Journal of Korean Foot and Ankle Society (대한족부족관절학회지)

Korean Foot & Ankle Society (대한족부족관절학회)
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The Amputation Rate and Associated Risk Factors within 1 Year after the Diagnosis of Diabetic Foot Ulcer

당뇨병성 족부 궤양 환자의 진단 1년 내의 절단율 및 위험 인자의 분석

  • Chun, Dong-Il (Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital) ;
  • Jeon, Min Chul (Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital) ;
  • Choi, Sung-Woo (Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital) ;
  • Kim, Yong-Beom (Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital) ;
  • Nho, Jae-Hwi (Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital) ;
  • Won, Sung Hun (Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital)
  • 천동일 (순천향대학교 서울병원 정형외과) ;
  • 전민철 (순천향대학교 서울병원 정형외과) ;
  • 최성우 (순천향대학교 서울병원 정형외과) ;
  • 김용범 (순천향대학교 서울병원 정형외과) ;
  • 노재휘 (순천향대학교 서울병원 정형외과) ;
  • 원성훈 (순천향대학교 서울병원 정형외과)
  • Received : 2016.06.30
  • Accepted : 2016.08.01
  • Published : 2016.09.15
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Abstract

Purpose: This study investigates the amputation rate within 1 year after the diagnosis of diabetic foot ulcer and its associated risk factors. Materials and Methods: This study enrolled 60 patients with diabetic foot ulcer. The mean and standard deviation age was $64.4{\pm}12.8years$ (range, 32~89 years); the mean and standard deviation prevalence period for diabetes mellitus was $21.0{\pm}7.5years$ (range, 0.5~36 years). The amputation rate was evaluated by dividing the subjects into two groups - the major and minor amputation groups - within 1 year following the initial diagnosis of diabetic foot ulcer. Multivariate Cox proportional hazards regression analysis was used to identify the risk factors for amputation. Results: The total amputation rate of 38.3% (n=23) was comprised of the amputation rate for the major amputation group (10.0%) and rate for the minor amputation group (23.8%). There was a high correlation between peripheral artery disease (toe brachial pressure index <0.7) and amputation (hazard ratio [HR] 5.81, confidence interval [CI] 2.09~16.1, p<0.01). Nephropathy was significantly correlated with the amputation rate (HR 3.53, CI 1.29~9.64, p=0.01). Conclusion: Clinicians who treat patients with diabetic foot complications must understand the fact that the amputation rate within 1 year is significant, and that the amputation rate of patients with peripheral artery disease or nephropathy is especially high.

Keywords

References

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