Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Bilateral iliac and popliteal arterial thrombosis in a child with focal segmental glomerulosclerosis

  • Han, Kyoung Hee (Department of Pediatrics, Jeju National University School of Medicine) ;
  • Park, Ji Youn (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Min, Seung-Kee (Department of Surgery, Seoul National University Hospital) ;
  • Ha, Il-Soo (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Cheong, Hae Il (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Kang, Hee Gyung (Department of Pediatrics, Seoul National University Children's Hospital)
  • Received : 2014.06.17
  • Accepted : 2014.08.01
  • Published : 2016.05.15
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Abstract

Thromboembolic complications (TECs) are clinically important sequelae of nephrotic syndrome (NS). The incidence of TECs in children is approximately 2%-5%. The veins are the most commonly affected sites, particularly the deep veins in the legs, the inferior vena cava, the superior vena cava, and the renal veins. Arterial thrombosis, which is less common, typically occurs in the cerebral, pulmonary, and femoral arteries, and is associated with the use of steroids and diuretics. Popliteal artery thrombosis in children has been described in cases of traumatic dissection, osteochondroma, Mycoplasma pneumoniae infection, and fibromuscular dysplasia. We report of a 33-month-old girl with bilateral iliac and popliteal arterial thrombosis associated with steroid-resistant NS due to focal segmental glomerulosclerosis. Her treatment involved thrombectomy and intravenous heparinization, followed by oral warfarin for 8 months. Herein, we report a rare case of spontaneous iliac and popliteal arterial thrombosis in a young child with NS.

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References

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