Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)

Korean Society for Clinical Laboratory Science (대한임상검사과학회)
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Epidemiologic Study of Zoophilic Dermatophytoses between 2010 and 2016

2010~2016년 동안 동물친화성 피부 사상균 감염의 역학적 연구

  • Kim, Su Jung (Department of Biomedical Laboratory Science, Daegu Health College)
  • 김수정 (대구보건대학교 임상병리과)
  • Received : 2017.10.18
  • Accepted : 2017.11.09
  • Published : 2017.12.31
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Abstract

In recent years, change in life patterns gave rise to an increase in the number of families with companion animals, and as a result, frequent dermatophytes infections have been reported. Microsporum canis, Trichophyton mentagrophytes, and Trichophyton verrucosum, are among these species of zoophilic dermatophytes. Trichophyton mentagrophytes are transmitted to humans by contact with wild animals. Infection from it causes strong inflammation in humans. Conversely, Trichophyton verrucosum is transmitted by contact with cattles. Microsporum canis will become latent carriers in cats or dogs, causing infectious diseases when it comes in contact with humans. We investigated zoophilic dermatophytes isolated according to annual, sex, age, season, body sites, and clinical types between 2010 and 2016. According to our results, the isolation rate of zoophilic dermatophytes was 0.37%, among which, 88 T. mentagrophytes, 228 Microsporum canis, and 18 Trichophyton verrucosum were isolated in human. It is interesting to note that Microsporum canis has been on the rise since 2014. Microsporum canis and Trichophyton verrucosum were highly isolated in females, but T. mentagrophytes was isolated similarly in both sexes. According to an age-based survey, the isolation rate was higher in children younger than 10 years. Our results is a valuable data for predicting and studying the isolation of zoophilic dermatophytes in the future.

2010~2016년에 병원을 내원한 환자를 대상으로 분석 결과 전체 분리균은 인체 친화성 감염환자는 33,575명으로 37.24%가 분리되었으며 동물친화성 감염환자는 334명으로 0.37%가 분리되었다. 토양친화성 감염환자는 30명으로 0.03%가 분리되었고 그 외에 배양이 되지 않거나 오염균이 56,217명(62.35%)으로 분리되었다. 동물친화성 피부사상균을 대상으로 남녀 성별에 따른 분포를 살펴 본 결과 T. mentagrophytes는 남자(51.1%), 여자(48.9%)가 분리되었기에 성별에 연관성이 거의 없었으나 T. verrucosum은 남자(38.9%)에 비해 여자(61.1%)가 다소 높게 분리되었다. M. canis는 남자(23.7%)에 비해 여자(76.3%)가 분리율이 높게 나타났다. 연령에 따른 분석 결과 T. mentagrophytes는 50대(26.4%), 60대(16.1%)에 높게 분리되었고 T. verrucosum은 50대(27.8%), 60대(16.7%), 그리고 10대 미만(16.7%)의 순서로 분포하였다. M. canis는 10대 미만(19.4%), 10대(22.0%), 그리고 20대(15.0%)의 순서로 분리되었다. 계절에 따른 분석 결과 T. mentagrophytes는 봄(34.1%), 겨울(29.5%)에 높게 분리되었고 T. verrucosum은 봄(44.4%), 겨울(27.8%)에 높게 분리되었다. M. canis는 봄(18.9%), 여름(27.2%), 가을(25.9%), 그리고 겨울(28.1%)에 비슷하게 분리되었다. 이는 T. mentagrophytes와 T. verrucosum은 계절에 따라 연관성을 보이나 M. canis는 계절에 따른 연관성이 나타나지 않았다. 부위에 따른 분석 결과로 T. mentagrophytes는 얼굴(28.4%), 팔(25.0%)에서 높게 분리되었으며 T. verrucosum도 얼굴(38.9%), 팔(27.8%)에서 높게 분리되었다. 그러나 M. canis는 다소 다양하게 머리(24.5%), 팔(21.5%), 얼굴(15.8%), 등(12.7%) 등의 순으로 분리되었다. 임상 질환별 분석 결과 T. mentagrophytes는 몸백선증(48.9%)이 많이 분리되었고 다음으로 얼굴백선증(28.4%), 수부백선증(11.4%)으로 분리되었다. T. verrucosum는 몸백선증(55.6%)이 가장 많이 분리되었고 얼굴백선증(38.9%)이 분리되었다. M. canis는 몸백선증(54.4%)이 가장 많이 분리되었고 두부백선증(24.5%), 얼굴백선증(15.8%)의 순서로 분리되었다. 본 조사를 통해 동물친화성 감염의 분포의 변화를 확인하였으며 향후 지속적인 자료수집을 통해 동물친화성 감염의 분포 추이를 조사함에 도움이 될 것으로 사료된다.

Keywords

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  1. 소아에서 분리된 피부진균증의 발생경향 vol.50, pp.4, 2017, https://doi.org/10.15324/kjcls.2018.50.4.444