DOI QR코드

DOI QR Code

The Difference of Health Related Quality of Life According to Ankylosing Spondylitis Patient's General Characteristics

강직척추염 환자의 일반적 특성에 따른 건강관련 삶의 질 차이

  • Jang, Ae Ri (Department of nursing Songwon University) ;
  • Jang, Keum Seong (College of Nursing, Chonnam National University.Chonnam Research Institute of Nursing Science)
  • 장애리 (송원대학교 간호학과) ;
  • 장금성 (전남대학교 간호대학.간호과학연구소)
  • Received : 2016.07.13
  • Accepted : 2016.08.11
  • Published : 2016.08.31

Abstract

This study was conducted to identify differences between qualities of health related to quality of life according to the general characteristics of ankylosing spondylitis patients. Overall, 275 patients who were older than 19 years, drug-maintained for over 4 weeks from Jan 13th to Feb 12th and diagnosed as ankylosing spondylitis at C university hospital participated in this study. Collected data were analyzed through descriptive statistics, t-tests, ANOVA, Scheffe's-test and multiple regression. The results of the present study revealed that Age (p=.008), Job (p<0.001), Number of comorbidity (p<0.001), Surgery for Ankylosing Spondylitis (p=0.002), Disease duration after onset symptom (p=0.010), Disease duration after diagnosis (p=0.027), Alcohol drinking (p=0.002) and Erythrocyte sedimentation rate (p=0.049) were meaningful factors to the quality of health-related life for ankylosing spondylitis patients, and multiple regression analysis showed that level of education, income, comorbidity and alcohol consumption was a significant variable. In conclusion, the results of this study indicated that, to improve quality of life, arbitration programs for improving general characteristics and considering demographic social characteristics and clinical features need to be provided. Therefore, it is expected that the results of this study would be used as actual grounds to develop integrated arbitration programs.

본 연구는 강직척추염 환자의 일반적 특성에 따른 건강관련 삶의 질의 차이를 알아보기 위한 서술조사연구이다. 연구대상은 2015년 1월 13일부터 2월 12일까지 G광역시 C대학병원에 강직척추염으로 진단받고 최소 4주이상의 안정적인 약물을 유지중인 만 19세 이상의 환자를 대상으로 설문조사를 통해 자료를 수집하였으며 총 275명의 자료가 분석에 포함되었다. 수집된 자료는 기술적 통계, t-test, ANOVA, Scheff-test, multiple regression를 통해 분석하였다. 연구 결과 연령(p=.008), 직업유무(p<0.001), 동반질환 수(p<0.001), 수술유무(p=0.002), 증상 발현 후 기간(p=0.010), 진단 후 기간(p=0.027), 음주(p=0.002), 적혈구 침강속도(p=0.049)는 강직척추염 환자의 건강관련 삶의 질에 유의하게 영향을 미치는 것으로 분석되었으며, 다중회귀분석 결과 교육수준, 수입, 동반질환 수, 음주가 유의미한 변수였다. 결론적으로 강직척추염 환자의 건강관련 삶을 향상시키기 위해 일반적 특성을 개선시킬 수 있는 중재 프로그램을 개발함과 동시에 인구사회학적 특징과, 임상학적 특성을 고려한 중재프로그램이 제공되어야 할 필요가 있음을 알 수 있다. 따라서 본 연구의 결과가 이러한 통합적인 중재프로그램 개발에 실제적인 근거로 활용 될 수 있을 것으로 생각된다.

Keywords

References

  1. Korea Ankylosin Spodylitis Corporation. Ankylosing Spondylitis[Internet]. Seoul: Korea Ankylosin Spodylitis Corporation; 2015. Available from: http://www.gidarlim.com/(accessed Jun., 10, 2015)
  2. Joel DT. HARRISON'S Principles of Internal Medicine Vol2. 16th Edition. p.2175-217, Seoul: MIP Publishers, 2006.
  3. Gran JT, Husby G. Ankylosing Spondylitis: a comparative study of patients in an epidemiological survey, and those admitted to a department of rheumatology, Journal of Rheumatology, vol. 11, no. 6 pp. 788-793, Dec, 1984.
  4. Disease Act Statistics in Government 3.0 Information disclosure [Internet]. Seoul: Health Insurance Review & Assessment Service; 2015 [cited 2015 May]. Available from: http://www.hira.or.kr/rd/dissdicinfoSickList.do?pgmid=HIRAA0200440/20100. (accessed Jun., 11, 2015)
  5. Lee TJ, Park BH, Kim JW, Shin K, Lee EB, Song YW. Cost-of-illness and quality of life in patients with ankylosing spondylitis at a tertiary hospital in Korea, J Korean Med Sci, vol. 29, no. 2 pp.190-197, Feb, 2014. DOI: http://dx.doi.org/10.3346/jkms.2014.29.2.190
  6. Khan MA, van der Linden SM. A wider spectrum of spondyloarthropathies, Semin Arthritis Rheum, vol. 20, pp.107-113, 1990. DOI: http://dx.doi.org/10.1016/0049-0172(90)90023-9
  7. Sieper J. Rudwaleit M, Khan MA, Braun J. Concepts and epidemiology of spondyloarthritis, Best Pract Res Clin Rheumatol, vol. 20, pp.401-417, 2006. DOI: http://dx.doi.org/10.1016/j.berh.2006.02.001
  8. Kim TJ, Kim TH. Clinical spectrum of ankylosing spondylitis in Korea, Joint Bone Spine, vol. 77, pp.235-240, 2010. DOI: http://dx.doi.org/10.1016/j.jbspin.2009.11.015
  9. Shin KC. Clinical Manifestation and Diagnosis of Ankylosing Spondylitis, The Korean Association of Internal Medicine. vol. 85, no. 3, pp.240-244, 2013. DOI: http://dx.doi.org/10.3904/kjm.2013.85.3.240
  10. Kim TJ. Quality of life in ankylosing spondylitis[master's thesis], Seoul: Hanyang University, pp.1-36, 2002.
  11. Ibn Yacoub Y, Amine B, Laatiris A, Hajjaj-Hassouni N. Gender and disease features in Moroccan patients with ankylosing spondylitis, Clin Rheumatol, vol. 31, no. 2, pp.293-297, Feb, 2012. DOI: http://dx.doi.org/10.1007/s10067-011-1819-x
  12. Chen CH, Chen HA, Lu CL, Liao HT, Liu CH, Tsai CY, et al. Association of cigarette smoking with Chinese ankylosing spondylitis patients in Taiwan: a poor disease outcome in systemic inflammation, functional ability, and physical mobility, Clin Rheumatol, vol. 32, no. 5, pp.659-663, May, 2013. DOI: http://dx.doi.org/10.1007/s10067-013-2165-y
  13. Mattey DL, Dawson SR, Healey EL, Packham JC. Relationship between smoking and patient-reported measures of disease outcome in ankylosing spondylitis, J Rheumatol, vol. 39, no. 12, pp.2608-2615, Dec, 2011. DOI: http://dx.doi.org/10.3899/jrheum.110641
  14. Chung HY, Machado P, van der Heijde D, D'Agostino MA, Dougados M. Smokers in early axial spondyloarthritis have earlier disease onset, more disease activity, inflammation and damage, and poorer function and health-related quality of life: results from the DESIR cohort. Ann Rheum Dis, vol. 71, no. 6, pp.809-816, Jun, 2012. DOI: http://dx.doi.org/10.1136/annrheumdis-2011-200180
  15. Braun J, Sieper J, Zink A. The risks of smoking in patients with spondyloarthritides, Ann Rheum Dis, vol. 71, no. 6, pp.791-792, Jun, 2012. DOI: http://dx.doi.org/10.1136/annrheumdis-2011-200954
  16. Marengo MF, Schneeberger EE, Citera G, Cocco JA. Work status among patients with ankylosing spondylitis in Argentina, J Clin Rheumatol, vol. 14, no. 5, pp. 273-277, Oct, 2008. DOI: http://dx.doi.org/10.1097/RHU.0b013e31817d1089
  17. Vesovic-Potic V, Mustur D, Stanisavljevic D, Ille T, Ille M. Relationship between spinal mobility measures and quality of life in patients with ankylosing spondylitis, Rheumatol Int, vol. 29, no. 8, pp. 879-884, Jun, 2009. DOI: http://dx.doi.org/10.1007/s00296-008-0759-5
  18. Kiltz U, van der Heijde D. Health-related quality of life in patients with rheumatoid arthritis and in patients with ankylosing spondylitis, Clin Exp Rheumatol, vol. 27, no. 4, Suppl.55 pp.S108-111, Jul-Aug, 2009.
  19. Yu JP. Structural equation modeling misunderstandings and prejudices of professors Jong Pil Yu. Data solution: Hannarae publishing corporation; 2014.
  20. Choi JH, Jung HJ, Oh TR, Lee SH, Jin J, Lee JW, et al. The Reliability and Validity of a Korean Translation of the ASAS Health Index and Environmental Factors in Korean Patients with Axial Spondyloarthritis. The Journal of the Korean Rheumatism Association, vol. 29, no. 3, pp.334-337, 2014. DOI: http://dx.doi.org/10.3346/jkms.2014.29.3.334
  21. Ovayolu N, Ovayolu O, Karadag G. Health-related quality of life in ankylosing spondylitis, fibromyalgia syndrome, and rheumatoid arthritis: a comparison with a selected sample of healthy individuals, Clin Rheumatol, vol. 30, no. 5, pp.655-664, May, 2011. DOI: http://dx.doi.org/10.1007/s10067-010-1604-2
  22. Yilmaz O, Tutoglu A, Garip Y, Ozcan E, Bodur H. Health-related quality of life in Turkish patients with ankylosing spondylitis: impact of peripheral involvement on quality of life in terms of disease activity, functional status, severity of pain, and social and emotional functioning, Rheumatol Int, vol. 33, no. 5, pp.1159-1163, May, 2013. DOI: http://dx.doi.org/10.1007/s00296-012-2510-5
  23. Durcan L, Wilson F, Conway R, Cunnane G, O'Shea FD. Increased body mass index in ankylosing spondylitis is associated with greater burden of symptoms and poor perceptions of the benefits of exercise, J Rheumatol, vol. 39, no. 12, pp.2310-2314. Dec, 2012. DOI: http://dx.doi.org/10.3899/jrheum.120595