Korean Chemical Engineering Research

  • 제55권6호
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  • Pages.791-797
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  • 2017
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  • 0304-128X(pISSN)
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  • 2233-9558(eISSN)
한국화학공학회 (The Korean Institute of Chemical Engineers)
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PEO-PPO-PEO 블록 공중합체를 이용한 PDMS의 친수성 표면 개질 방법

Surface Modification of PDMS for Hydrophilic and Antifouling Surface Using PEO-PPO-PEO Block Copolymer

  • 투고 : 2017.04.15
  • 심사 : 2017.08.04
  • 발행 : 2017.12.01
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⟨ 이전 논문 다음 논문 ⟩

초록

본 연구에서는 Poly (dimethylsiloxane) (PDMS)의 높은 소수성과 생체분자들의 비특이적 흡착 문제를 해결하기 위해 PEO-PPO-PEO 블록 공중합체의 포매(embeddeing) 방식을 이용하여 손쉬운 표면 개질 및 이의 최적화 조건을 조사하였다. 친수성 표면 개질의 특성은 PDMS 내에 포매된 블록 공중합체의 농도, 수침(water-soaking), 및 소수성 표면으로 회복 시간 등의 영향을 평가하였다. 개질된 PDMS 표면은 알부민 단백질(2 mg/ml)까지 단백질의 비특이적 결합 방지 특성을 보였으며, 또한 O/W (Oil-in-Water) 에멀젼을 쉽게 형성할 수 있었다.

In this study, we optimized a method of PEO-PPO-PEO block copolymer embedding, for solving non-specific protein and biomolecular adsorption and high hydrophobicic surface property, which is widely known as problems of poly (dimethylsiloxane) (PDMS) that has frequently been used in basic biological and its applied research. We assessed its surface modification by controlling the concentration of embedded block copolymer, water-soaking time, and recovery time as variables by contact angle measurements. In order to evaluate its antifouling ability, adsorption of FITC-BSA molecules was quantified. Furthermore, we generated oil-in-water (O/W) emulsion as a proof-of-concept experiment to confirm that the optimized surface modification works properly.

키워드

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