Fisheries and Aquatic Sciences

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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Biological activities and biomedical potential of sea cucumber (Stichopus japonicus): a review

  • Oh, Gun-Woo (Department of Biomedical Engineering, and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University) ;
  • Ko, Seok-Chun (Marine-Integrated Bionics Research Center, Pukyong National University) ;
  • Lee, Dong Hee (Gyeongbuk Institute for Bio industry) ;
  • Heo, Soo-Jin (Jeju International Marine Science Center for Research & Education, Korea Institute of Ocean Science and Technology) ;
  • Jung, Won-Kyo (Department of Biomedical Engineering, and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University)
  • Received : 2017.07.10
  • Accepted : 2017.09.26
  • Published : 2017.11.30
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Abstract

Members of the phylum Echinodermata, commonly known as echinoderms, are exclusively marine invertebrates. Among the Echinodermata, sea cucumber belongs to the family Holothuroidea. The sea cucumber Stichopus (Apostichous) japonicus (Selenka) is an invertebrate animal inhabiting the coastal sea around Korean, Japan, China, and Russia. Sea cucumber has a significant commercial value, because it contains valuable nutrients such as vitamins and minerals. They possess a number of distinctive biologically and pharmacologically important compounds. In particular, the body wall of sea cucumber is a major edible part. It consists of peptide, collagen, gelatin, polysaccharide, and saponin, which possess several biological activities such as anti-cancer, anti-coagulation, anti-oxidation, and anti-osteoclastogenesis. Furthermore, the regenerative capacity of sea cucumber makes it a medically important organism. This review presents the various biological activities and biomedical potential of sea cucumber S. japonicus.

Keywords

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