대한한방소아과학회지 (The Journal of Pediatrics of Korean Medicine)

  • 제30권3호
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  • Pages.52-60
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  • 2016
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  • 1226-8038(pISSN)
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  • 2287-9463(eISSN)
대한한방소아과학회 (The Association of Korean Oriental Pediatrics)
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국소한약외용제의 알레르기성 비염 치료 효과에 대한 문헌 고찰

A Literature Study of Topical Application of Chinese Herbal Medicine for Allergic Rhinitis

  • 방미란 (동국대학교 한의과대학 소아과교실) ;
  • 김장현 (동국대학교 한의과대학 소아과교실) ;
  • 민상연 (동국대학교 한의과대학 소아과교실)
  • Bang, Mi Ran (Department of Pediatrics, College of Oriental Medicine, Dongguk University) ;
  • Kim, Jang Hyun (Department of Pediatrics, College of Oriental Medicine, Dongguk University) ;
  • Min, Sang Yeon (Department of Pediatrics, College of Oriental Medicine, Dongguk University)
  • 투고 : 2016.07.22
  • 심사 : 2016.08.16
  • 발행 : 2016.08.31
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초록

Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: "allergic rhinitis", "traditional Chinese medicine", "traditional Korean medicine", "Chinese herbal medicine", "randomized controlled trial", "clinical study", "nasal spray", and "nasal drop" Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.

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참고문헌

  1. Hong CE. Textbook of pediatrics. 10th ed. Seoul: Miraen Publising co. 2012:1144-50.
  2. Kim KB, Kim DG, Kim YH, Kim JH, Min SY, Park EJ, Baek JH, Yu SA, Lee SY, Lee JY, Lee HJ, Chang GT, Chai JW, Han YJ, Han JK. Pediatrics of Korean medicine. First Volume. Seoul: Eui Seong Dang Publishing co. 2015:359-60.
  3. Schatz M. A survey of the burden of allergic rhinitis in the USA. Allergy. 2007;62Suppl85:9-16. https://doi.org/10.1111/j.1398-9995.2007.01548.x
  4. Ozdoganoglu T, Songu M, Inancli HM. Quality of life in allergic rhinitis. Ther Adv Respir Dis. 2012;6(1):25-39. https://doi.org/10.1177/1753465811424425
  5. Pawankar R, Bunnag C, Khaltaev N, Bousquet J. Allergic rhinitis and its impact on asthma in Asia pacific and the ARIA update 2008. World Allergy Organ J. 2012;5(Suppl 3):S212-7. https://doi.org/10.1186/1939-4551-5-S3-S212
  6. Huang TP, Liu PH, Lien AS, Yang SL, Chang HH, Yen HR. A nationwide population-based study of traditional Chinese medicine usage in children in Taiwan. Complement Ther Med. 2014;22(3):500-10. https://doi.org/10.1016/j.ctim.2014.04.002
  7. Li XM. Complementary and alternative medicine in pediatric allergic disorders. Curr Opin Allergy Clin Immunol. 2009;9(2):161-7. https://doi.org/10.1097/ACI.0b013e328329226f
  8. Yen HR, Liang KL, Huang TP, Fan JY, Chang TT, Sun MF. Characteristics of traditional Chinese medicine use for children with allergic rhinitis: a nationwide population-based study. Int J Pediatr Otorhinolaryngol. 2015;79(4):591-7. https://doi.org/10.1016/j.ijporl.2015.02.002
  9. Feng S, Han M, Fan Y, Yang G, Liao Z, Liao W, Li H. Acupuncture for the treatment of allergic rhinitis: a systematic review and meta-analysis. Am J Rhinol Allergy. 2015;29(1):57-62. https://doi.org/10.2500/ajra.2015.29.4116
  10. Wen CY, Liu YF, Zhou L, Zhang HX, Tu SH. A systematic and narrative review of acupuncture point application therapies in the treatment of allergic rhinitis and asthma during dog days. Evid Based Complement Alternat Med: eCAM. 2015;2015:846-51.
  11. Wu M, Zhang JY, Zhang X. Clinical observation of Flos Magnoliae Volatile oil nano-liposome nasal drops in treating pediatric allergic rhinitis. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009;29(8):740-2.
  12. Chui SH, Shek SL, Fong MY, Szeto YT, Chan K. A panel study to evaluate quality of life assessments in patients suffering from allergic rhinitis after treatment with a Chinese herbal nasal drop. Phytother Res. 2010;24(4):609-13. https://doi.org/10.1002/ptr.3058
  13. Chen XX, Fu JX, Huang J. Clinical study of curing patients with perennial allergic rhinitis by Qumin Tongbi nasal spraying agent. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011;31(5):643-6.
  14. Yuan HX. Clinical rsearch of Xinxiang Penbi Nanoemulsion in the treatment of pediatric allergic rhinitis: Nanjing University of Chinese medicine. 2015.
  15. Xiong Y. Clinical research of Qu Min nasal spray in the treatment of allergic rhinitis. J Practic Tradit Chin Med. 2015;31(04):330-1.
  16. Lisa MW, Alkis T. Allergic rhinitis. N Engl J Med. 2015;372(5):456-63. https://doi.org/10.1056/NEJMcp1412282
  17. Korean Statistical Information Service [updated 2016. 01. 13.; cited 2016. 06. 17.]. Available from: http://kosis.kr/statHtml/statHtml.do?orgId=117&tblId=DT_11702_N118&conn_path=I2.
  18. Denis K, Stephanie S. Treatment of allergic rhinitis. Am Fam Physician. 2010;12(81):1440-6.
  19. Zhang Hl, Wang Q, Zhang HM. Bibliometric analysis on randomized controlled research literatures about treating allergic rhinitis with external therapy of traditional Chinese medicine. China J Tradit Chin Med Pharm. 2015;30(9):3247-9.
  20. Lee JA, Lee MY, Seo CS, Ha H, Lee H, Kim JH, Shin HK. Asiasari sieboldii suppresses inflammatory mediators through the induction of hemeoxygenase-1 expression in RAW264.7 cells. Immunopharmacol Immunotoxicol. 2012;34(1):15-20. https://doi.org/10.3109/08923973.2011.572261
  21. Jung KY, Kim DS, Oh SR, Park SH, Lee IS, Lee JJ, Shin DH, Lee HK. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia Fargesii. J Nat Prod. 1998;61(6):808-11. https://doi.org/10.1021/np970445+
  22. Kim YJ, Lee JC, Kim HY, Xie G, Yun YG, Jang SI. Th1 and Th2 cytokine modulation by Baicalin, Baicalein and Wogonin from Scutellaria Radex on the CD4+ jurkat T Cells. J Orient Physiol Pathol. 2005; 19(4):922-7.
  23. Lee JW, Han HS, Lee YJ. Anti-inflammatory effect of Coptidis Rhizoma extract. Korean J Herbology. 2014;29(5):83-90.
  24. Shin SW, Lee YS, Park JH, Kwon TK, Seong IS, Kwon YK. Comparison of immunomodualtory effects of water-extracted Ginseng Radix, Pilose Asia-bell, Astragali Radix, Astractylodes Rhizoma Alba and Dioscoreae Rhizoma. J Orient Physiol Pathol. 2004;18(4):1140-6.
  25. Koo JS, Baek JH. A clinical study on the effect of Tongkyu-tang distillate on pediatric allergic rhinitis. J Korean Orient Pediatr. 2003;17(2):103-14.
  26. Kim JE, Hong CH. Survey on effect and satisfaction of Korean medicine distillate nasal spray of patient with chronic rhinitis. J Orient Med Ophthalmol Otolaryngol Dermatol. 2012;25(3):56-64.
  27. Kim MA, Kim MB, Ko WS, Yoon HJ. The anti-allergic effect of SESHINGO (SSG). J Orient Med Ophthalmol Otolaryngol Dermatol. 2008;21(3):69-81.
  28. Koo EJ, Han JK, Kim YH. Review of clinical studies on Korean medicine and complementary and alternative medicine treatment for allergic rhinitis in the Korean literature. J Korean Orient Pediatr. 2015;29(4):77-89. https://doi.org/10.7778/jpkm.2015.29.4.077

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