참고문헌
- Chung K, Wallace J, Kim S Y, Kalyanasundaram S, Andalman A S, Davidson T J, Mirzabekov J J, Zalocusky K A, Mattis J, Denisin A K, Pak S, Bernstein H, Ramakrishnan C, Grosenick L, Gradinaru V, and Deisseroth K (2013) Structural and molecular interrogation of intact biological systems. Nature 497, 332-337. https://doi.org/10.1038/nature12107
- Gong H, Zeng S, Yan C, Lv X, Yang Z, Xu T, Feng Z, Ding W, Qi X, Li A, Wu J, and Luo Q (2013) Continuously tracing brain-wide long distance axonal projections in mice at a one-micron voxel resolution. Neuroimage 74, 87-98. https://doi.org/10.1016/j.neuroimage.2013.02.005
- Hama H, Kurokawa H, Kawano H, Ando R, Shimogori T, Noda H, Fukami K, Sakaue-Sawano A, and Miyawaki A (2011) Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain. Nat. Neurosci. 14, 1481-1488. https://doi.org/10.1038/nn.2928
- Helmchen F and Denk W (2005) Deep tissue two-photon microscopy. Nat. Methods 12, 932-940.
- Kanda T, Tsujino N, Kuramoto E, Koyama Y, Susaki E A, Chikahisa S, and Funato H (2016) Sleep as a biological problem: an overview of frontiers in sleep research. J. Physiol. Sci. 66, 1-13. https://doi.org/10.1007/s12576-015-0414-3
- Kim S Y, Cho J H, Murray E, Bakh N, Choi H, Ohn K, Ruelas L, Hubbert A, McCue M, Vassallo S L, Keller P J, and Chung K (2015) Stochastic electrotransport selectively enhances the transport of highly electromobile molecules. Proc. Natl. Acad. Sci. U S A 112, E6274-E6283. https://doi.org/10.1073/pnas.1510133112
- Ke M T, Fujimoto S, and Imai T (2013) SeeDB: a simple and morphologypreserving optical clearing agent for neuronal circuit reconstruction. Nat. Neurosci. 16, 1154-1161. https://doi.org/10.1038/nn.3447
- Kim H W, Kim D S, and Rhyu I J (2014) Electron tomography and synapse study. Appl. Microsc. 44, 83-87. https://doi.org/10.9729/AM.2014.44.3.83
- Kurihara D, Mizuta Y, Sato Y, and Higashiyama T (2015) ClaerSee: a rapid optical clearing reagent for whole-plant fluorescence imaging. Dev. Camb. Engl. 142, 4168-4179.
- Lee E, Choi J, Jo Y, Kim J Y, Jang Y J, Lee H M, Kim S Y, Lee H J, Cho K, Jung N, Hur E M, Jeong S J, Moon C, Choe Y, Rhyu I J, Kim H, and Sun W (2016a) ACT-PRESTO: rapid and consistent tissue clearing and labeling method for 3-dimensional (3D) imaging. Sci. Rep. 6, 18631. https://doi.org/10.1038/srep18631
- Lee E, Kim H J, and Sun W (2016b) See-through technology for biological tissue: 3-dimensional visualization of macromolecules. Int. Neurourol. J. 20, S15-S22. https://doi.org/10.5213/inj.1632630.315
- Li A, Gong H, Zhang B, Wang Q, Yan C, Wu J, Liu Q, Zeng S, and Luo Q (2010) Micro-optical sectioning tomography to obtain a highresolution atlas of the mouse brain. Science 330, 1404-1408. https://doi.org/10.1126/science.1191776
- Liebmann T, Renier N, Bettayeb K, Greengard P, Tessier-Lavigne M, and Flajolet M (2016) Three-dimensional study of Alzheimer's disease hallmarks using the iDISCO clearing method. Cell Rep. 26, 1138-1152.
- Murray E, Cho J H, Goodwin D, Ku T, Swaney J, Kim S Y, Choi H, Park Y G, Park J Y, Hubbert A, McCue M, Vassallo S, Bakh N, Frosch M P, Wedeen V J, Seung H S, and Chung K (2015) Simple, scalable proteomic imaging for high-dimensional profiling of intact systems. Cell 163, 1500-1514. https://doi.org/10.1016/j.cell.2015.11.025
- Palmer W M, Martin A P, Flynn J R, Reed S L, White R G, Furbank R T, and Grof C P L (2015) PEA-CLARITY: 3D molecular imaging of whole plant organs. Sci. Rep. 5, 13492. https://doi.org/10.1038/srep13492
- Renier N, Wu Z, Simon D J, Yang J, Ariel P, and Tessier-Lavigne M (2014) iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging. Cell 159, 896-910. https://doi.org/10.1016/j.cell.2014.10.010
- Seo J, Choe M, and Kim S Y (2016) Clearing and labeling techniques for large-scale biological tissues. Mol. Cells 39, 439-446. https://doi.org/10.14348/molcells.2016.0088
- Susaki E A, Tainaka K, Perrin D, Kishino F, Tawara T, Watanabe T M, Yokoyama C, Onoe H, Eguchi M, Yamaguchi S, Abe T, Kiyonari H, Shimizu Y, Miyawaki A, Yokota H, and Ueda H R (2014) Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis. Cell 157, 726-739. https://doi.org/10.1016/j.cell.2014.03.042
- Tainaka K, Kubota S I, Suyama T Q, Susaki E A, Perrin D, Ukai-Tadenuma M, Ukai H, and Ueda H R (2014) Whole-body imaging with single-cell resolution by tissue decolorization. Cell 159, 911-924. https://doi.org/10.1016/j.cell.2014.10.034
- Tang J, Germain R N, and Cui M (2012) Superpenetration optical microscopy by iterative multiphoton adaptive compensation technique. Proc. Natl. Acad. Sci. U S A 109, 8434-8439. https://doi.org/10.1073/pnas.1119590109
- Tomer R, Ye L, Hsueh B, and Deisseroth K (2014) Advanced CLARITY for rapid and high-resolution imaging of intact tissues. Nat. Protoc. 9, 1682-1697. https://doi.org/10.1038/nprot.2014.123
- Yang B, Treweek J B, Kulkarni R P, Deverman B E, Chen C K, Lubeck E, Shah S, Cai L, and Gradinaru V (2014) Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell 158, 945-958. https://doi.org/10.1016/j.cell.2014.07.017