Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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A Preliminary Study of Childhood Trauma and Patterns of Psychotropic Medication Use in Patients with Schizophrenia

조현병 환자의 아동기 외상과 정신작용약물 사용 경향에 대한 예비 연구

  • Kim, Chonggi (Department of Psychiatry, Hanyang Univesity Medical Center) ;
  • Kim, Daeho (Department of Psychiatry, Hanyang Univesity Medical Center) ;
  • Lee, Hyunji (Industry-University Cooperation Foundation, Hanyang University) ;
  • Kim, Yangsuk (San Diego Psychoanalytic Center)
  • 김총기 (한양대학교 의료원 정신건강의학과) ;
  • 김대호 (한양대학교 의료원 정신건강의학과) ;
  • 이현지 (한양대학교 산학협력단) ;
  • 김양석 (샌디에고 정신분석센터)
  • Received : 2016.06.16
  • Accepted : 2016.06.20
  • Published : 2016.08.31
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Abstract

Objectives Experience of early childhood abuse elevates the risk of developing schizophrenia in later period of life, incidence of psychiatric comorbidity, symptomatic severity and complexity. In this context, we hypothesized that the pattern of psychotropic medication used would reflect this; those with childhood trauma will received more types and higher doses of psychotropic medication. Methods From our database of 102 outpatients diagnosed with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) schizophrenia, we analyzed experiences of childhood trauma measured by the Childhood Trauma Questionnaire-Short Form and types and dose of prescribed psychotropic medication. Results We found significant positive correlations between child sexual abuse and the number of psychotropic medications (p = 0.029) and between child emotional neglect and the number of psychotropic medications other than antipsychotics (p = 0.045). Conclusions This preliminary study suggests that the pattern of psychotropic use may be affected by types of childhood trauma. Further studies will have to shed light on mediating factors such as symptoms or comorbid conditions that lead to prescription of certain psychotropic class.

Keywords

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