References
- Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, Eckel RH; American Heart Association; Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006;113:898-918. https://doi.org/10.1161/CIRCULATIONAHA.106.171016
- Wang Z, Nakayama T. Inflammation, a link between obesity and cardiovascular disease. Mediators Inflamm 2010;2010:535918.
- Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, Eckel RH. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss. Arterioscler Thromb Vasc Biol 2006;26:968-76. https://doi.org/10.1161/01.ATV.0000216787.85457.f3
- Mathieu P, Poirier P, Pibarot P, Lemieux I, Despres JP. Visceral obesity: the link among inflammation, hypertension, and cardiovascular disease. Hypertension 2009;53:577-84. https://doi.org/10.1161/HYPERTENSIONAHA.108.110320
- Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006;444:875-80. https://doi.org/10.1038/nature05487
- Boeing H, Bechthold A, Bub A, Ellinger S, Haller D, Kroke A, Leschik-Bonnet E, Müller MJ, Oberritter H, Schulze M, Stehle P, Watzl B. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr 2012;51:637-63. https://doi.org/10.1007/s00394-012-0380-y
- Joshipura KJ, Hu FB, Manson JE, Stampfer MJ, Rimm EB, Speizer FE, Colditz G, Ascherio A, Rosner B, Spiegelman D, Willett WC. The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med 2001;134:1106-14. https://doi.org/10.7326/0003-4819-134-12-200106190-00010
- Holt EM, Steffen LM, Moran A, Basu S, Steinberger J, Ross JA, Hong CP, Sinaiko AR. Fruit and vegetable consumption and its relation to markers of inflammation and oxidative stress in adolescents. J Am Diet Assoc 2009;109:414-21. https://doi.org/10.1016/j.jada.2008.11.036
- Bazzano LA, Serdula MK, Liu S. Dietary intake of fruits and vegetables and risk of cardiovascular disease. Curr Atheroscler Rep 2003;5:492-9. https://doi.org/10.1007/s11883-003-0040-z
- Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption. J Agric Food Chem 2006;54:4069-75. https://doi.org/10.1021/jf060300l
- Zafra-Stone S, Yasmin T, Bagchi M, Chatterjee A, Vinson JA, Bagchi D. Berry anthocyanins as novel antioxidants in human health and disease prevention. Mol Nutr Food Res 2007;51:675-83. https://doi.org/10.1002/mnfr.200700002
- Prior RL, Wilkes SE, Rogers TR, Khanal RC, Wu X, Howard LR. Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet. J Agric Food Chem 2010;58:3970-6. https://doi.org/10.1021/jf902852d
- Riso P, Klimis-Zacas D, Del Bo' C, Martini D, Campolo J, Vendrame S, Møller P, Loft S, De Maria R, Porrini M. Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors. Eur J Nutr 2013;52:949-61. https://doi.org/10.1007/s00394-012-0402-9
- Serraino I, Dugo L, Dugo P, Mondello L, Mazzon E, Dugo G, Caputi AP, Cuzzocrea S. Protective effects of cyanidin-3-O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure. Life Sci 2003;73:1097-114. https://doi.org/10.1016/S0024-3205(03)00356-4
- Gopalan A, Reuben SC, Ahmed S, Darvesh AS, Hohmann J, Bishayee A. The health benefits of blackcurrants. Food Funct 2012;3:795-809. https://doi.org/10.1039/c2fo30058c
- He J, Giusti MM. Anthocyanins: natural colorants with healthpromoting properties. Annu Rev Food Sci Technol 2010;1:163-87. https://doi.org/10.1146/annurev.food.080708.100754
- Chang HJ, Choi EH, Chun HS. Quantitative structure-activity relationship (QSAR) of antioxidative anthocyanidins and their glycosides. Food Sci Biotechnol 2008;17:501-7.
- Hou DX, Yanagita T, Uto T, Masuzaki S, Fujii M. Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. Biochem Pharmacol 2005;70:417-25. https://doi.org/10.1016/j.bcp.2005.05.003
- Giusti MM, Wrolstad RE. Characterization and measurement of anthocyanins by UV-visible spectroscopy. In: Current Protocols in Food Analytical Chemistry. Hoboken (NJ): John Wiley & Sons, Inc.; 2001. p.F1.2.1-13.
- Wu X, Prior RL. Systematic identification and characterization of anthocyanins by HPLC-ESI-MS/MS in common foods in the United States: fruits and berries. J Agric Food Chem 2005;53:2589-99. https://doi.org/10.1021/jf048068b
- Kim B, Ku CS, Pham TX, Park Y, Martin DA, Xie L, Taheri R, Lee J, Bolling BW. Aronia melanocarpa (chokeberry) polyphenol-rich extract improves antioxidant function and reduces total plasma cholesterol in apolipoprotein E knockout mice. Nutr Res 2013;33:406-13. https://doi.org/10.1016/j.nutres.2013.03.001
- Yang Y, Seo JM, Nguyen A, Pham TX, Park HJ, Park Y, Kim B, Bruno RS, Lee J. Astaxanthin-rich extract from the green alga Haematococcus pluvialis lowers plasma lipid concentrations and enhances antioxidant defense in apolipoprotein E knockout mice. J Nutr 2011;141:1611-7. https://doi.org/10.3945/jn.111.142109
- Benzie IF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 1996;239:70-6. https://doi.org/10.1006/abio.1996.0292
- Carr TP, Andresen CJ, Rudel LL. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 1993;26:39-42. https://doi.org/10.1016/0009-9120(93)90015-X
- Kim B, Park Y, Wegner CJ, Bolling BW, Lee J. Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells. J Nutr Biochem 2013;24:1564-70. https://doi.org/10.1016/j.jnutbio.2013.01.005
- Ku CS, Pham TX, Park Y, Kim B, Shin MS, Kang I, Lee J. Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-kappaB pathway in macrophages and splenocytes. Biochim Biophys Acta 2013;1830:2981-8. https://doi.org/10.1016/j.bbagen.2013.01.018
- Mailloux RJ, Harper ME. Uncoupling proteins and the control of mitochondrial reactive oxygen species production. Free Radic Biol Med 2011;51:1106-15. https://doi.org/10.1016/j.freeradbiomed.2011.06.022
-
Lee SG, Kim B, Yang Y, Pham TX, Park YK, Manatou J, Koo SI, Chun OK, Lee JY. Berry anthocyanins suppress the expression and secretion of proinflammatory mediators in macrophages by inhibiting nuclear translocation of NF-
${\kappa}B$ independent of NRF2-mediated mechanism. J Nutr Biochem 2014;25:404-11. https://doi.org/10.1016/j.jnutbio.2013.12.001 - Crozier A, Del Rio D, Clifford MN. Bioavailability of dietary flavonoids and phenolic compounds. Mol Aspects Med 2010;31:446-67. https://doi.org/10.1016/j.mam.2010.09.007
- Ferreira de Araujo PR, da Silva Santos V, Rodrigues Machado A, Gevehr Fernandes C, Silva JA, da Silva Rodrigues R. Benefits of blackberry nectar (Rubus spp.) relative to hypercholesterolemia and lipid peroxidation. Nutr Hosp 2011;26:984-90.
- Prior RL, Wu X, Gu L, Hager T, Hager A, Wilkes S, Howard L. Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet. Mol Nutr Food Res 2009;53:1406-18. https://doi.org/10.1002/mnfr.200900026
- Perseghin G. Muscle lipid metabolism in the metabolic syndrome. Curr Opin Lipidol 2005;16:416-20. https://doi.org/10.1097/01.mol.0000174401.07056.56
- Jia Y, Kim JY, Jun HJ, Kim SJ, Lee JH, Hoang MH, Kim HS, Chang HI, Hwang KY, Um SJ, Lee SJ. Cyanidin is an agonistic ligand for peroxisome proliferator-activated receptor-alpha reducing hepatic lipid. Biochim Biophys Acta 2012;1831:698-708.
- Um MY, Ahn J, Ha TY. Hypolipidaemic effects of cyanidin 3-glucoside rich extract from black rice through regulating hepatic lipogenic enzyme activities. J Sci Food Agric 2013;93:3126-8. https://doi.org/10.1002/jsfa.6070
- Wei X, Wang D, Yang Y, Xia M, Li D, Li G, Zhu Y, Xiao Y, Ling W. Cyanidin-3-O-beta-glucoside improves obesity and triglyceride metabolism in KK-Ay mice by regulating lipoprotein lipase activity. J Sci Food Agric 2011;91:1006-13. https://doi.org/10.1002/jsfa.4275
- Vitaglione P, Donnarumma G, Napolitano A, Galvano F, Gallo A, Scalfi L, Fogliano V. Protocatechuic acid is the major human metabolite of cyanidin-glucosides. J Nutr 2007;137:2043-8. https://doi.org/10.1093/jn/137.9.2043
- Lin CY, Huang CS, Huang CY, Yin MC. Anticoagulatory, antiinflammatory, and antioxidative effects of protocatechuic acid in diabetic mice. J Agric Food Chem 2009;57:6661-7. https://doi.org/10.1021/jf9015202
- Ohman MK, Shen Y, Obimba CI, Wright AP, Warnock M, Lawrence DA, Eitzman DT. Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice. Circulation 2008;117:798-805. https://doi.org/10.1161/CIRCULATIONAHA.107.717595
- Gustafson B. Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb 2010;17:332-41. https://doi.org/10.5551/jat.3939
- Wajchenberg BL, Nery M, Cunha MR, Silva ME. Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis. Arq Bras Endocrinol Metabol 2009;53:145-50. https://doi.org/10.1590/S0004-27302009000200005
- Coenen KR, Gruen ML, Chait A, Hasty AH. Diet-induced increases in adiposity, but not plasma lipids, promote macrophage infiltration into white adipose tissue. Diabetes 2007;56:564-73. https://doi.org/10.2337/db06-1375
- Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-808. https://doi.org/10.1172/JCI200319246
- Amano SU, Cohen JL, Vangala P, Tencerova M, Nicoloro SM, Yawe JC, Shen Y, Czech MP, Aouadi M. Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation. Cell Metab 2014;19:162-71. https://doi.org/10.1016/j.cmet.2013.11.017
- Zhu Y, Ling W, Guo H, Song F, Ye Q, Zou T, Li D, Zhang Y, Li G, Xiao Y, Liu F, Li Z, Shi Z, Yang Y. Anti-inflammatory effect of purified dietary anthocyanin in adults with hypercholesterolemia: a randomized controlled trial. Nutr Metab Cardiovasc Dis 2013;23:843-9. https://doi.org/10.1016/j.numecd.2012.06.005
- Prior RL, Wu X. Anthocyanins: structural characteristics that result in unique metabolic patterns and biological activities. Free Radic Res 2006;40:1014-28. https://doi.org/10.1080/10715760600758522
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