Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Middle East Respiratory Syndrome-Coronavirus Infection: A Case Report of Serial Computed Tomographic Findings in a Young Male Patient

  • Choi, Won Jin (Department of Radiology, Dong-A University Hospital) ;
  • Lee, Ki-Nam (Department of Radiology, Dong-A University Hospital) ;
  • Kang, Eun-Ju (Department of Radiology, Dong-A University Hospital) ;
  • Lee, Hyuck (Division of Infectious Diseases, Department of Internal Medicine, Dong-A University Hospital)
  • Received : 2015.07.02
  • Accepted : 2015.11.01
  • Published : 2016.02.01
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Abstract

Radiologic findings of Middle East respiratory syndrome (MERS), a novel coronavirus infection, have been rarely reported. We report a 30-year-old male presented with fever, abdominal pain, and diarrhea, who was diagnosed with MERS. A chest computed tomographic scan revealed rapidly developed multifocal nodular consolidations with ground-glass opacity halo and mixed consolidation, mainly in the dependent and peripheral areas. After treatment, follow-up imaging showed that these abnormalities markedly decreased but fibrotic changes developed.

Keywords

References

  1. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012;367:1814-1820 https://doi.org/10.1056/NEJMoa1211721
  2. Ajlan AM, Ahyad RA, Jamjoom LG, Alharthy A, Madani TA. Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings. AJR Am J Roentgenol 2014;203:782-787 https://doi.org/10.2214/AJR.14.13021
  3. Das KM, Lee EY, Enani MA, AlJawder SE, Singh R, Bashir S, et al. CT correlation with outcomes in 15 patients with acute Middle East respiratory syndrome coronavirus. AJR Am J Roentgenol 2015;204:736-742 https://doi.org/10.2214/AJR.14.13671
  4. Corman VM, Eckerle I, Bleicker T, Zaki A, Landt O, Eschbach-Bludau M, et al. Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction. Euro Surveill 2012;17. pii: 20285
  5. Alagaili AN, Briese T, Mishra N, Kapoor V, Sameroff SC, Burbelo PD, et al. Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia. Mbio 2014;5:e00884-14. http://dx.doi.org/10.1128/mbio.00884-14
  6. Centers for Disease Control and Prevention. Notice to health care providers: updated guidelines for evaluation of severe respiratory illness associated with Middle East respiratory syndrome coronavirus (MERS-CoV). http://emergency.cdc.gov/HAN/han00348.asp. Published June 7, 2013. Accessed June 22, 2015
  7. World Health Organization. MERS-CoV in the Republic of Korea at a glance. http://www.wpro.who.int/outbreaks_emergencies/wpro_coronavirus/en/. Published June 22, 2015. Accessed June 22, 2015
  8. Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A, et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis 2013;13:752-761 https://doi.org/10.1016/S1473-3099(13)70204-4
  9. Das KM, Lee EY, Jawder SE, Enani MA, Singh R, Skakni L, et al. Acute Middle East respiratory syndrome coronavirus: temporal lung changes observed on the chest radiographs of 55 patients. AJR Am J Roentgenol 2015;23:W1-W8

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