Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Myelin Water Fraction MRI in a Case of Clinically Probable Amyotrophic Lateral Sclerosis

근위축성측삭경화증 환자에서의 myelin water fraction MRI 1예

  • Yang, Jiwon (Department of Neurology, Gachon University Gil Medical Center) ;
  • Lee, Jongho (Laboratory for Imaging Science and Technology (LIST), Department of Electrical and Computer Engineering, Seoul National University) ;
  • Kim, EungYeop (Department of Radiology, Gachon University Gil Medical Center) ;
  • Shin, Dong Hoon (Department of Neurology, Gachon University Gil Medical Center)
  • 양지원 (가천대학교 길병원 신경과) ;
  • 이종호 (서울대학교 전자전기공학과 바이오메디컬 영상과학연구실) ;
  • 김응엽 (가천대학교 길병원 영상의학과) ;
  • 신동훈 (가천대학교 길병원 신경과)
  • Received : 2016.01.07
  • Accepted : 2016.05.09
  • Published : 2016.06.30
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Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that clinically manifests both upper and lower motor neuron signs. However, it is unknown where and how the motor neuron degeneration begins, and conflicting hypotheses have been suggested. Recent advanced radiological techniques enable us to look into ALS neuropathology in vivo. Herein, we report a case with upper motor neuron-predominant ALS in whom the results of brain magnetic resonance imaging (MRI) and myelin water fraction MRI suggest axonal degeneration.

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References

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