A Case of Fibrous Mass Diagnosed as Spidle Cell Rhabdomyosarcoma in the Vocal Fold

방추세포성 횡문근육종으로 진단된 성대 내 섬유성 종물 1예

  • Kim, Dae Young (Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine) ;
  • Hwang, Jun-Ha (Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine) ;
  • Park, In Suh (Department of Pathology, Inha University College of Medicine) ;
  • Lim, Jae-Yol (Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine)
  • 김대영 (인하대학교 의과대학 이비인후-두경부외과학교실) ;
  • 황준하 (인하대학교 의과대학 이비인후-두경부외과학교실) ;
  • 박인서 (인하대학교 의과대학 병리학교실) ;
  • 임재열 (인하대학교 의과대학 이비인후-두경부외과학교실)
  • Received : 2016.09.04
  • Accepted : 2016.09.13
  • Published : 2016.12.30

Abstract

Rhabdomyosarcoma is an uncommon type of soft tissue malignant neoplasm characterized by undifferentiated mesodermal tissue. Sarcomas account for approximately 1% of all laryngeal neoplasm and rhabdomyosarcomas are the rarest sarcoma found in the larynx. When the sarcoma involves the larynx, radical surgery such as laryngectomy has been considered. With recent advances of combined therapy, however, it can be treated by conservative surgeries followed by postoperative radiotherapy and/or pulse chemotherapy. With reviews of literature, we report a 47-year-old patient complaining of husky voice and throat discomfort who was finally diagnosed as rhabdomyosarcoma of the vocal fold and successfully treated by laser cordectomy followed by adjuvant chemoradiotherapy.

Keywords

References

  1. Raney RB, Maurer HM, Anderson JR, Andrassy RJ, Donaldson SS, Qualman SJ, et al. The Intergroup Rhabdomyosarcoma Study Group (IRSG): Major Lessons From the IRS-I Through IRS-IV Studies as Background for the Current IRS-V Treatment Protocols. Sarcoma 2001;5(1):9-15. https://doi.org/10.1080/13577140120048890
  2. Park JT, Roh JL, Kim SO, Cho KJ, Choi SH, Nam SY, et al. Prognostic factors and oncological outcomes of 122 head and neck soft tissue sarcoma patients treated at a single institution. Ann Surg Oncol 2015;22(1):248-55. https://doi.org/10.1245/s10434-014-3870-8
  3. Chang SO, Kim KH, Jin HR, Lee JW. A case of laryngeal rhabdomyosarcoma. Korean J Otolaryngol 1995;38(3):472-5.
  4. Kim SD, Kim SW, Lee SC, Kim HS, Lee YK. A case of rhabdomyosarcoma of larynx. Korean J Otolaryngol 1981;24:426-31.
  5. Feldman BA. Rhabdomyosarcoma of the head and neck. Laryngoscope 1982;92(4):424-40. https://doi.org/10.1288/00005537-198204000-00013
  6. Carroll SJ, Nodit L. Spindle cell rhabdomyosarcoma: a brief diagnostic review and differential diagnosis. Arch Pathol Lab Med 2013;137(8):1155-8. https://doi.org/10.5858/arpa.2012-0465-RS
  7. Soheila N, Nader S, Nepton EM, Mehran P. Rhabdomyosarcoma of the larynx. Pak J Med Sci 2007;23(2)280-2.
  8. Nascimento AF, Fletcher CD. Spindle cell rhabdomyosarcoma in adults. Am J Surg Pathol 2005;29(8):1106-13. https://doi.org/10.1097/00000478-200508000-00016
  9. Newton WA Jr, Gehan EA, Webber BL, Marsden HB, van Unnik AJ, Hamoudi AB, et al. Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification-an Intergroup Rhabdomyosarcoma Study. Cancer 1995;76(6):1073-85. https://doi.org/10.1002/1097-0142(19950915)76:6<1073::AID-CNCR2820760624>3.0.CO;2-L
  10. Kedar A, Kuten A, Joachims HZ, Arieh Y, Yudelev M. Rhabdomyosarcoma of the larynx treated by laser surgery combined with radiotherapy and chemotherapy. Med Pediatr Oncol 1983;11(4):279-80. https://doi.org/10.1002/mpo.2950110413