Asian Pacific Journal of Cancer Prevention

  • 제17권4호
  • /
  • Pages.2067-2073
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  • 2016
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  • 1513-7368(pISSN)
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  • 2476-762X(eISSN)
아시아태평양암예방학회 (Asian Pacific Journal of Cancer Prevention)
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Risk Factors for Cervical Cancer and CIN3 in Jewish Women in Israel - Two Case Control Studies

  • Bassal, Ravit (Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University) ;
  • Schejter, Eduardo (Women Health Center, Maccabi Healthcare Services) ;
  • Bachar, Rachel (Women Health Center, Maccabi Healthcare Services) ;
  • Perri, Tamar (Department of Gynecologic Oncology, Sheba Medical Center) ;
  • Korach, Jacob (Department of Gynecologic Oncology, Sheba Medical Center) ;
  • Jakobson-Setton, Ariella (Department of Gynecologic Oncology, Sheba Medical Center) ;
  • Ben-David, Liat Hogen (Department of Gynecologic Oncology, Sheba Medical Center) ;
  • Cohen, Daniel (Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University) ;
  • Keinan-Boker, Lital (Israel Center for Disease Control, Ministry of Health, Sheba Medical Center)
  • 발행 : 2016.06.01
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초록

Purpose: The aim of the study was to identify risk and protective factors/markers for cervical cancer and cervical intraepithelial neoplasia 3 (CIN3) in Israeli Jewish women in order to settle the discrepancy of low incidence rate of cervical cancer and relatively high incidence rate of CIN3. Materials and Methods: We conducted two case control studies, which examined the association between potential risk and protective factors/markers for cervical cancer or CIN3 using self administered detailed questionnaires. Results: For studying cervical cancer, 40 cases and 40 matched controls were interviewed. In the univariable and multivariable analyses older age, depression or anxiety and ever smoking seemed to act as independent risk factors/markers, while older age at first intercourse was protective. For studying CIN3, 99 cases and 79 controls were interviewed. Multivariable analysis has demonstrated that being born in Israel, depression or anxiety and ever smoking were independent risk factors/markers for CIN3. Conclusions: The risk factors/markers studied, that were associated with cervical cancer or CIN3 among Jewish women in Israel, are similar to those reported in other parts of the world, and do not explain the observed discrepancy of high in-situ cervical cancer rates and low invasive cervical cancer incidence in Israel.

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참고문헌

  1. Arbel-Alon S, Menczer J, Feldman N, et al (2002) Codon 72 polymorphism of p53 in Israeli Jewish cervical cancer patients and healthy women. Int J Gynecol Cancer, 12, 741-4. https://doi.org/10.1046/j.1525-1438.2002.01124.x
  2. Barton SE, Maddox PH, Jenkins D, et al (1988) Effect of cigarette smoking on cervical epithelial immunity: a mechanism for neoplastic change? Lancet, 2, 652-4.
  3. Bassal R, Rosin LS, Schvimer M, et al (2015) Prevalence and correlates of human papillomavirus genotypes among patients with cervical cancer and cervical intraepithelial neoplasia 3 in Israel. J Low Genit Tract Dis, 19, 161-4. https://doi.org/10.1097/LGT.0000000000000071
  4. Bornstein J, Rahat MA, Abramovici H (1995) Etiology of cervical cancer: current concepts. Obstet Gynecol Surv, 50, 146-54. https://doi.org/10.1097/00006254-199502000-00027
  5. Bosch FX, Lorincz A, Muñoz N, Meijer CJ, Shah, KV (2002) The causal relation between human papillomavirus and cervical cancer. J Clin Pathol, 55, 244-65. https://doi.org/10.1136/jcp.55.4.244
  6. Castle PE, Wacholder S, Lorincz AT, et al (2002) A prospective study of high-grade cervical neoplasia risk among human papillomavirus-infected women. J Natl Cancer Inst, 94, 1406-14. https://doi.org/10.1093/jnci/94.18.1406
  7. Centers for Disease Control and Prevention (CDC) (2008) Behavioral Risk Factor Surveillance System: 2005 Summary Data Quality Report.
  8. Coker AL, Bond S, Madeleine MM, Luchok K, Pirisi L (2003) Psychosocial stress and cervical neoplasia risk. Psychosom Med, 65, 644-51. https://doi.org/10.1097/01.PSY.0000041471.57895.08
  9. Cox JT (2006) Epidemiology and natural history of HPV. J Fam Pract, 3-9.
  10. Deacon JM, Evans CD, Yule R, et al (2000) Sexual behaviour and smoking as determinants of cervical HPV infection and of CIN3 among those infected: a case-control study nested within the Manchester cohort. Br J Cancer, 83, 1565-72. https://doi.org/10.1054/bjoc.2000.1523
  11. Freitas LB, Chen Z, Muqui EF, et al (2014) Human papillomavirus 16 non-European variants are preferentially associated with high-grade cervical lesions. PLoS One, 9, e100746. https://doi.org/10.1371/journal.pone.0100746
  12. Garcia-Closas R, Castellsagué X, Bosch X, González CA (2005) The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence. Int J Cancer, 117, 629-37. https://doi.org/10.1002/ijc.21193
  13. Giuntoli LR, Bristow RE (2008) Chapter 58: cervical cancer. In: Gibbs RS, Karlan BY, Haney AF, et al, editors. Danforth's obstetrics and gynecology, 10th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 971-88.
  14. Green J, Berrington de Gonzalez A, Sweetland S, et al (2003) Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK national case-control study of cervical cancer. Br J Cancer, 89, 2078-86. https://doi.org/10.1038/sj.bjc.6601296
  15. Hoyo C, Miller WC, Newman BM, Fortney JA (2000) Selective screening for cervical neoplasia: an approach for resourcepoor settings. Int J Epidemiol, 29, 807-12. https://doi.org/10.1093/ije/29.5.807
  16. Israeli Center for Disease Control (ICDC), Israeli National Cancer Registry, Ministry of Health (2015) Annual Reports. 1980-2012. http://www.health.gov.il/UNITSOFFICE/HD/ICDC/ICR/CANCERINCIDENCE/Pages/about.aspx
  17. Kirwan JM, Herrington CS (2001) Human papillomavirus and cervical cancer: where are we now? BJOG, 108, 1204-13.
  18. Kjellberg L, Hallmans G, Ahren AM, et al (2000) Smoking, diet, pregnancy and oral contraceptive use as risk factors for cervical intra-epithelial neoplasia in relation to human papillomavirus infection. Br J Cancer, 82, 1332-8. https://doi.org/10.1054/bjoc.1999.1100
  19. Le T, Hopkins L, Menard C, et al (2006) Psychologic morbidities prior to loop electrosurgical excision procedure in the treatment of cervical intraepithelial neoplasia. Int J Gynecol Cancer, 16, 1089-93. https://doi.org/10.1111/j.1525-1438.2006.00599.x
  20. Ngelangel C, Munoz N, Bosch FX, et al (1998) Causes of cervical cancer in the Philippines: a case-control study. J Natl Cancer Inst, 90, 43-9. https://doi.org/10.1093/jnci/90.1.43
  21. Pereira DB, Antoni MH, Danielson A, et al (2003) Life stress and cervical squamous intraepithelial lesions in women with human papillomavirus and human immunodeficiency virus. Psychosom Med, 65, 427-34. https://doi.org/10.1097/01.PSY.0000041620.37866.89
  22. Prokopczyk B, Cox JE, Hoffmann D, Waggoner SE (1997) Identification of tobacco-specific carcinogen in the cervical mucus of smokers and nonsmokers. J Natl Cancer Inst, 89, 868-73. https://doi.org/10.1093/jnci/89.12.868
  23. Shields TS, Brinton LA, Burk RD, et al (2004) A case-control study of risk factors for invasive cervical cancer among U.S. women exposed to oncogenic types of human papillomavirus. Cancer Epidemiol Biomarkers Prev, 13, 1574-82.
  24. Sillman F, Stanek A, Sedlis A, et al (1984) The relationship between human papillomavirus and lower genital intraepithelial neoplasia in immunosuppressed women. Am J Obstet Gynecol, 150, 300-8. https://doi.org/10.1016/S0002-9378(84)90369-7
  25. Syrjanen K, Shabalova I, Petrovichev N, et al (2007) Smoking is an independent risk factor for oncogenic human papillomavirus (HPV) infections but not for high-grade CIN. Eur J Epidemiol, 22, 723-35. https://doi.org/10.1007/s10654-007-9180-8
  26. Trevathan E, Layde P, Webster LA, et al (1983) Cigarette smoking and dysplasia and carcinoma in situ of the uterine cervix. JAMA, 250, 499-502. https://doi.org/10.1001/jama.1983.03340040039028
  27. Vigod SN, Kurdyak PA, Stewart DE, Gnam WH, Goering PN (2001) Depressive symptoms as a determinant of breast and cervical cancer screening in women: a population-based study in Ontario, Canada. Arch Womens Ment Health, 14, 159-68.
  28. Walboomers JM, Jacobs MV, Manos MM, et al (1999) Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol, 189, 12-9. https://doi.org/10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F
  29. Wang SS, Schiffman M (2005) Medication use, medical conditions, and the risk of human papillomavirus infection and subsequent cervical intraepithelial neoplasia 3 among women with mild cytologic abnormalities. Cancer Epidemiol Biomarkers Prev, 14, 542-5. https://doi.org/10.1158/1055-9965.EPI-04-0642
  30. World Health Organization (WHO) (2013). GLOBOCAN 2012. Cervical cancer incidence and mortality worldwide in 2012 summary. Cancer fact sheet. (http://globocan.iarc.fr/Pages/fact_sheets_population.aspx)