한국균학회지 (The Korean Journal of Mycology)

  • 제44권2호
  • /
  • Pages.100-102
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  • 2016
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  • 0253-651X(pISSN)
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  • 2383-5249(eISSN)
한국균학회 (The Korean Society of Mycology)
권호 표지
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Ergothioneine Contents of Shiitake (Lentinula edodes) Fruiting Bodies on Sawdust Media with Different Nitrogen Sources

  • Jang, Yeongseon (Division of Wood Chemistry & Microbiology, National Institute of Forest Science) ;
  • Park, Jiheon (Division of Wood Chemistry & Microbiology, National Institute of Forest Science) ;
  • Ryoo, Rhim (Division of Wood Chemistry & Microbiology, National Institute of Forest Science) ;
  • Park, Youngae (Division of Wood Chemistry & Microbiology, National Institute of Forest Science) ;
  • Ka, Kang-Hyeon (Division of Wood Chemistry & Microbiology, National Institute of Forest Science)
  • 투고 : 2016.06.19
  • 심사 : 2016.06.26
  • 발행 : 2016.06.30
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초록

Ergothioneine is a natural compound with strong antioxidant properties. In this study, the effects of different nitrogen sources including ammonium nitrate, ammonium sulfate, sodium nitrate, and histidine in sawdust media were investigated to enhance ergothioneine contents in Shiitake (Lentinula edodes) fruit bodies. The addition of 0.2% ammonium sulfate in the growth media showed the highest enhancement of ergothioneine content in shiitake fruit bodies which was 1.7-fold higher than the control. On the other hand, histidine, a building block of ergothioneine decreased the concentration of ergothioneine significantly. Our results demonstrate that the cultivation of shiitake in sawdust media with suitable nutrients was effective to enhance its ergothioneine contents.

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참고문헌

  1. Tanret C. New base obtained from ergot of rye. Ergothioneine. Compt Rend 1909;149:222-4.
  2. Akanmu D, Cecchini R, Aruoma OI, Halliwell B. The antioxidant action of ergothioneine. Arch Biochem Biophys 1991;288:10-6. https://doi.org/10.1016/0003-9861(91)90158-F
  3. Aruoma OI, Whiteman M, England TG, Halliwell B. Antioxidant action of ergothioneine: assessment of its ability to scavenge peroxynitrite. Biochem Biophys Res Commun 1997;231:389-91. https://doi.org/10.1006/bbrc.1997.6109
  4. Paul BD, Snyder SH. The unusual amino acid L-ergothioneine is a physiologic cytoprotectant. Cell Death Differ 2010;17:1134-40. https://doi.org/10.1038/cdd.2009.163
  5. Laurenza I, Colognato R, Migliore L, Del Prato S, Benzi L. Modulation of palmitic acid-induced cell death by ergothioneine: evidence of an anti-inflammatory action. Biofactors 2008;33:237-47. https://doi.org/10.1002/biof.5520330401
  6. Markova NG, Karaman-Jurukovska N, Dong KK, Damaghi N, Smiles KA, Yarosh DB. Skin cells and tissue are capable of using L-ergothioneine as an integral component of their antioxidant defense system. Free Radic Biol Med 2009;46:1168-76. https://doi.org/10.1016/j.freeradbiomed.2009.01.021
  7. Song TY, Chen CL, Liao JW, Ou HC, Tsai MS. Ergothioneine protects against neuronal injury induced by cisplatin both in vitro and in vivo. Food Chem Toxicol 2010;48:3492-9. https://doi.org/10.1016/j.fct.2010.09.030
  8. Cheah IK, Halliwell B. Ergothioneine; antioxidant potential, physiological function and role in disease. Biochim Biophys Acta 2012;1822:784-93. https://doi.org/10.1016/j.bbadis.2011.09.017
  9. Chang ST, Buswell JA. Mushroom nutriceuticals. World J Microbiol Biotechnol 1996;12:473-6. https://doi.org/10.1007/BF00419460
  10. Dubost NJ, Ou B, Beelman RB. Quantification of polyphenols and ergothioneine in cultivated mushrooms and correlation to total antioxidant capacity. Food Chem 2007;105:727-35. https://doi.org/10.1016/j.foodchem.2007.01.030
  11. Chang ST. World production of cultivated edible and medicinal mushrooms in 1997 with emphasis on Lentinus edodes (Berk.) Sing, in China. Int J Med Mushrooms 1999;1;291-300. https://doi.org/10.1615/IntJMedMushr.v1.i4.10
  12. Gaitan-Hernandez R, Esqueda M, Gutierrez A, Sanchez A, Beltran-Garcia M, Mata G. Bioconversion of agrowastes by Lentinula edodes: the high potential of viticulture residues. Appl Microbiol Biotechnol 2006;71:432-9. https://doi.org/10.1007/s00253-005-0241-1
  13. Lee WY, Park EJ, Ahn JK. Supplementation of methionine enhanced the ergothioneine accumulation in the Ganoderma neo-japonicum mycelia. Appl Biochem Biotechnol 2009;158:213-21. https://doi.org/10.1007/s12010-008-8322-0
  14. Lee WY, Park EJ, Ahn JK, Ka KH. Ergothioneine contents in fruiting bodies and their enhancement in mycelial cultures by the addition of methionine. Mycobiology 2009;37:43-7. https://doi.org/10.4489/MYCO.2009.37.1.043
  15. Jones GW, Doyle S, Fitzpatrick DA. The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine. Gene 2014;549:161-70. https://doi.org/10.1016/j.gene.2014.07.065
  16. Berlyn MB. Gene-enzyme relationships in histidine biosynthesis in Aspergillus nidulans. Genetics 1967;57:561-70.
  17. Liao SM, Du QS, Meng JZ, Pang ZW, Huang RB. The multiple roles of histidine in protein interactions. Chem Cent J 2013;7:44. https://doi.org/10.1186/1752-153X-7-44