Parasites, Hosts and Diseases

  • 제54권3호
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  • Pages.323-327
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  • 2016
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  • 2982-5164(pISSN)
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  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
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Painless Jaundice Caused by Clonorchis sinensis Infection: A Case Report

  • Hao, Yuhua (Infection Department, the First Hospital of Jilin University) ;
  • Bao, Wanguo (Infection Department, the First Hospital of Jilin University) ;
  • Jin, Meishan (Infection Department, the First Hospital of Jilin University) ;
  • Li, Yuxiang (Infection Department, the First Hospital of Jilin University) ;
  • Wang, Feng (Infection Department, the First Hospital of Jilin University)
  • 투고 : 2016.03.06
  • 심사 : 2016.04.16
  • 발행 : 2016.06.30
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초록

A man with only yellowing of the skin and eye sclera was diagnosed with clonorchiasis, which rarely manifested jaundice as the initial symptom. However, because of a lack of evidence for a diagnostic gold standard, the time until definitive diagnosis was more than a week. The diagnostic process relied on inquiring about the patient's history, including the place of residence, dietary habits, and symptoms, as well as on serological findings, an imaging examination, and pathological findings. MRCP and CT results showed mild dilatation of intrahepatic ducts and increased periductal echogenicity. The eggs were ultimately found in stool by water sedimentation method after the negative report through direct smear. DNA sequencing of PCR production of the eggs demonstrated 98-100% homology with ITS2 of Clonorchis sinensis. After anti-parasite medical treatment, the patient's symptoms were gradually relieved. Throughout the diagnostic procedure, besides routine examinations, the sedimentation method or concentration method could be used as a sensitive way for both light and heavy C. sinensis infection in the definite diagnosis.

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참고문헌

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  1. Clonorchiasis sinensis detected by laparoscopic exploration of biliary tracts in two patients with obstructive jaundice vol.19, pp.None, 2019, https://doi.org/10.1186/s12879-019-3679-y
  2. Acute shock caused by Clonorchis sinensis infection: a case report vol.19, pp.1, 2019, https://doi.org/10.1186/s12879-019-4644-5
  3. Surgical Infections in Low- and Middle-Income Countries: A Global Assessment of the Burden and Management Needs vol.21, pp.6, 2020, https://doi.org/10.1089/sur.2019.142
  4. Novel mechanism of hepatobiliary system damage and immunoglobulin G4 elevation caused by Clonorchis sinensis infection vol.9, pp.23, 2016, https://doi.org/10.12998/wjcc.v9.i23.6639