Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
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Convergence study on the antioxidant effect of crude extracts of Nelumbo nucifera Gaertner

연밥 조추출물의 항산화 효능에 관한 융합 연구

  • Kim, Hyun-Jin (Department of Oral Anatomy, School of Dentistry, Wonkwang University, Institute of Biomaterial.Implant, Wonkwang University)
  • 김현진 (원광대학교 치과대학 구강해부학교실, 원광대학교 생체매식연구소)
  • Received : 2016.04.06
  • Accepted : 2016.05.20
  • Published : 2016.06.30
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Abstract

The present study was performed to evaluate the antioxidant effect of crude extracts of Nelumbo nucifera Gaertner. Antioxidant effect was analysed by DPPH-radical scavenging activity, lipid peroxidation and superoxide dismutase (SOD)-like activity. DPPH-radical scavenging activity and SOD-like activity of linoleic acid, glutamic acid, ethyl acetate crude extract and ethyl alcohol crude extract of Nelumbo nucifera Gaertner were dose-dependently increased. However, lipid peroxidation of glutamic acid, linoleic acid, ethyl acetate crude extract and ethyl alcohol crude extract of Nelumbo nucifera Gaertner were time-dependently decreased. The data suggests that crude extracts of Nelumbo nucifera Gaertner may be a putative antioxidant substance and apply the development of medicine through convergence study.

본 연구의 목적은 glutamic acid, linoleic acid, 연밥의 ethyl acetate 조추출물 및 ethyl alcohol 조추출물의 항산화효과를 알아보고자 하였다. 항산화능을 알아보고자 DPPH 라디칼 소거능, 지질과산화능 및 슈퍼옥사이드 디스뮤타제 유사활성을 측정하였다. Glutamic acid, linoleic acid, 연밥의 ethyl acetate 조추출물 및 ethyl alcohol 조추출물은 농도 의존적으로 DPPH 라디칼 소거능과 슈퍼옥사이드 디스뮤타제 유사활성을 증가시켰다. Glutamic acid, linoleic acid, 연밥의 ethyl acetate 조추출물 및 ethyl alcohol 조추출물은 대조군의 지질과산화의 증가에 비하여 시간 경과에 따른 반비례 양상으로 지질과산화가 감소하였다. 이상의 결과에서 연밥의 조추출물은 우수한 항산화능 물질이 존재 할 가능성을 제시하며 융합 연구를 통한 노화 방지 관련 의약품 개발 등에 응용되어질 수 있다.

Keywords

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