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What Are the Optimal Dose of Administration and Time of Drainage for Topical Tranexamic Acid in Patients Undergoing Cardiac Surgery?

  • Nouraei, Seyed Mahmood (Thoracic and Cardiovascular Surgery Department, Faculty of Medicine, Mazandaran University of Medical Sciences)
  • Received : 2017.06.01
  • Accepted : 2017.08.10
  • Published : 2017.12.05

Abstract

Keywords

References

  1. Dhir A. Antifibrinolytics in cardiac surgery. Ann Card Anaesth 2013;16:117-25. https://doi.org/10.4103/0971-9784.109749
  2. Nouraei M, Baradari AG, Ghafari R, Habibi MR, Zeydi AE, Sharifi N. Decreasing blood loss and the need for transfusion after CABG surgery: a double-blind randomized clinical trial of topical tranexamic acid. Turk J Med Sci 2013;43:273-8.
  3. Patel J, Prajapati M, Patel H, Gandhi H, Deodhar S, Pandya H. Topical and low-dose intravenous tranexamic acid in cyanotic cardiac surgery. Asian Cardiovasc Thorac Ann 2017;25:118-22. https://doi.org/10.1177/0218492316688416
  4. Taksaudom N, Siwachat S, Tantraworasin A. Additional effects of topical tranexamic acid in on-pump cardiac surgery. Asian Cardiovasc Thorac Ann 2017;25:24-30. https://doi.org/10.1177/0218492316683759
  5. Kimenai DM, Gerritse BM, Lucas C, et al. Effectiveness of pericardial lavage with or without tranexamic acid in cardiac surgery patients receiving intravenous tranexamic acid: a randomized controlled trial. Eur J Cardiothorac Surg 2016;50:1124-31. https://doi.org/10.1093/ejcts/ezw214
  6. Ali Shah MU, Asghar MI, Siddiqi R, Chaudhri MS, Janjua AM, Iqbal A. Topical application of tranexamic acid reduces postoperative bleeding in open-heart surgery: myth or fact? J Coll Physicians Surg Pak 2015;25:161-5.
  7. Gofton TE, Chu MW, Norton L, et al. A prospective observational study of seizures after cardiac surgery using continuous EEG monitoring. Neurocrit Care 2014;21:220-7. https://doi.org/10.1007/s12028-014-9967-x

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