DOI QR코드

DOI QR Code

공명각 및 반사광 측정 모드에서 다양한 물질 구성의 표면 플라즈몬 공명 센서 칩의 민감도 특성

A Study on the Sensitivity of Surface Plasmon Resonance Sensor Chips with Various Material Configurations in Angle and Intensity Detection Modes

  • 손영수 (대구가톨릭대학교 의공학과)
  • Sohn, Young-Soo (Department of Biomedical Engineering, Daegu Catholic Unversity)
  • 투고 : 2017.11.06
  • 심사 : 2017.11.23
  • 발행 : 2017.11.30

초록

Characteristics of various material surface plasmon resonance (SPR) chips were investigated in angular interrogation mode and intensity interrogation mode. Among five metals, silver (Ag), gold (Au), copper (Cu), chromium (Cr) and titanium (Ti), three metals, Ag, Au and Cu were paid attention to since their characteristics can be easily analyzed in angular interrogation mode by investigating the change of their reflectance curves according to refractive index change from 1.331 to 1.335. Most of SPR chips with various configurations showed the similar property in angular interrogation mode. The application of the SPR chip made of Ag, Au and Cu or their combinations depends on their reflectance properties. In intensity interrogation mode, the operation range may be limited since the variation of the intensity was not linearly related to refractive index change ranging from 1.331 to 1.335. However, the SPR chip containing high ratio of Ag may be applicable to high sensitive detection due to their sharp reflectance curves in intensity interrogation mode.

키워드

참고문헌

  1. J. Homola, "Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species", Chem. Rev. Vol. 108, No. 2 pp. 462-493, 2008 https://doi.org/10.1021/cr068107d
  2. J. Ashley, M. Piekarska, C. Segers, L. Trinh, T. Rodgers, and R. Willey, "An SPR based sensor for allergens detection", Biosens. Bioelectron. Vol. 88, pp. 109-113, 2017 https://doi.org/10.1016/j.bios.2016.07.101
  3. Y. K. Lee, K.-S. Lee, W. M. Kim, and Y.-S. Sohn, "Detection of Amyloid-${\beta}42$ Using a Waveguide-Coupled Bimetallic Surface Plasmon Resonance Sensor Chip in the Intensity Measurement Mode", PLoS One, Vol. 9, No. 6, p. e98992, 2014. https://doi.org/10.1371/journal.pone.0098992
  4. A. R. Sadrolhosseini, M. Naseri, and H. M. Kamari, "Surface plasmon resonance sensor for detecting of arsenic in aqueous solution using polypyrrole-chitosan-cobalt ferrite nanoparticles composite layer", Opt. Commun. Vol. 383, pp. 132-137, 2017. https://doi.org/10.1016/j.optcom.2016.08.065
  5. A. Aube, D. M. Charbonneau, J. N. Pelletier, and J.-F. Masson, "Response Monitoring of Acute Lymphoblastic Leukemia Patients Undergoing I-Asparaginase Theraphy: Successes and Challenges Associated with Clinical Sample Analysis in Plasmonic Sensing", ACS Sensors, Vol. 1, No. 11, pp. 1358-1365, 2016 https://doi.org/10.1021/acssensors.6b00531
  6. J. Breault-Turcot, H.-P. Poirier-Richard, M. Couture,a D. Pelechacz and J.-F. Masson, "Single chip SPR and fluorescent ELISA assay of prostate specific antigen", Lab Chip, Vol. 15, No. 23, pp.4433-4440, 2015 https://doi.org/10.1039/C5LC01045D
  7. S. A. Meyer, E. C. Le Ru, and P. G. Etchegoin, "Combining Surface Plasmon Resonance (SPR) Spectroscopy with Surface-Enhanced Raman Scattering (SERS)", Anal. Chem. Vol. 83, No. 6, pp. 2337-2344, 2011 https://doi.org/10.1021/ac103273r
  8. E. Kretschmann, "Decay of non radiative surface plasmons into light on rough silver films. Comparison of experimental and theoretical results", Opt. Commun. Vol. 6, Issue 2, pp. 185-187, 1972. https://doi.org/10.1016/0030-4018(72)90224-6
  9. F.-C. Chien, and S.-J. Chen, "A sensitivity comparison of optical biosensors based on four different surface plasmon resonance modes", Biosens. Bioelectron. Vol. 20, Issue 3, pp. 633-642, 2004. https://doi.org/10.1016/j.bios.2004.03.014
  10. P. B. Johnson and R. W. Christy, "Optical Constants of the Noble Metals", Phy. Rev. B Vol. 6, No. 12, pp. 4370-4379, 1972. https://doi.org/10.1103/PhysRevB.6.4370
  11. http://corninfo.ps.uci.edu/calculations.html (retrieved on Oct. 8, 2017)
  12. Y. K. Lee, D. H. Jang, K.-S. Lee, W. M. Kim and Y.-S. Sohn, "Enhancing performance of a miniaturized surface plasmon resonance sensor in the reflectance detection mode using a waveguide-coupled bimetallic chip", Nanoscale Res. Lett., Vol. 8 p. 344, 2013. https://doi.org/10.1186/1556-276X-8-344
  13. S. Chen, and C. Lin, "High-performance bimetallic film surface plasmon resonancesensor based on film thickness optimization", Optik, Vol. 127, pp. 7514-7519, 2016. https://doi.org/10.1016/j.ijleo.2016.05.085