Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지
DOI QR코드

DOI QR Code

Clinical and Echocardiographic Findings for Dilated Cardiomyopathy Induced by Taurine Deficiency in a Cat

  • An, Su-Jin (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Jang, Hyo-Mi (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Lee, Hee-Chun (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University) ;
  • Jung, Dong-In (Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University)
  • Received : 2016.07.12
  • Accepted : 2016.08.16
  • Published : 2016.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

A 6-year-old male domestic shorthair cat was referred to Gyeongsang National University Animal Medical Center for labored breathing. According to the patient's history, the client had fed him commercial dog foods. The patient's hematological, radiographic, and echocardiographic examinations were evaluated for diagnosis. Echocardiography results showed marked dilations of ventricles and atriums and mitral regurgitation. A systolic dysfunction was detected. Plasma taurine concentration was lower than the reference range. Based on these results, the patient was diagnosed with feline dilated cardiomyopathy associated with taurine deficiency. Treatment included feline commercial foods, taurine, digoxin, furosemide, and clopidogrel. Digoxin was changed to pimobendan when normal blood pressure was achieved. Clinical signs improved gradually and no abnormalities were detected on echocardiograms at 10 weeks following onset of treatment.

Keywords

References

  1. Agarwal A, Amsterdam EA. Too much of a good thing: digitalis toxicity. Am J Med 2015; 128: 257-259. https://doi.org/10.1016/j.amjmed.2014.11.009
  2. Amstrong PJ, Gross KL, Becvarova I, Debraekeleeer J. Introduction to feeding normal cats. In: Small Animal Clinical Nutrition, 5th ed. Mark Morris institute. 2010: 368-369.
  3. Baral RM, Little SE. Cardiovascular disease. In: The Cat: Clinical Medicine and Management, 1st ed. St Louis: Elsevier Saunders. 2012: 250.
  4. Bartges J. The unique nutritional requirements of the cat: A strict carnivore. In: The Cat: Clinical Medicine and Management, 1st ed. St Louis: Elsevier Saunders. 2012: 238-239.
  5. Committee CS. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet 1996; 348: 1329-1339. https://doi.org/10.1016/S0140-6736(96)09457-3
  6. Ferasin L, Sturgess C. Cannon M, Caney S, Gruffydd-Jones T, Wotton P. Feline idiopathic cardiomyopathy: a retrospective study of 106 cats (1994-2001). J Feline Med Surg 2003; 5: 151-159. https://doi.org/10.1016/S1098-612X(02)00133-X
  7. Fuentes VL. Ultrasound imaging for diagnosis and staging of feline cardiomyopathy. In: August's Consultations in Feline Internal Medicine volume 7, 1st ed. St Louis: Elsevier. 2016: 452-456
  8. Gheorghiade M, Adams KF, Colucci WS. Digoxin in the management of cardiovascular disorders. Circulation 2004; 109: 2959-2964. https://doi.org/10.1161/01.CIR.0000132482.95686.87
  9. Gordon SG, Saunders AB, Roland RM, Winter RL, Drourr L, Achen SE, Hariu CD, Fries RC, Boggess MM, Miller MW. Effect of oral administration of pimobendan in cats with heart failure. J Am Vet Med Assoc 2012; 241: 89-94. https://doi.org/10.2460/javma.241.1.89
  10. Hambrook LE, Bennett PF. Effect of pimobendan on the clinical outcome and survival of cats with non-taurine responsive dilated cardiomyopathy. J Feline Med Surg 2012; 14: 233-239. https://doi.org/10.1177/1098612X11429645
  11. Kanakubo K, Fascetti AJ, Larsen JA. Assessment of protein and amino acid concentrations and labeling adequacy of commercial vegetarian diets formulated for dogs and cats. J Am Vet Med Assoc 2015; 247: 385-392. https://doi.org/10.2460/javma.247.4.385
  12. MacDonald K. Myocardial disease: Feline. In: Textbook of Veterinary Internal Medicine, 7th ed. St Louis: Saunders Elsevier. 2010: 1328-1337.
  13. Mellett AM, Nakamura RK, Bianco D. A prospective study of clopidogrel therapy in dogs with primary immune-mediated hemolytic anemia. J Vet Intern Med 2011; 25: 71-75. https://doi.org/10.1111/j.1939-1676.2010.0656.x
  14. Meurs KM. Genetics of feline heart disease. In: August's Consultations in Feline Internal Medicine volume 7, 1st ed. St Louis: Elsevier. 2016: 412
  15. Novotny MJ, Hogan PM, Flannigan G. Echocardiographic evidence for myocardial failure induced by taurine deficiency in domestic cats. Can J Vet Res 1994; 58: 6-12.
  16. O'Grady M R. Feline dilated cardiomyopathy. Can Vet J 1987; 28: 564-565.
  17. Pion PD, Kittleson MD, Rogers QR, Morris JG. Myocardial failure in cats associated with low plasma taurine: a reversible cardiomyopathy. Science 1987; 237: 764-768. https://doi.org/10.1126/science.3616607
  18. Roudebush P, Keene BW. Cardiovascular disease. In: Small Animal Clinical Nutrition, 5th ed. Mark Morris institute. 2010: 743-757.
  19. Ware WA. Myocardial disease of the cat. In: Small Animal Internal Medicine, 5th ed. St Louis: Elsevier Mosby. 2014: 155-157.