The Journal of the Korean dental association (대한치과의사협회지)

The Korean Dental Association (대한치과의사협회)
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Pathogens and Their Antimicrobial Susceptibilities of Endodontic Infection in Type II Diabetes Mellitus Patients

제 2형 당뇨 환자의 근관 감염에서 나타난 병원균과 그 항생제 감수성

  • Cho, Ju-Yeon (Department of Dentistry, Keimyeong University Dongsan Medical Center) ;
  • Kim, Sung-Kyo (Department of Conservative Dentistry, Kyngpook National University Hospital)
  • 조주연 (계명대학교 의과대학 동산의료원 치과) ;
  • 김성교 (경북대학교 치과대학병원 치과보존과)
  • Received : 2015.10.30
  • Accepted : 2016.01.25
  • Published : 2016.05.01
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Abstract

Aim: The purpose of this study was to identify dominant pathogens and their antimicrobial susceptibilities of endodontic infection in type II diabetes mellitus (DM) patients to determine effective empirical antibiotics. Methodology: Pathogens from endodontic infection in six patients with DM and in six patients without DM were cultured, identified and their antimicrobial susceptibility was tested using Vitek2 systems ($bioM{\acute{e}}rieux$, Marcy l' Etoile, France). The results were analyzed using Chi-square test and Fisher's exact test at P< 0.05 level. Results: Pathogens of opportunistic infection were dominant in DM patients (P=0.015). However, there was no significant difference of antimicrobial susceptibility between DM and non-DM patients. Relatively high percent (27%) of pathogens showed resistance to penicillin. Conclusions: More cautions should be paid to DM patients because they are prone to opportunistic infection. Penicillin is not effective in the control of endodontic infection.

Keywords

Acknowledgement

Supported by : 계명대학교

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