Hwan-Hee (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Hwang, Yu-Jin (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Choe, Jeong-Sook (Dept. of Agrofood Resources, Rural Development Administration) ;
  • Lee, Sung-Hyen (Dept. of Agrofood Resources, Rural Development Administration)
  • 이선혜 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 김남석 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 최봉겸 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 박연희 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 김정봉 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 장환희 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 황유진 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 최정숙 (농촌진흥청 국립농업과학원 기능성식품과) ;
  • 이성현 (농촌진흥청 국립농업과학원 기능성식품과)
  • Received : 2016.09.20
  • Accepted : 2017.01.12
  • Published : 2017.02.28
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Abstract

We studied the antioxidant, the anti-inflammatory, antithrombotic, and antiobesity activities of seven different kinds of edible plants. 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ABTS radical scavenging activities were determined as a measurement of antioxidant activity. NO production inhibition by the macrophage cell line (Raw 264.7) treated with lipopolysaccharide (LPS) was carried out to assess anti-inflammatory activity. Thrombin inhibitory activity was measured for its antithrombotic function and inhibition of 3T3-L1 cell differentiation was evaluated as a measurement of antiobesity activity. Total phenolic components and total flavonoid contents were measured to determine functional materials in medicinal plants. Common sage, Japanese lady bell, and hairy agrimony showed high antioxidant activity ($IC_{50}$) of less than $100{\mu}g/mL$. All samples used in this study showed anti-inflammatory activity. Common sage, hairy agrimony, and hooker chives showed antithrombotic effects. Hairy agrimony showed the highest antithrombotic effect (98.1%). Common sage, Japanese lady belly, hairy agrimony, and hooker chives showed reduced 3T3-L1 cell differentiation and hooker chives strongly inhibited lipid accumulation in the cells compared to other medicinal plants. Common sage and hairy agrimony contained more than 1 mg GAE/g of phenolic compounds and more than 1 mg CE/g of flavonoids. Functional activities were different by plant part and extraction method from each sample. These results suggest that common sage, Japanese lady belly, hairy agrimony, and hooker chives may be used as healthy food sources with antioxidant, anti-inflammatory, antithrombotic, and antiobesity activities, and appropriate extracting methods from each plant need to be developed.

Keywords

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